137393 20240321220236.0 10.1212/WNL.0000000000000271 doi pmid:24574548 pmid 0028-3878 ISSN 1526-632X ISSN altmetric:2230983 altmetric DZNE-2020-03715 English 610 Sajjadi, Seyed Ahmad P:(DE-HGF)0 0 Logopenic, mixed, or Alzheimer-related aphasia? [S.l.] 2014 Ovid online Crossref Ovid Technologies (Wolters Kluwer Health) 2014-02-26 print Crossref Ovid Technologies (Wolters Kluwer Health) 2014-04-01 article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1586863971_30144 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote This study tested the hypothesis that patients with primary progressive aphasia (PPA) who do not meet the proposed criteria for any of the recognized subtypes would have the atrophy pattern reported in the past for logopenic variant PPA (lvPPA), in turn suggesting that the PPA of likely Alzheimer disease origin is more variable than that captured in the current lvPPA diagnostic recommendations.MRI gray matter volumes from 14 patients with mixed PPA who failed to meet the diagnostic recommendations for any recognized variant were compared with those of 25 matched control participants via voxel-based morphometry.The mixed PPA group had left temporoparietal atrophy with a pattern identical to that in previously reported lvPPA cohorts.Patients with PPA who did not meet the criteria for any recognized PPA variant at their initial assessment had the group-level atrophy pattern previously reported as the hallmark of lvPPA. We suggest that the specific language features proposed for lvPPA are too narrow to characterize the language impairments arising from likely Alzheimer pathology. 344 - Clinical and Health Care Research (POF3-344) G:(DE-HGF)POF3-344 POF3-344 POF III 0 Dataset connected to CrossRef, PubMed, Aged MeSH Aged, 80 and over MeSH Alzheimer Disease: diagnosis MeSH Alzheimer Disease: psychology MeSH Aphasia, Primary Progressive: diagnosis MeSH Aphasia, Primary Progressive: psychology MeSH Female MeSH Humans MeSH Language Tests: standards MeSH Magnetic Resonance Imaging: standards MeSH Male MeSH Middle Aged MeSH Neuropsychological Tests: standards MeSH Patterson, Karalyn P:(DE-HGF)0 1 Nestor, Peter John P:(DE-2719)2810673 2 Last author 10.1212/wnl.0000000000000271 : Ovid Technologies (Wolters Kluwer Health), 2014-02-26 13 1127-1131 journal-article Crossref Neurology 82 2014 0028-3878 10.1212/WNL.0000000000000271 Vol. 82, no. 13, p. 1127 - 1131 PERI:(DE-600)1491874-2 13 82:13<1127 - 1131 1127-1131 Neurology 82 2014 0028-3878 VDB oai:pub.dzne.de:137393 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2810673 DE-HGF Forschungsbereich Gesundheit Erkrankungen des Nervensystems G:(DE-HGF)POF3-340 G:(DE-HGF)POF3-344 G:(DE-HGF)POF3-300 Clinical and Health Care Research 0 2014 Allianz-Lizenz StatID:(DE-HGF)0410 StatID JCR StatID:(DE-HGF)0100 StatID NEUROLOGY : 2017 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS DBCoverage StatID:(DE-HGF)0300 StatID Medline DBCoverage StatID:(DE-HGF)0310 StatID NCBI Molecular Biology Database DBCoverage StatID:(DE-HGF)0320 StatID PubMed Central DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List WoS StatID:(DE-HGF)0110 StatID Science Citation Index DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection WoS StatID:(DE-HGF)0111 StatID Science Citation Index Expanded DBCoverage StatID:(DE-HGF)1110 StatID Current Contents - Clinical Medicine DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - Life Sciences DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews IF >= 5 StatID:(DE-HGF)9905 StatID NEUROLOGY : 2017 I:(DE-2719)1310001 AG Nestor Cognitive Neurology and Neurodegeneration 0 journal VDB I:(DE-2719)1310001 UNRESTRICTED