% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Kabanova:137946,
      author       = {Kabanova, Anna and Pabst, Milan and Lorkowski, Markus and
                      Braganza, Oliver and Boehlen, Anne and Nikbakht, Negar and
                      Pothmann, Leonie and Vaswani, Ankita R and Musgrove, Ruth
                      and Di Monte, Donato A and Sauvage, Magdalena and Beck,
                      Heinz and Blaess, Sandra},
      title        = {{F}unction and developmental origin of a mesocortical
                      inhibitory circuit.},
      journal      = {Nature reviews / Neuroscience},
      volume       = {18},
      number       = {6},
      issn         = {1097-6256},
      address      = {London},
      publisher    = {Nature Publ. Group58142},
      reportid     = {DZNE-2020-04268},
      pages        = {872-882},
      year         = {2015},
      abstract     = {Midbrain ventral tegmental neurons project to the
                      prefrontal cortex and modulate cognitive functions. Using
                      viral tracing, optogenetics and electrophysiology, we found
                      that mesocortical neurons in the mouse ventrotegmental area
                      provide fast glutamatergic excitation of GABAergic
                      interneurons in the prefrontal cortex and inhibit prefrontal
                      cortical pyramidal neurons in a robust and reliable manner.
                      These mesocortical neurons were derived from a subset of
                      dopaminergic progenitors, which were dependent on prolonged
                      Sonic Hedgehog signaling for their induction. Loss of these
                      progenitors resulted in the loss of the mesocortical
                      inhibitory circuit and an increase in perseverative
                      behavior, whereas mesolimbic and mesostriatal dopaminergic
                      projections, as well as impulsivity and attentional
                      function, were largely spared. Thus, we identified a
                      previously uncharacterized mesocortical circuit contributing
                      to perseverative behaviors and found that the diversity of
                      dopaminergic neurons begins to be established during their
                      progenitor phase.},
      keywords     = {Animals / Attention: physiology / Behavior, Animal:
                      physiology / Cognition: physiology / Conditioning, Operant:
                      physiology / Dopaminergic Neurons: physiology / Glutamates:
                      physiology / Interneurons: physiology / Mice / Nerve Net:
                      growth $\&$ development / Nerve Net: physiology / Neurons:
                      physiology / Optogenetics / Prefrontal Cortex: cytology /
                      Prefrontal Cortex: growth $\&$ development / Prefrontal
                      Cortex: physiology / Pyramidal Cells: physiology / Reward /
                      Ventral Tegmental Area: cytology / Ventral Tegmental Area:
                      growth $\&$ development / Ventral Tegmental Area: physiology
                      / gamma-Aminobutyric Acid: physiology / Glutamates (NLM
                      Chemicals) / gamma-Aminobutyric Acid (NLM Chemicals)},
      cin          = {AG Di Monte / U Preclinical Researchers - Bonn},
      ddc          = {570},
      cid          = {I:(DE-2719)1013008 / I:(DE-2719)7000005},
      pnm          = {342 - Disease Mechanisms and Model Systems (POF3-342)},
      pid          = {G:(DE-HGF)POF3-342},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:25961790},
      doi          = {10.1038/nn.4020},
      url          = {https://pub.dzne.de/record/137946},
}