139122 20240722104745.0 0888-4897 ISSN 10.1177/1533317516678087 doi pmid:28100076 pmid 0895-5336 ISSN 1082-5207 ISSN 1533-3175 ISSN 1938-2731 ISSN DZNE-2020-05444 English 610 Haussmann, Robert P:(DE-HGF)0 0 Precuneus Structure Changes in Amnestic Mild Cognitive Impairment. Thousand Oaks, Calif. 2017 Sage online Crossref SAGE Publications 2016-11-15 print Crossref SAGE Publications 2017-02-01 article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1721638036_12030 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Patients with amnestic mild cognitive impairment (aMCI) are at risk for developing Alzheimer's disease. Due to their prominent memory impairment, structural magnetic resonance imaging (MRI) often focuses on the hippocampal region. However, recent positron-emission tomography data suggest that within a network of frontal and temporal changes, patients with aMCI show metabolic alterations in the precuneus, a key region for higher cognitive functions. Using high-resolution MRI and whole-brain cortical thickness analyses in 28 patients with aMCI and 25 healthy individuals, we wanted to investigate whether structural changes in the precuneus would be associated with cortical thickness reductions in frontal and temporal brain regions in patients with aMCI. In contrast to healthy people, patients with aMCI showed an association of cortical thinning in the precuneus with predominantly left-hemispheric thickness reductions in medial temporal and frontal cortices. Our data highlight structural neuronal network characteristics among patients with aMCI. 342 - Disease Mechanisms and Model Systems (POF3-342) G:(DE-HGF)POF3-342 POF3-342 POF III 0 344 - Clinical and Health Care Research (POF3-344) G:(DE-HGF)POF3-344 POF3-344 POF III 1 2016-11-15 Crossref http://journals.sagepub.com/page/policies/text-and-data-mining-license Dataset connected to CrossRef, PubMed, Aged MeSH Aged, 80 and over MeSH Amnesia: pathology MeSH Cerebral Cortex: pathology MeSH Cognitive Dysfunction: pathology MeSH Female MeSH Humans MeSH Magnetic Resonance Imaging: methods MeSH Male MeSH Middle Aged MeSH Parietal Lobe: pathology MeSH Werner, Annett P:(DE-HGF)0 1 Gruschwitz, Antonia 2 Osterrath, Antje P:(DE-2719)2810905 3 dzne Lange, Jan 4 Donix, Katharina L 5 Linn, Jennifer 6 Donix, Markus P:(DE-2719)2501739 7 Last author dzne 10.1177/1533317516678087 : SAGE Publications, 2016-11-15 1 22-26 journal-article Crossref American Journal of Alzheimer's Disease & Other Dementiasr 32 2016 1533-3175 10.1177/1533317516678087 Vol. 32, no. 1, p. 22 - 26 PERI:(DE-600)2235173-5 1 32:1<22 - 26 22-26 American journal of Alzheimer's disease and other dementias 32 2017 1533-3175 http://pub.dzne.de/record/139122/files/DZNE-2020-05444_Restricted.pdf http://pub.dzne.de/record/139122/files/DZNE-2020-05444_Restricted.pdf?subformat=pdfa pdfa VDB oai:pub.dzne.de:139122 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 3 P:(DE-2719)2810905 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 7 P:(DE-2719)2501739 DE-HGF Gesundheit Erkrankungen des Nervensystems G:(DE-HGF)POF3-340 G:(DE-HGF)POF3-342 G:(DE-HGF)POF3 G:(DE-HGF)POF3-300 G:(DE-HGF)POF Disease Mechanisms and Model Systems 0 DE-HGF Gesundheit Erkrankungen des Nervensystems G:(DE-HGF)POF3-340 G:(DE-HGF)POF3-344 G:(DE-HGF)POF3 G:(DE-HGF)POF3-300 G:(DE-HGF)POF Clinical and Health Care Research 1 2017 National-Konsortium StatID:(DE-HGF)0430 StatID 2022-11-19 ger DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-19 DBCoverage StatID:(DE-HGF)0501 StatID DOAJ Seal 2022-09-27T09:56:46Z DBCoverage StatID:(DE-HGF)0500 StatID DOAJ 2022-09-27T09:56:46Z Peer Review StatID:(DE-HGF)0030 StatID DOAJ : Blind peer review 2022-09-27T09:56:46Z DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-19 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-19 DBCoverage StatID:(DE-HGF)1110 StatID Current Contents - Clinical Medicine 2022-11-19 JCR StatID:(DE-HGF)0100 StatID AM J ALZHEIMERS DIS : 2021 2022-11-19 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-19 IF < 5 StatID:(DE-HGF)9900 StatID 2022-11-19 I:(DE-2719)999999 Pre 2020 DZNE before 2020 0 I:(DE-2719)1740001 AG Garthe Technology Platform Neurobiology of Behaviour 1 I:(DE-2719)1710012 AG Falkenburger Translational Parkinson Research 2 journal VDB I:(DE-2719)999999 I:(DE-2719)1740001 I:(DE-2719)1710012 UNRESTRICTED -- missing cx lookup -- 10.1111/j.1365-2796.2004.01388.x Crossref 10.1111/j.1365-2796.2004.01388.x -- missing cx lookup -- 10.1001/archneur.56.3.303 Crossref 10.1001/archneur.56.3.303 -- missing cx lookup -- 10.1001/archneurol.2009.266 Crossref 10.1001/archneurol.2009.266 -- missing cx lookup -- 10.1159/000115751 Crossref 10.1159/000115751 -- missing cx lookup -- 10.1212/WNL.59.2.198 Crossref 10.1212/WNL.59.2.198 -- missing cx lookup -- 10.3233/JAD-150625 Crossref 10.3233/JAD-150625 -- missing cx lookup -- 10.3233/JAD-122002 Crossref 10.3233/JAD-122002 -- missing cx lookup -- 10.1212/WNL.0b013e31826e26b7 Crossref 10.1212/WNL.0b013e31826e26b7 -- missing cx lookup -- 10.1016/j.archger.2007.01.032 Crossref 10.1016/j.archger.2007.01.032 -- missing cx lookup -- 10.2174/156720509788929273 Crossref 10.2174/156720509788929273 2011 Crossref Burggren AC 2011 -- missing cx lookup -- 10.1159/000148190 Crossref 10.1159/000148190 -- missing cx lookup -- 10.1016/j.neuroimage.2010.03.040 Crossref 10.1016/j.neuroimage.2010.03.040 -- missing cx lookup -- 10.1155/2015/583931 Crossref 10.1155/2015/583931 -- missing cx lookup -- 10.1097/RLU.0000000000000666 Crossref 10.1097/RLU.0000000000000666 -- missing cx lookup -- 10.1186/s13195-015-0143-0 Crossref 10.1186/s13195-015-0143-0 -- missing cx lookup -- 10.1093/brain/awl004 Crossref 10.1093/brain/awl004 -- missing cx lookup -- 10.3389/fnagi.2016.00052 Crossref 10.3389/fnagi.2016.00052 -- missing cx lookup -- 10.1006/nimg.1998.0395 Crossref 10.1006/nimg.1998.0395 -- missing cx lookup -- 10.1073/pnas.200033797 Crossref 10.1073/pnas.200033797 -- missing cx lookup -- 10.1006/nimg.1998.0396 Crossref 10.1006/nimg.1998.0396 -- missing cx lookup -- 10.1093/cercor/bhg087 Crossref 10.1093/cercor/bhg087 -- missing cx lookup -- 10.1016/j.neuroimage.2010.06.010 Crossref 10.1016/j.neuroimage.2010.06.010 -- missing cx lookup -- 10.1212/WNL.58.5.695 Crossref 10.1212/WNL.58.5.695 -- missing cx lookup -- 10.1016/j.neuroimage.2006.02.051 Crossref 10.1016/j.neuroimage.2006.02.051 -- missing cx lookup -- 10.1006/nimg.2001.1037 Crossref 10.1006/nimg.2001.1037 -- missing cx lookup -- 10.1007/BF00308809 Crossref 10.1007/BF00308809 -- missing cx lookup -- 10.3346/jkms.2015.30.6.779 Crossref 10.3346/jkms.2015.30.6.779 -- missing cx lookup -- 10.2174/1567205013666151218150534 Crossref 10.2174/1567205013666151218150534