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@ARTICLE{Lessard:140184,
author = {Lessard, Isabelle and Brais, Bernard and Côté, Isabelle
and Lavoie, Caroline and Synofzik, Matthis and Mathieu, Jean
and Gagnon, Cynthia},
title = {{A}ssessing mobility and balance in {A}utosomal {R}ecessive
{S}pastic {A}taxia of {C}harlevoix-{S}aguenay population:
{V}alidity and reliability of four outcome measures.},
journal = {Journal of the neurological sciences},
volume = {390},
issn = {0022-510X},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {DZNE-2020-06506},
pages = {4-9},
year = {2018},
abstract = {To assess the construct validity of the 10-Meter Walk Test
(10mWT), Six-Minute Walk Test (6MWT), Berg Balance Scale
(BERG), and Timed Up and Go (TUG) in adults with Autosomal
Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS), in
addition to the interrater reliability of the 10mWT and
6MWT.Reliability was determined using the intraclass
correlation coefficient (ICC). Validity was determined first
by correlating the 10mWT, 6MWT, BERG, and TUG with
participant's age, lower limb coordination, and disease
severity, and then by assessing their capacity to
distinguish between participants based on sex and disease
stages.Interrater reliability of the 10mWT at both
comfortable and maximum speed as well as the 6MWT is
excellent (ICC = 0.97-0.99). Construct validity of the
four tests was confirmed, as showed by the high correlations
with age, lower limb coordination, and overall disease
severity (ρ = 0.64-0.97).The four tests assessed for
their metrological properties in this study showed to be
valid instruments to use in the ARSACS population. The 10mWT
and 6MWT are also highly reliable. BERG and TUG reliability
will need to be assess in a future study.},
keywords = {Adolescent / Adult / Biomechanical Phenomena / Disease
Progression / Female / Humans / Male / Middle Aged /
Movement / Muscle Spasticity: diagnosis / Muscle Spasticity:
physiopathology / Muscle Spasticity: rehabilitation /
Postural Balance / Reproducibility of Results / Severity of
Illness Index / Sex Characteristics / Spinocerebellar
Ataxias: congenital / Spinocerebellar Ataxias: diagnosis /
Spinocerebellar Ataxias: physiopathology / Spinocerebellar
Ataxias: rehabilitation / Walk Test: methods / Wheelchairs /
Young Adult},
cin = {AG Gasser},
ddc = {610},
cid = {I:(DE-2719)1210000},
pnm = {345 - Population Studies and Genetics (POF3-345)},
pid = {G:(DE-HGF)POF3-345},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29801904},
doi = {10.1016/j.jns.2018.03.033},
url = {https://pub.dzne.de/record/140184},
}