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024 7 _ |a 10.1016/j.jns.2018.03.033
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024 7 _ |a pmid:29801904
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024 7 _ |a 0022-510X
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024 7 _ |a 1878-5883
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037 _ _ |a DZNE-2020-06506
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Lessard, Isabelle
|0 P:(DE-HGF)0
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245 _ _ |a Assessing mobility and balance in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay population: Validity and reliability of four outcome measures.
260 _ _ |a Amsterdam [u.a.]
|c 2018
|b Elsevier Science
264 _ 1 |3 print
|2 Crossref
|b Elsevier BV
|c 2018-07-01
336 7 _ |a article
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a To assess the construct validity of the 10-Meter Walk Test (10mWT), Six-Minute Walk Test (6MWT), Berg Balance Scale (BERG), and Timed Up and Go (TUG) in adults with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS), in addition to the interrater reliability of the 10mWT and 6MWT.Reliability was determined using the intraclass correlation coefficient (ICC). Validity was determined first by correlating the 10mWT, 6MWT, BERG, and TUG with participant's age, lower limb coordination, and disease severity, and then by assessing their capacity to distinguish between participants based on sex and disease stages.Interrater reliability of the 10mWT at both comfortable and maximum speed as well as the 6MWT is excellent (ICC = 0.97-0.99). Construct validity of the four tests was confirmed, as showed by the high correlations with age, lower limb coordination, and overall disease severity (ρ = 0.64-0.97).The four tests assessed for their metrological properties in this study showed to be valid instruments to use in the ARSACS population. The 10mWT and 6MWT are also highly reliable. BERG and TUG reliability will need to be assess in a future study.
536 _ _ |a 345 - Population Studies and Genetics (POF3-345)
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542 _ _ |i 2018-07-01
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588 _ _ |a Dataset connected to CrossRef, PubMed,
650 _ 2 |a Adolescent
|2 MeSH
650 _ 2 |a Adult
|2 MeSH
650 _ 2 |a Biomechanical Phenomena
|2 MeSH
650 _ 2 |a Disease Progression
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Movement
|2 MeSH
650 _ 2 |a Muscle Spasticity: diagnosis
|2 MeSH
650 _ 2 |a Muscle Spasticity: physiopathology
|2 MeSH
650 _ 2 |a Muscle Spasticity: rehabilitation
|2 MeSH
650 _ 2 |a Postural Balance
|2 MeSH
650 _ 2 |a Reproducibility of Results
|2 MeSH
650 _ 2 |a Severity of Illness Index
|2 MeSH
650 _ 2 |a Sex Characteristics
|2 MeSH
650 _ 2 |a Spinocerebellar Ataxias: congenital
|2 MeSH
650 _ 2 |a Spinocerebellar Ataxias: diagnosis
|2 MeSH
650 _ 2 |a Spinocerebellar Ataxias: physiopathology
|2 MeSH
650 _ 2 |a Spinocerebellar Ataxias: rehabilitation
|2 MeSH
650 _ 2 |a Walk Test: methods
|2 MeSH
650 _ 2 |a Wheelchairs
|2 MeSH
650 _ 2 |a Young Adult
|2 MeSH
700 1 _ |a Brais, Bernard
|0 P:(DE-HGF)0
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700 1 _ |a Côté, Isabelle
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700 1 _ |a Lavoie, Caroline
|0 P:(DE-HGF)0
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700 1 _ |a Synofzik, Matthis
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700 1 _ |a Mathieu, Jean
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700 1 _ |a Gagnon, Cynthia
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773 1 8 |a 10.1016/j.jns.2018.03.033
|b : Elsevier BV, 2018-07-01
|p 4-9
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|t Journal of the Neurological Sciences
|v 390
|y 2018
|x 0022-510X
773 _ _ |a 10.1016/j.jns.2018.03.033
|g Vol. 390, p. 4 - 9
|0 PERI:(DE-600)1500645-1
|q 390<4 - 9
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|t Journal of the neurological sciences
|v 390
|y 2018
|x 0022-510X
856 4 _ |u https://pub.dzne.de/record/140184/files/DZNE-2020-06506_Restricted.pdf
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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