151522 20230915101357.0 10.1093/geronb/gby083 doi 1079-5014 ISSN 1758-5368 ISSN altmetric:77287070 altmetric pmid:29986090 pmid DZNE-2020-01106 English 570 Heser, Kathrin P:(DE-HGF)0 0 Corresponding author Late-Life Depressive Symptoms Are Associated With Functional Impairment Cross-sectionally and Over Time: Results of the AgeMooDe Study Oxford [u.a.] 2018 Oxford Univ. Press online Crossref Oxford University Press (OUP) 2018-07-06 article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1600952360_14346 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote ObjectivesThis study examines the relationship between late-life depressive symptoms, cognitive and functional impairment in a cohort of very old community-based participants.MethodsA sample of 1,226 primary care patients was assessed at baseline (Mage = 80.6 years). Statistical analyses were conducted using baseline and 12-month follow-up data.ResultsAt baseline, depressed participants showed minor cognitive deficits compared with nondepressed participants, whereas functional deficits were pronounced. Depressive symptoms and global cognition were not associated longitudinally. In contrast, follow-up functional impairment was predicted by baseline level and increase of depressive symptoms between baseline and follow-up. Reversely, follow-up depressive symptoms were predicted by functional decline between baseline and follow-up, whereas baseline functional status was not predictive.DiscussionDepressive symptoms and global cognitive function were not associated longitudinally, but level and increase of depressive symptoms over time predicted functional impairment after 1 year. Interventions to reduce depressive symptoms, or to encourage coping strategies might be promising to reduce functional impairment. Elevated follow-up depressive symptoms were only predicted by functional decline, supposedly emphasizing that incident functional impairment might be associated with an acute increase of depressive symptoms. Psychological adjustment processes were not examined, but might be targeted in future. 899H - Addenda (POF3-899H) G:(DE-HGF)POF3-899H POF3-899H POF III 0 2018-07-06 Crossref https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model Dataset connected to CrossRef Activities of Daily Living: psychology MeSH Age Factors MeSH Aged MeSH Aged, 80 and over MeSH Aging: psychology MeSH Cognitive Dysfunction: complications MeSH Cognitive Dysfunction: psychology MeSH Cohort Studies MeSH Depression: complications MeSH Depression: psychology MeSH Female MeSH Follow-Up Studies MeSH Geriatric Assessment MeSH Humans MeSH Longitudinal Studies MeSH Male MeSH Risk Factors MeSH Stein, Janine 1 Luppa, Melanie 2 Wiese, Birgitt 3 Mamone, Silke 4 Weyerer, Siegfried 5 Werle, Jochen 6 König, Hans-Helmut 7 Hajek, André 8 Scherer, Martin 9 Stark, Anne 10 Kaduszkiewicz, Hanna 11 Maier, Wolfgang P:(DE-HGF)0 12 Riedel-Heller, Steffi G 13 Wagner, Michael P:(DE-2719)2000057 14 Last author 10.1093/geronb/gby083 : Oxford University Press (OUP), 2018-07-06 journal-article Crossref The Journals of Gerontology: Series B 2018 1079-5014 10.1093/geronb/gby083 PERI:(DE-600)2043945-3 4 811 - 820 The journals of gerontology / B 75 2018 1079-5014 https://academic.oup.com/psychsocgerontology/article/75/4/811/5050184 oai:pub.dzne.de:151522 VDB Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 14 P:(DE-2719)2000057 DE-HGF Programmungebundene Forschung ohne Programm G:(DE-HGF)POF3-890 G:(DE-HGF)POF3-899H G:(DE-HGF)POF3-800 Addenda 0 2018 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2020-02-27 Nationallizenz StatID:(DE-HGF)0420 StatID 2022-11-22 ger JCR StatID:(DE-HGF)0100 StatID J GERONTOL B-PSYCHOL : 2021 2022-11-22 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-22 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-22 DBCoverage StatID:(DE-HGF)0600 StatID Ebsco Academic Search 2022-11-22 Peer Review StatID:(DE-HGF)0030 StatID ASC 2022-11-22 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-22 DBCoverage StatID:(DE-HGF)1180 StatID Current Contents - Social and Behavioral Sciences 2022-11-22 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-22 DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - 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