153265 20230915094009.0 pmid:32581724 pmid 10.3389/fncir.2020.00020 doi altmetric:83975966 altmetric pmc:PMC7291770 pmc DZNE-2020-01262 English 610 Stahn, Alexander Christoph P:(DE-HGF)0 0 Corresponding author Spatial Updating Depends on Gravity Lausanne 2020 Frontiers Research Foundation article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1605877865_21602 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote As we move through an environment the positions of surrounding objects relative to our body constantly change. Maintaining orientation requires spatial updating, the continuous monitoring of self-motion cues to update external locations. This ability critically depends on the integration of visual, proprioceptive, kinesthetic, and vestibular information. During weightlessness gravity no longer acts as an essential reference, creating a discrepancy between vestibular, visual and sensorimotor signals. Here, we explore the effects of repeated bouts of microgravity and hypergravity on spatial updating performance during parabolic flight. Ten healthy participants (four women, six men) took part in a parabolic flight campaign that comprised a total of 31 parabolas. Each parabola created about 20–25 s of 0 g, preceded and followed by about 20 s of hypergravity (1.8 g). Participants performed a visual-spatial updating task in seated position during 15 parabolas. The task included two updating conditions simulating virtual forward movements of different lengths (short and long), and a static condition with no movement that served as a control condition. Two trials were performed during each phase of the parabola, i.e., at 1 g before the start of the parabola, at 1.8 g during the acceleration phase of the parabola, and during 0 g. Our data demonstrate that 0 g and 1.8 g impaired pointing performance for long updating trials as indicated by increased variability of pointing errors compared to 1 g. In contrast, we found no support for any changes for short updating and static conditions, suggesting that a certain degree of task complexity is required to affect pointing errors. These findings are important for operational requirements during spaceflight because spatial updating is pivotal for navigation when vision is poor or unreliable and objects go out of sight, for example during extravehicular activities in space or the exploration of unfamiliar environments. Future studies should compare the effects on spatial updating during seated and free-floating conditions, and determine at which g-threshold decrements in spatial updating performance emerge. 344 - Clinical and Health Care Research (POF3-344) G:(DE-HGF)POF3-344 POF3-344 POF III 0 Dataset connected to CrossRef Adult MeSH Female MeSH Gravitation MeSH Gravity Sensing: physiology MeSH Humans MeSH Hypergravity MeSH Male MeSH Middle Aged MeSH Orientation, Spatial: physiology MeSH Space Flight: methods MeSH Space Flight: psychology MeSH Spatial Navigation: physiology MeSH Weightlessness MeSH Riemer, Martin P:(DE-2719)2813753 1 dzne Wolbers, Thomas P:(DE-2719)2810583 2 dzne Werner, Anika 3 Brauns, Katharina 4 Besnard, Stephane 5 Denise, Pierre 6 Kühn, Simone 7 Gunga, Hanns-Christian 8 10.3389/fncir.2020.00020 Vol. 14, p. 20 PERI:(DE-600)2452968-0 20 Frontiers in neural circuits 14 2020 1662-5110 https://www.frontiersin.org/articles/10.3389/fncir.2020.00020/full http://pub.dzne.de/record/153265/files/7023.pdf OpenAccess http://pub.dzne.de/record/153265/files/7023.gif?subformat=icon icon OpenAccess http://pub.dzne.de/record/153265/files/7023.jpg?subformat=icon-1440 icon-1440 OpenAccess http://pub.dzne.de/record/153265/files/7023.jpg?subformat=icon-180 icon-180 OpenAccess http://pub.dzne.de/record/153265/files/7023.jpg?subformat=icon-640 icon-640 OpenAccess http://pub.dzne.de/record/153265/files/7023.pdf?subformat=pdfa pdfa OpenAccess oai:pub.dzne.de:153265 openaire open_access VDB driver dnbdelivery Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 1 P:(DE-2719)2813753 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2810583 DE-HGF Forschungsbereich Gesundheit Erkrankungen des Nervensystems G:(DE-HGF)POF3-340 G:(DE-HGF)POF3-344 G:(DE-HGF)POF3-300 Clinical and Health Care Research 0 2020 Creative Commons Attribution CC BY (No Version) LIC:(DE-HGF)CCBYNV V:(DE-HGF) DOAJ 2020-09-09 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2020-09-09 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2020-09-09 Fees StatID:(DE-HGF)0700 StatID 2020-09-09 OpenAccess StatID:(DE-HGF)0510 StatID Article Processing Charges StatID:(DE-HGF)0561 StatID 2020-09-09 JCR StatID:(DE-HGF)0100 StatID FRONT NEURAL CIRCUIT : 2021 2022-11-19 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-19 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-19 DBCoverage StatID:(DE-HGF)0501 StatID DOAJ Seal 2021-05-11T13:05:11Z DBCoverage StatID:(DE-HGF)0500 StatID DOAJ 2021-05-11T13:05:11Z Peer Review StatID:(DE-HGF)0030 StatID DOAJ : Blind peer review 2021-05-11T13:05:11Z DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-19 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-19 IF < 5 StatID:(DE-HGF)9900 StatID 2022-11-19 I:(DE-2719)1710012 AG Falkenburger Clinical Study Team Dresden 0 I:(DE-2719)1310002 AG Wolbers Aging & Cognition 1 journal VDB UNRESTRICTED I:(DE-2719)1710012 I:(DE-2719)1310002 FullTexts