155570 20250414153737.0 pmc:PMC8803276 pmc 10.1111/jsr.13347 doi pmid:33913199 pmid 0962-1105 ISSN 1365-2869 ISSN altmetric:104926420 altmetric DZNE-2021-00748 English 610 Tahmasian, Masoud 0000-0003-3999-3807 0 Corresponding author ENIGMA-Sleep: Challenges, opportunities, and the road map. Oxford [u.a.] 2021 Wiley-Blackwell article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1744637812_21649 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine. 353 - Clinical and Health Care Research (POF4-353) G:(DE-HGF)POF4-353 POF4-353 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de ENIGMA consortium Other large-scale collaboration Other neurogenetics Other neuroimaging Other sleep Other Brain: diagnostic imaging MeSH Humans MeSH Neuroimaging MeSH Sample Size MeSH Sleep Deprivation MeSH Aleman, André 1 Andreassen, Ole A P:(DE-2719)9001146 2 dzne Arab, Zahra 0000-0001-6210-4532 3 Baillet, Marion 4 Benedetti, Francesco 5 Bresser, Tom 6 Bright, Joanna 0000-0002-0695-0491 7 Chee, Michael W L 8 Chylinski, Daphne 9 Cheng, Wei 10 Deantoni, Michele 11 Dresler, Martin 12 Eickhoff, Simon B 13 Eickhoff, Claudia R 14 Elvsåshagen, Torbjørn 15 Feng, Jianfeng 16 Foster-Dingley, Jessica C 17 Ganjgahi, Habib 18 Grabe, Hans J P:(DE-2719)2811781 19 dzne Groenewold, Nynke A 20 Ho, Tiffany C 21 Bong Hong, Seung 22 Houenou, Josselin 0000-0003-3166-5606 23 Irungu, Benson 24 Jahanshad, Neda 25 Khazaie, Habibolah 26 Kim, Hosung 27 Koshmanova, Ekaterina 28 Kocevska, Desi 29 Kochunov, Peter 30 Lakbila-Kamal, Oti 31 Leerssen, Jeanne 32 Li, Meng 33 Luik, Annemarie I 0000-0001-7517-197X 34 Muto, Vincenzo 0000-0001-5100-9927 35 Narbutas, Justinas 36 Nilsonne, Gustav 0000-0001-5273-0150 37 O'Callaghan, Victoria S 0000-0002-0818-1323 38 Olsen, Alexander 0000-0001-8691-3860 39 Osorio, Ricardo S 0000-0002-2735-9609 40 Poletti, Sara 41 Poudel, Govinda 42 Reesen, Joyce E 43 Reneman, Liesbeth 44 Reyt, Mathilde 45 Riemann, Dieter 0000-0002-1968-6220 46 Rosenzweig, Ivana 0000-0003-2152-9694 47 Rostampour, Masoumeh 48 Saberi, Amin 0000-0002-7043-0722 49 Schiel, Julian 50 Schmidt, Christina 51 Schrantee, Anouk 52 Sciberras, Emma 53 Silk, Tim J 54 Sim, Kang 55 Smevik, Hanne 0000-0002-7361-9387 56 Soares, Jair C 57 Spiegelhalder, Kai 58 Stein, Dan J 59 Talwar, Puneet 60 Tamm, Sandra 61 Teresi, Giana L 62 Valk, Sofie L 0000-0003-2998-6849 63 Van Someren, Eus 0000-0002-9970-8791 64 Vandewalle, Gilles 0000-0003-2483-2752 65 Van Egroo, Maxime 66 Völzke, Henry 67 Walter, Martin 68 Wassing, Rick 0000-0003-2346-9891 69 Weber, Frederik D 70 Weihs, Antoine 0000-0002-7113-0027 71 Westlye, Lars Tjelta 72 Wright, Margaret J 0000-0001-7133-4970 73 Wu, Mon-Ju 74 Zak, Nathalia 75 Zarei, Mojtaba 76 10.1111/jsr.13347 PERI:(DE-600)2007459-1 6 e13347 Journal of sleep research 30 2021 1365-2869 https://onlinelibrary.wiley.com/doi/10.1111/jsr.13347 http://pub.dzne.de/record/155570/files/DZNE-2021-00748_Restricted.pdf http://pub.dzne.de/record/155570/files/DZNE-2021-00748_Restricted.pdf?subformat=pdfa pdfa VDB oai:pub.dzne.de:155570 External Institute I:(DE-HGF)0 Extern 2 P:(DE-2719)9001146 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 19 P:(DE-2719)2811781 DE-HGF Gesundheit Neurodegenerative Diseases G:(DE-HGF)POF4-350 G:(DE-HGF)POF4-353 G:(DE-HGF)POF4 G:(DE-HGF)POF4-300 G:(DE-HGF)POF Clinical and Health Care Research 0 DE-HGF Gesundheit Erkrankungen des Nervensystems G:(DE-HGF)POF3-340 G:(DE-HGF)POF3-344 G:(DE-HGF)POF3 G:(DE-HGF)POF3-300 G:(DE-HGF)POF Clinical and Health Care Research 0 2021 DEAL Wiley StatID:(DE-HGF)3001 StatID 2021-01-29 ger DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2021-01-29 DBCoverage StatID:(DE-HGF)1190 StatID Biological Abstracts 2021-01-29 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2021-01-29 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-12 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-12 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-12 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-12 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2022-11-12 DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - Life Sciences 2022-11-12 JCR StatID:(DE-HGF)0100 StatID J SLEEP RES : 2021 2022-11-12 DBCoverage StatID:(DE-HGF)0600 StatID Ebsco Academic Search 2022-11-12 Peer Review StatID:(DE-HGF)0030 StatID ASC 2022-11-12 IF >= 5 StatID:(DE-HGF)9905 StatID J SLEEP RES : 2021 2022-11-12 I:(DE-2719)5000001 AG Grabe Biomarkers of Dementia in the General Population 0 journal VDB I:(DE-2719)5000001 UNRESTRICTED