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@ARTICLE{Hansen:155986,
      author       = {Hansen, Niels and Luedecke, Daniel and Malchow, Berend and
                      Lipp, Michael and Vogelgsang, Jonathan and Timäus, Charles
                      and Zindler, Tristan and Gingele, Stefan and Kühn, Simone
                      and Gallinat, Jürgen and Wiedemann, Klaus and Denk,
                      Johannes and Moschny, Nicole and Fiehler, Jens and
                      Skripuletz, Thomas and Riedel, Christian and Wattjes, Mike P
                      and Zerr, Inga and Esselmann, Hermann and Poustka, Luise and
                      Karow, Anne and Hartmann, Hans and Frieling, Helge and
                      Bleich, Stefan and Wiltfang, Jens and Neyazi, Alexandra},
      collaboration = {CAP, +},
      title        = {{A}utoantibody-associated psychiatric syndromes in
                      children: link to adult psychiatry.},
      journal      = {Journal of neural transmission},
      volume       = {128},
      number       = {6},
      issn         = {1435-1463},
      address      = {Wien [u.a.]},
      publisher    = {Springer},
      reportid     = {DZNE-2021-01118},
      pages        = {735 - 747},
      year         = {2021},
      abstract     = {Studies show that psychiatric symptoms in adults and
                      children are sometimes associated with serum neural
                      autoantibodies. The significance of serum neural
                      autoantibodies associated with psychiatric symptoms in
                      children remains often unclear, but might be relevant for
                      the extent and occurrence of psychiatric disease
                      manifestation in later life, as well as therapy and outcome.
                      For this narrative review, we sought articles listed in
                      PubMed and published between 1988 and 2020 addressing the
                      maternal-fetal transfer of neural autoantibodies and
                      psychiatric disorders associated with serum neural
                      autoantibodies. We identified six major subgroups of
                      psychiatric disorders in children that are associated with
                      serum neural autoantibodies: patients with attentional
                      deficit hyperactivity disorder, autism spectrum disorder,
                      obsessive compulsive disorder, Gilles de la Tourette
                      syndrome, psychosis and catatonia. Furthermore, we
                      summarized study findings from maternal-fetal transfer of
                      Contactin-associated protein-like 2, N-methyl-D-aspartate
                      receptor and fetal brain autoantibodies associated with
                      behavioral effects in animals and humans. We hypothesize
                      that the maternal transfer of serum neuronal autoantibodies
                      during or after birth could result (1) in the ignition of an
                      autoimmune-mediated inflammation having neurodevelopmental
                      consequences for their children (autoimmune-priming-attack
                      hypothesis) and (2) has a potential impact on the later
                      manifestation of psychiatric disorders. Through this
                      narrative review, we propose a diagnostic pathway for the
                      clinical diagnosis of a potentially autoimmune origin of
                      psychiatric symptoms in children while considering recent
                      guidelines.},
      subtyp        = {Review Article},
      keywords     = {Adult / Animals / Autism Spectrum Disorder / Autoantibodies
                      / Child / Humans / Obsessive-Compulsive Disorder /
                      Psychiatry / Psychotic Disorders},
      cin          = {AG Wiltfang},
      ddc          = {610},
      cid          = {I:(DE-2719)1410006},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34057596},
      pmc          = {pmc:PMC8205901},
      doi          = {10.1007/s00702-021-02354-8},
      url          = {https://pub.dzne.de/record/155986},
}