163304 20240322115504.0 1868-8497 ISSN 10.1007/s12672-021-00422-9 doi pmid:35201440 pmid pmc:PMC8777500 pmc altmetric:112724111 altmetric 1868-8500 ISSN 2730-6011 ISSN DZNE-2022-00084 English 610 Sun, Qiang 0000-0001-8094-2214 0 Recent advances in cancer immunotherapy. [New York] 2021 Springer article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1711022460_32502 PUB:(DE-HGF) Review Article ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Journal: Discover Oncology, ISSN: 2730-6011 Cancer immunotherapy represents a major advance in the cure of cancer following the dramatic advancements in the development and refinement of chemotherapies and radiotherapies. In the recent decades, together with the development of early diagnostic techniques, immunotherapy has significantly contributed to improving the survival of cancer patients. The immune-checkpoint blockade agents have been proven effective in a significant fraction of standard therapy refractory patients. Importantly, recent advances are providing alternative immunotherapeutic tools that could help overcome their limitations. In this mini review, we provide an overview on the main steps of the discovery of classic immune-checkpoint blockade agents and summarise the most recent development of novel immunotherapeutic strategies, such as tumour antigens, bispecific antibodies and TCR-engineered T cells. 351 - Brain Function (POF4-351) G:(DE-HGF)POF4-351 POF4-351 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de Cancer immunotherapy Other Cancer survival Other Immune check point blockade Other KRas Other T cell receptor Other p53 Other Melino, Gerry P:(DE-2719)9001390 1 dzne Amelio, Ivano 0000-0003-0739-325X 2 Jiang, Jingting 0000-0002-3128-9762 3 Wang, Ying 0000-0002-2571-9367 4 Shi, Yufang 0000-0001-8964-319X 5 10.1007/s12672-021-00422-9 Vol. 12, no. 1, p. 27 PERI:(DE-600)3059869-2 1 27 Discover oncology 12 2021 1868-8497 OpenAccess http://pub.dzne.de/record/163304/files/DZNE-2022-00084.pdf OpenAccess pdfa http://pub.dzne.de/record/163304/files/DZNE-2022-00084.pdf?subformat=pdfa oai:pub.dzne.de:163304 openaire open_access VDB driver dnbdelivery Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 1 P:(DE-2719)9001390 DE-HGF Gesundheit Neurodegenerative Diseases G:(DE-HGF)POF4-350 G:(DE-HGF)POF4-351 G:(DE-HGF)POF4 G:(DE-HGF)POF4-300 G:(DE-HGF)POF Brain Function 0 2021 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-29 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2022-11-29 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2022-11-29 DBCoverage StatID:(DE-HGF)1190 StatID Biological Abstracts 2022-11-29 Creative Commons Attribution CC BY 4.0 LIC:(DE-HGF)CCBY4 HGFVOC Peer Review StatID:(DE-HGF)0030 StatID DOAJ : Blind peer review 2021-07-21T15:23:25Z DBCoverage StatID:(DE-HGF)0501 StatID DOAJ Seal 2021-07-21T15:23:25Z DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-29 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2022-11-29 Fees StatID:(DE-HGF)0700 StatID 2022-11-29 OpenAccess StatID:(DE-HGF)0510 StatID DBCoverage StatID:(DE-HGF)0500 StatID DOAJ 2021-07-21T15:23:25Z Article Processing Charges StatID:(DE-HGF)0561 StatID 2022-11-29 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-29 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-29 I:(DE-2719)5000018 AG Nicotera Synaptic Connectivity and Neurodegeneration 0 journal VDB UNRESTRICTED I:(DE-2719)5000018 FullTexts