163951 20230915090539.0 10.1055/a-1743-2915 doi pmid:35405744 pmid 0015-8194 ISSN 0720-4299 ISSN 1439-3522 ISSN DZNE-2022-00625 German 150 Wagemann, Olivia P:(DE-2719)9001249 0 First author dzne Regression bei jungen Erwachsenen mit einem Down-Syndrom: Eine Fallserie. Stuttgart [u.a.] 2022 Thieme article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1667897665_7091 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Regression in young adults with Down syndrome can present itself with an acute loss of acquired skills and change in behavior. The aim of our case series was to describe the heterogeneous clinical presentation of this syndrome as well as accompanying diagnostic and therapeutic challenges and consequences.All three patients were assessed with the CAMDEX-DS (Cambridge Examination for Mental Disorders of Older People with Down Syndrome and Others with Intellectual Disabilities) and the criteria published by the DSMIG-USA (Down-Syndrome Medical Interest Group USA).After ruling out somatic or other psychiatric causes, the application of the DSMIG-USA criteria resulted in diagnosing at least a probable unexplained regression in all three patients.The thorough diagnostic investigation of unexplained acute regression in young adults with Down syndrome allows for quick initiation of therapeutic and supportive measures. Using the DMSIG-USA criteria facilitates the assessment of the underlying diffuse and heterogenous pathology. 353 - Clinical and Health Care Research (POF4-353) G:(DE-HGF)POF4-353 POF4-353 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de Aged MeSH Cognition MeSH Down Syndrome: complications MeSH Humans MeSH Intellectual Disability: complications MeSH Young Adult MeSH Loosli, Sandra V 1 Vöglein, Jonathan P:(DE-2719)2811820 2 dzne Prix, Catharina P:(DE-2719)9001508 3 dzne Wlasich, Elisabeth 4 Nuebling, Georg Sebastian Otto P:(DE-2719)9001761 5 dzne Danek, Adrian P:(DE-2719)2810712 6 dzne Levin, Johannes P:(DE-2719)2811659 7 Last author dzne 10.1055/a-1743-2915 p. a-1743-2915 PERI:(DE-600)2037701-0 10 465-470 Fortschritte der Neurologie, Psychiatrie 90 2022 0015-8194 VDB oai:pub.dzne.de:163951 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 0 P:(DE-2719)9001249 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2811820 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 3 P:(DE-2719)9001508 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 5 P:(DE-2719)9001761 External Institute I:(DE-HGF)0 Extern 6 P:(DE-2719)2810712 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 7 P:(DE-2719)2811659 DE-HGF Gesundheit Neurodegenerative Diseases G:(DE-HGF)POF4-350 G:(DE-HGF)POF4-353 G:(DE-HGF)POF4 G:(DE-HGF)POF4-300 G:(DE-HGF)POF Clinical and Health Care Research 0 2022 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2021-02-03 DBCoverage StatID:(DE-HGF)1190 StatID Biological Abstracts 2021-02-03 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2021-02-03 Nationallizenz StatID:(DE-HGF)0420 StatID 2022-11-26 ger JCR StatID:(DE-HGF)0100 StatID FORTSCHR NEUROL PSYC : 2021 2022-11-26 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-26 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-26 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-26 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-26 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2022-11-26 DBCoverage StatID:(DE-HGF)1110 StatID Current Contents - Clinical Medicine 2022-11-26 IF < 5 StatID:(DE-HGF)9900 StatID 2022-11-26 I:(DE-2719)1110002 AG Höglinger 1 Translational Neurodegeneration 0 I:(DE-2719)1111015 AG Höglinger 2 Coordinator of Clinical Parkinson Research 1 I:(DE-2719)1111016 Clinical Dementia Research München Clinical Dementia Research München 2 journal VDB I:(DE-2719)1110002 I:(DE-2719)1111015 I:(DE-2719)1111016 UNRESTRICTED