164427 20230915094047.0 10.1016/j.neubiorev.2020.07.015 doi pmid:32687884 pmid 0149-7634 ISSN 1873-7528 ISSN altmetric:86337740 altmetric DZNE-2022-00979 English 610 Spijker, Sabine 0 Incubation of depression: ECM assembly and parvalbumin interneurons after stress. Amsterdam [u.a.] 2020 Elsevier Science article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1685012127_32153 PUB:(DE-HGF) Review Article ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote (CC-BY 4.0) The extracellular space is occupied by a complex network of proteins creating a mesh-like assembly known as the extracellular matrix (ECM). ECM assembles into dense net-like structures, perineuronal nets (PNNs), that envelope cell somas and proximal neurites of predominantly parvalbumin+-(PV+) interneurons. ECM regulates cell-to-cell communication, thereby modulating neuronal network function. Accumulating evidence points to the importance of network dysfunction in the pathophysiology of psychiatric diseases, in which stress acts as a major predisposing factor. Here we review stress-induced changes in ECM/PNNs and PV+-interneurons in preclinical models of (or for) depression, with a special focus on social stress. We argue that the direction of these alterations largely depends on stress recency, as well as on stress timing and the brain region under investigation. A biphasic temporal regulation of ECM/PNNs and PV+-interneuron function is typically observed after stress. Understanding the complex mechanisms underlying ECM organization in relation to stress-induced molecular, cellular and network changes is crucial to further decipher the implications of ECM remodeling in the incubation of depressive symptoms. 899 - ohne Topic (POF4-899) G:(DE-HGF)POF4-899 POF4-899 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de Chronic mild/unpredictable stress Other Early life stress Other Experience-dependent plasticity Other Hippocampus Other Hyper-excitability Other Hypo-excitability Other Prefrontal cortex Other Restraint stress Other Social defeat stress Other Parvalbumins NLM Chemicals Depression MeSH Extracellular Matrix MeSH Interneurons MeSH Neurons MeSH Parvalbumins MeSH Koskinen, Maija-Kreetta 1 Riga, Danai P:(DE-2719)2812662 2 Last author dzne 10.1016/j.neubiorev.2020.07.015 Vol. 118, p. 65 - 79 PERI:(DE-600)1498433-7 65 - 79 Neuroscience & biobehavioral reviews 118 2020 0149-7634 OpenAccess http://pub.dzne.de/record/164427/files/DZNE-2022-00979.pdf OpenAccess pdfa http://pub.dzne.de/record/164427/files/DZNE-2022-00979.pdf?subformat=pdfa oai:pub.dzne.de:164427 openaire open_access VDB driver dnbdelivery Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2812662 DE-HGF Programmungebundene Forschung ohne Programm G:(DE-HGF)POF4-890 G:(DE-HGF)POF4-899 G:(DE-HGF)POF4 G:(DE-HGF)POF4-800 G:(DE-HGF)POF ohne Topic 0 2020 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2021-01-31 Creative Commons Attribution CC BY 4.0 LIC:(DE-HGF)CCBY4 HGFVOC WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2021-01-31 OpenAccess StatID:(DE-HGF)0510 StatID Nationallizenz StatID:(DE-HGF)0420 StatID 2022-11-09 ger DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-09 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-09 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-09 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2022-11-09 DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - Life Sciences 2022-11-09 DBCoverage StatID:(DE-HGF)1120 StatID BIOSIS Reviews Reports And Meetings 2022-11-09 JCR StatID:(DE-HGF)0100 StatID NEUROSCI BIOBEHAV R : 2021 2022-11-09 DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-09 DBCoverage StatID:(DE-HGF)0600 StatID Ebsco Academic Search 2022-11-09 Peer Review StatID:(DE-HGF)0030 StatID ASC 2022-11-09 IF >= 5 StatID:(DE-HGF)9905 StatID NEUROSCI BIOBEHAV R : 2021 2022-11-09 I:(DE-2719)1310007 AG Dityatev Molecular Neuroplasticity 0 journal VDB UNRESTRICTED I:(DE-2719)1310007 FullTexts