257693 20230424163302.0 10.1038/s41380-018-0036-2 doi pmid:29679070 pmid pmc:PMC6195869 pmc 1359-4184 ISSN 1476-5578 ISSN DZNE-2023-00490 English 610 Toda, Tomohisa P:(DE-2719)2814117 0 dzne The role of adult hippocampal neurogenesis in brain health and disease. London 2019 Macmillan article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1682346767_17696 PUB:(DE-HGF) Review Article ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating evidence suggests that adult-born neurons may play distinct physiological roles in hippocampus-dependent functions, such as memory encoding and mood regulation. In addition, several brain diseases, such as neurological diseases and mood disorders, have deleterious effects on adult hippocampal neurogenesis, and some symptoms of those diseases can be partially explained by the dysregulation of adult hippocampal neurogenesis. Here we review a possible link between the physiological functions of adult-born neurons and their roles in pathological conditions. 899 - ohne Topic (POF4-899) G:(DE-HGF)POF4-899 POF4-899 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de Adult MeSH Affect: physiology MeSH Brain: pathology MeSH Brain: physiology MeSH Brain Diseases: pathology MeSH Dentate Gyrus: pathology MeSH Dentate Gyrus: physiology MeSH Hippocampus: metabolism MeSH Hippocampus: pathology MeSH Hippocampus: physiology MeSH Humans MeSH Memory: physiology MeSH Neurogenesis: physiology MeSH Neuronal Plasticity: physiology MeSH Neurons: physiology MeSH Temporal Lobe: pathology MeSH Parylak, Sarah L 1 Linker, Sara B 2 Gage, Fred H 3 10.1038/s41380-018-0036-2 Vol. 24, no. 1, p. 67 - 87 PERI:(DE-600)1502531-7 1 67 - 87 Molecular psychiatry 24 2019 1359-4184 External Institute I:(DE-HGF)0 Extern 0 P:(DE-2719)2814117 DE-HGF Programmungebundene Forschung ohne Programm G:(DE-HGF)POF4-890 G:(DE-HGF)POF4-899 G:(DE-HGF)POF4 G:(DE-HGF)POF4-800 G:(DE-HGF)POF ohne Topic 0 DEAL Springer StatID:(DE-HGF)3002 StatID 2022-11-19 ger DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2022-11-19 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2022-11-19 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2022-11-19 DBCoverage StatID:(DE-HGF)1190 StatID Biological Abstracts 2022-11-19 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2022-11-19 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2022-11-19 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2022-11-19 DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - Life Sciences 2022-11-19 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2022-11-19 JCR StatID:(DE-HGF)0100 StatID MOL PSYCHIATR : 2021 2022-11-19 DBCoverage StatID:(DE-HGF)0600 StatID Ebsco Academic Search 2022-11-19 Peer Review StatID:(DE-HGF)0030 StatID ASC 2022-11-19 IF >= 10 StatID:(DE-HGF)9910 StatID MOL PSYCHIATR : 2021 2022-11-19 journal I:(DE-2719)1710014 I:(DE-2719)1040260 EXTERN4VITA