270712 20240808164239.0 pmid:39044775 pmid 10.1016/j.nbas.2024.100120 doi pmc:PMC11261004 pmc DZNE-2024-00884 610 Mioni, Giovanna 0000-0002-1212-4591 0 Differences between sub-second and supra-second durations for the assessment of timing deficits in amnestic mild cognitive impairment Amsterdam 2024 Elsevier article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1722325628_23665 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Previous studies have often reported timing deficits in older adults with different degrees of cognitive decline, however, the exact nature of impairments in time perception is still to be elucidated. In particular, it is unclear if the deficits are more pronounced for short or long intervals, consistent with notions that different cognitive processes and neuroanatomical areas are involved in the processing of durations of different ranges. The present study aims to further investigate timing abilities in amnestic mild cognitive impairment (aMCI) patients and age-matched controls. Participants were asked to decide whether an acoustic event occurred within the first or the second half of a reference duration. The results revealed a bias towards larger PSE values and reduced precision in aMCI patients compared to healthy controls. Further analyses showed that the bias towards larger PSE values correlated with memory performance, especially when sub-second durations were tested. Overall, the results demonstrate that memory deficits in aMCI patients coincide with changes in time perception in the sub-second interval range. 353 - Clinical and Health Care Research (POF4-353) G:(DE-HGF)POF4-353 POF4-353 POF IV 0 Dataset connected to CrossRef, Journals: pub.dzne.de Aging Other Cognitive decline Other Mild cognitive impairment Other Short-long temporal intervals Other Time perception Other Wolbers, Thomas P:(DE-2719)2810583 1 dzne Riemer, Martin P:(DE-2719)2813753 2 Last author dzne 10.1016/j.nbas.2024.100120 Vol. 6, p. 100120 - PERI:(DE-600)3062875-1 100120 Aging brain 6 2024 2589-9589 OpenAccess http://pub.dzne.de/record/270712/files/DZNE-2024-00884.pdf OpenAccess pdfa http://pub.dzne.de/record/270712/files/DZNE-2024-00884.pdf?subformat=pdfa oai:pub.dzne.de:270712 openaire open_access VDB driver dnbdelivery Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 1 P:(DE-2719)2810583 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2813753 DE-HGF Gesundheit Neurodegenerative Diseases G:(DE-HGF)POF4-350 G:(DE-HGF)POF4-353 G:(DE-HGF)POF4 G:(DE-HGF)POF4-300 G:(DE-HGF)POF Clinical and Health Care Research 0 2024 Creative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0 LIC:(DE-HGF)CCBYNCND4 HGFVOC DBCoverage StatID:(DE-HGF)0501 StatID DOAJ Seal 2023-05-09T12:01:05Z DBCoverage StatID:(DE-HGF)0500 StatID DOAJ 2023-05-09T12:01:05Z OpenAccess StatID:(DE-HGF)0510 StatID Peer Review StatID:(DE-HGF)0030 StatID DOAJ : Anonymous peer review 2023-05-09T12:01:05Z Article Processing Charges StatID:(DE-HGF)0561 StatID 2023-08-23 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2023-08-23 DBCoverage StatID:(DE-HGF)0320 StatID PubMed Central 2023-08-23 Fees StatID:(DE-HGF)0700 StatID 2023-08-23 I:(DE-2719)1310002 AG Wolbers Aging, Cognition and Technology 0 journal VDB UNRESTRICTED I:(DE-2719)1310002 FullTexts