285914 20260407155952.0 10.1002/mrm.70266 doi pmid:41588662 pmid pmc:PMC13049268 pmc 1522-2594 ISSN 0740-3194 ISSN DZNE-2026-00360 English 610 Löwen, Daniel P:(DE-2719)9001317 0 First author Calibration-Free GRAPE pTx Pulses for Homogeneous Spatial-Selective Excitation at 7T. New York, NY [u.a.] 2026 Wiley-Liss article DRIVER Output Types/Journal article DataCite Journal Article journal journal PUB:(DE-HGF)16 1775570296_6266 PUB:(DE-HGF) ARTICLE BibTeX JOURNAL_ARTICLE ORCID Journal Article 0 EndNote Extend the universal pulse GRAPE formalism to pulses with a defined spectral response, and apply the concept to spatial selection.We added Bloch simulations at several frequencies for each voxel to the pulse calculation to create universal spectrally-selective GRAPE pulses. With a superimposed constant gradient field spatial selection was achieved. The method was tested in slice- and slab-selective imaging experiments.Universal spatially-selective GRAPE pulses increased FA homogeneity and SNR. In 2D gradient echoes, the SNR could be increased by approximately 6% compared to CP pulses, and in a slab-selective TSE sequence, the SNR increased by 29% against k T -spokes pulses. Additionally, the slab-selective GRAPE pulse proved to be more robust against B 0 deviations and is significantly shorter in comparison to k T -spokes pulses while maintaining a similar FA homogeneity.Spatially-selective universal GRAPE pulses exhibit superior performance compared to k T -spokes pulses. These short and robust pTx pulses hold potential for enhancing a wide range of imaging applications, thereby advancing 7T MRI technology closer to clinical use. 354 - Disease Prevention and Healthy Aging (POF4-354) G:(DE-HGF)POF4-354 POF4-354 POF IV 0 Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de GRAPE Other parallel transmission Other ultra‐high field Other universal pulses Other Phantoms, Imaging MeSH Humans MeSH Algorithms MeSH Magnetic Resonance Imaging: methods MeSH Signal-To-Noise Ratio MeSH Calibration MeSH Image Processing, Computer-Assisted: methods MeSH Computer Simulation MeSH Brain: diagnostic imaging MeSH Pracht, Eberhard D P:(DE-2719)2810559 1 Veldmann, Marten P:(DE-2719)2814200 2 Gras, Vincent 0000-0002-4997-2738 3 Mauconduit, Franck P:(DE-2719)9002043 4 Boulant, Nicolas 0000-0003-2144-2484 5 Stöcker, Tony P:(DE-2719)2810538 6 Last author 10.1002/mrm.70266 Vol. 95, no. 6, p. 3104 - 3115 PERI:(DE-600)1493786-4 6 3104 - 3115 Magnetic resonance in medicine 95 2026 1522-2594 http://pub.dzne.de/record/285914/files/DZNE-2026-00360.pdf Restricted http://pub.dzne.de/record/285914/files/DZNE-2026-00360.pdf?subformat=pdfa pdfa Restricted Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 0 P:(DE-2719)9001317 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 1 P:(DE-2719)2810559 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 2 P:(DE-2719)2814200 Deutsches Zentrum für Neurodegenerative Erkrankungen I:(DE-588)1065079516 DZNE 6 P:(DE-2719)2810538 DE-HGF Gesundheit Neurodegenerative Diseases G:(DE-HGF)POF4-350 G:(DE-HGF)POF4-354 G:(DE-HGF)POF4 G:(DE-HGF)POF4-300 G:(DE-HGF)POF Disease Prevention and Healthy Aging 0 Nationallizenz StatID:(DE-HGF)0420 StatID 2025-11-11 ger DEAL Wiley StatID:(DE-HGF)3001 StatID 2025-11-11 ger DBCoverage StatID:(DE-HGF)0200 StatID SCOPUS 2025-11-11 DBCoverage StatID:(DE-HGF)0300 StatID Medline 2025-11-11 DBCoverage StatID:(DE-HGF)0199 StatID Clarivate Analytics Master Journal List 2025-11-11 DBCoverage StatID:(DE-HGF)1110 StatID Current Contents - Clinical Medicine 2025-11-11 DBCoverage StatID:(DE-HGF)1190 StatID Biological Abstracts 2025-11-11 DBCoverage StatID:(DE-HGF)0160 StatID Essential Science Indicators 2025-11-11 WoS StatID:(DE-HGF)0113 StatID Science Citation Index Expanded 2025-11-11 DBCoverage StatID:(DE-HGF)0150 StatID Web of Science Core Collection 2025-11-11 DBCoverage StatID:(DE-HGF)1030 StatID Current Contents - Life Sciences 2025-11-11 DBCoverage StatID:(DE-HGF)1050 StatID BIOSIS Previews 2025-11-11 JCR StatID:(DE-HGF)0100 StatID MAGN RESON MED : 2022 2025-11-11 IF < 5 StatID:(DE-HGF)9900 StatID 2025-11-11 I:(DE-2719)1013026 AG Stöcker MR Physics 0 journal EDITORS VDBINPRINT I:(DE-2719)1013026 UNRESTRICTED