Contribution to a book

With aging societies, the incidence and prevalence of dementia are increasing rapidly and will continue to do so worldwide in the next years and decades. It is now possible to diagnose dementia at an early stage using neuropsychological tests and biomarker studies, including imaging (MRI, PET), cerebrospinal fluid analysis, and genetic testing. [...]

Focal Cortical Dysplasia (FCD) is a leading cause of drug-resistant focal epilepsy, and its identification on Magnetic Resonance Imaging (MRI) can enable potentially curative surgical treatment. FCD features are often subtle and heterogeneous and current deep learning models for automated detection exhibit limited sensitivity. [...]

Magnetic resonance imaging (MRI) inherently suffers from noise, which limits downstream medical analyses. In MRI, noise-free images are unobtainable; therefore, existing denoising approaches formulate surrogate training objectives, compromising between preserving detail and concealing noise, causing domain shifts or incomplete denoising. [...]

When navigating, humans and other species rely on landmarks and on self-motion cues to infer their position in space. It is suggested that in cue-integration processes, reliable cues are highly weighed, compared to less reliable ones. [...]

Aggregation of Tau, a microtubule-associated protein, is a hallmark of multiple neurodegenerative disorders collectively termed tauopathies, which include dementia-related diseases like Alzheimer’s disease. Technological advances in genetic engineering have transformed the way we study biology, offering powerful tools to explore fundamental processes and to recapitulate aspects of human disease in animal models in remarkably short time frames. [...]

Introduction: The growing number of elderly people in the populationis accompanied by an increased prevalence of chronic diseases, e.g.dementia, which will confront the healthcare system with majorchallenges in the future. Therefore, appropriate interventions are neededto support healthy aging combined with a high quality of life. [...]

Experimental research on cognition needs more realistic paradigms to achieve ecological validity as wellas to transfer and eventually generalize the results to clinical practice. Selective attention was found to behighly related to memory and training of attentional filtering enhanced memory performance. [...]

Die Frontotemporale Demenz ist eine von sehr unterschiedlichen früh beginnenden und seltenen Demenzformen, die die betroffenen Menschen und ihre Familien oft unerwartet und radikal vor große, das Leben verändernde Herausforderungen stellt. Trotz zunehmender Forschungsaktivitäten und Aufmerksamkeit in der Fachöffentlichkeit für die Lebenssituation von Menschen mit Demenz jenseits der Alzheimer-Symptomatik gibt es eine Reihe von Versorgungslücken, die es zu schließen gilt. [...]

Materielle Armut als kulturelles Phänomen in den Blick zu nehmen, erweitert die Erkenntnismöglichkeiten der psychologischen und soziologischen Armutsforschung. Der Beitrag erläutert, wie das Phänomen Armut kulturpsychologisch in den Blick genommen werden kann. [...]

Demenz ist eine der vorrangigen Ursachen für Einschränkungen im täglichen Leben und Pflegebedürftigkeit bei älteren Menschen weltweit. Menschen mit Demenz leben meist nicht in einer Pflegeeinrichtung, sondern werden in ihrer eigenen Häuslichkeit unterstützt und gepflegt. [...]