Documents in Process

Many reports on adverse effects related to positive gastrointestinal (GI) contrast media (CM) predate 2000; therefore, a literature review on their current safety profile was warranted. This article reviews the literature and updates the Contrast Media Safety Committee guidelines of the European Society of Urogenital Radiology on the safety of positive GI iodine-based and barium sulphate-based CM. [...]

As complex individualized behaviors in mice arise even when genes and environment are held constant, emerging social group structures should also depend on individual behavior. Adult hippocampal neurogenesis drives individual behavior and is involved in certain social behaviors. [...]

Sleep is essential for synaptic homeostasis, a proposed mechanism whereby wakefulness leads to synaptic potentiation and sleep facilitates synaptic down-selection. Synaptic vesicle glycoprotein 2A (SV2A), whose availability is quantifiable by [¹⁸F]SynVesT-1 positron emission tomography (PET), is commonly interpreted as a proxy for synaptic density. [...]

Friedreich's ataxia (FA) is a rare, autosomal recessive neurodegenerative disease that primarily affects children and adolescents in their transition to adulthood, which is associated with several adverse life events caused by the disease progression. This article aims to describe life events associated with FA and their impact on patient-reported outcomes in pediatric and adult onsets. [...]

Ischemic stroke remains a leading cause of disability and mortality worldwide, with limited acute therapeutic options. Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates endothelial function, vascular integrity, and immune responses, and reduced circulating S1P levels have been reported in ischemic stroke. [...]

Death domain-associated protein (Daxx) is one of the two main H3.3 chaperones in mammalian cells and acts as key repressor of RTEs of viral origin. In present study, we found that Daxx is an IFN-stimulated gene mediating repression of RTEs and IFN-stimulated genes (ISGs) upon inflammatory stimuli in microglia. [...]

Death domain-associated protein (Daxx) is one of the two main H3.3 chaperones in mammalian cells and acts as key repressor of RTEs of viral origin. In the present study, we found that Daxx is an IFN-stimulated gene mediating repression of RTEs and IFN-stimulated genes (ISGs) upon inflammatory stimuli in microglia. [...]

Death domain-associated protein (Daxx) is one of the two main H3.3 chaperones in mammalian cells and acts as key repressor of RTEs of viral origin. In present study, we found that Daxx is an IFN-stimulated gene mediating repression of RTEs and IFN-stimulated genes (ISGs) upon inflammatory stimuli in microglia. [...]

Death domain-associated protein (Daxx) is one of the two main H3.3 chaperones in mammalian cells and acts as key repressor of RTEs of viral origin. In present study, we found that Daxx is an IFN-stimulated gene mediating repression of RTEs and IFN-stimulated genes (ISGs) upon inflammatory stimuli in microglia. [...]

Hemispherotomy is a surgical intervention for severe drug-resistant epilepsy that fully disconnects the lesional brain hemisphere from the rest of the nervous system. This creates a rare opportunity to explore whether consciousness can be sustained without external input. [...]