Documents in Process

COVID-19 is associated with various neurological symptoms. Serum neurofilament light chain (sNfL) is a robust marker for neuroaxonal injury. [...]

Task shielding is an important executive control demand in dual-task performance enabling the segregation of stimulus-response translation processes in each task to minimize between-task interference. Although neuroimaging studies have shown activity in left dorsolateral prefrontal cortex (dlPFC) during various multitasking performances, the specific role of dlPFC in task shielding, and whether non-invasive brain stimulation (NIBS) may facilitate task shielding remains unclear [...]

Input Files for Manuscript 'A pulmonologist’s guide to perform and analyse cross-species single-lung-cell transcriptomic' See https://github.com/GenStatLeipzig/pulmonologists_interspecies_scRNA for details. Manuscript authored by: Peter Pennitz1,2*, Holger Kirsten3*, Vincent D [...]

Objective: To construct an ontology for the outdoor mobility of people with dementia (PwD). The model serves two purposes: (a) as a knowledge base from which to build an assistive technology device describing the mobility of PwD (we call this a situation model); (b) as a codebook for the annotation of the recorded behaviour..

R environments to reproduce the LCM-ATAC-seq analysis in Carraro et al., Cell Reports Methods, 2023. Scripts to reproduce the analyses are available at https://github.com/ccarraro/LCM-ATAC-seq [...]

There are currently 50 million people worldwide living with dementia, a number which will triple by 2050. To counteract this development, the focus has shifted to modifying risk factors that could reduce the number of people with dementia [...]

Large-scale brain networks undergo widespread changes with older age and in neurodegenerative diseases such as Alzheimer's disease (AD). Research in young adults (YA) suggest that the underlying functional architecture of brain networks remains relatively consistent between rest and task states. [...]

The uploaded transcriptome data were obtained from APPswePS1dE9 transgenic mice with a C57BL/6J background (APPPS1) and related control animals. The APPPS1 Alzheimer mouse line carries a human APP with Swedish double mutation (APPswe) cointegrated with human PS1 with exon 9 deletion (PS1dE). [...]

Headache is one of the most common neurological manifestations of COVID-19, but it is unclear whether chronic headache as a symptom of Post-COVID-19 is associated with ongoing CNS damage. We compared cerebrospinal fluid (CSF) levels of markers of CNS damage and inflammation in Post-COVID-19 patients with persistent headache to hospitalized acute COVID-19 patients with neurological symptoms and to non-COVID-19 disease-controls. [...]

(1) Background: to test the diagnostic performance of a fully convolutional neural network-based software prototype for clot detection in intracranial arteries using non-enhanced computed tomography (NECT) imaging data. (2) Methods: we retrospectively identified 85 patients with stroke imaging and one intracranial vessel occlusion. [...]