AG Simons
Molecular Neurobiology
Also known as:AG Simons; Molekulare Neurobiologie
⇧ M DZNE ⇧
Recent Publications
All known publications ...
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Journal Article
Feiten, A. F. (First author)DZNE* ; Dahm, K. (First author)DZNE* ; Schlepckow, K. (First author)DZNE* ; van Lengerich, B. ; Suh, J. H. ; Reifschneider, A. ; Wefers, B.DZNE* ; Bartos, L. M. ; Wind, K.Extern* ; de Weerd, L.DZNE* ; Ulas, T.DZNE* ; De-Domenico, E.DZNE* ; Grundschöttel, P.DZNE* ; Paulusch, S.DZNE* ; Tast, B. ; Honda, T. ; Müller, S. A.DZNE* ; Becker, M.DZNE* ; Khalin, I. ; Ricci, A. ; Liesz, A. ; Brunner, B.DZNE* ; Krenner, C.Extern* ; Buschmann, K.Extern* ; Nuscher, B. ; Spieth, L.DZNE* ; Junker, N.DZNE* ; Berghoff, S. A.DZNE* ; Davis, S. S. ; Neher, J. J.DZNE* ; Wurst, W.DZNE* ; Plesnila, N. ; Lewcock, J. W. ; Simons, M.DZNE* ; Lichtenthaler, S. F.DZNE* ; Di Paolo, G. ; Brendel, M.DZNE* ; Capell, A.DZNE* ; Monroe, K. M. ; Schultze, J. L.DZNE* ; Haass, C. (Last author)DZNE*
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.
Nature Communications 17(1), 2002 (2026) [10.1038/s41467-026-68706-8]2026
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Journal Article
Dereddi, R. R. ; Djannatian, M.DZNE* ; Fiore, F. ; Kalita, D. ; Verkest, C. ; Torres, F. B. ; Möbius, W. ; Khodaie, B. ; Ruhwedel, T. ; Alhalaseh, K. ; Schifferer, M.DZNE* ; Wirth, A. ; Hill, A. ; Ottenheijm, R. ; Patrizi, A. ; Kann, O. ; Lechner, S. G. ; Freichel, M. ; Agarwal, A.
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry.
Neuron 114(4), 699 - 723.e11 (2026) [10.1016/j.neuron.2025.11.009]2026
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Journal Article
Todorov-Völgyi, K. ; González-Gallego, J. ; Müller, S. A.DZNE* ; Todorov, M. I. ; Seker, F. B. ; Frerich, S. ; Cernilogar, F. M. ; Schröger, L. ; Malik, R. ; Cao, J. ; Llovera, G. ; Roth, S. ; Schillinger, U. ; Schifferer, M.DZNE* ; Reyahi, A. ; Crusius, D. ; Pedro, L. D. ; Simons, M.DZNE* ; Carlsson, P. ; Ertürk, A. ; Liesz, A. ; Schotta, G. ; Plesnila, N. ; Lichtenthaler, S. F.DZNE* ; Paquet, D. ; Dichgans, M. (Last author)DZNE*
The stroke risk gene Foxf2 maintains brain endothelial cell function via Tie2 signaling.
Nature neuroscience 29(2), 325 - 336 (2026) [10.1038/s41593-025-02136-5]2026
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Journal Article
de la Rosa, C. ; Kendirli, A. ; Baygün, S. ; Bauernschmitt, F. ; Thomann, A. S. ; Kisioglu, I. ; Beckmann, D. ; Carpentier Solorio, Y. ; Pfaffenstaller, V. ; Tai, Y.-H. ; Mehraein, N. ; Sanchez, P. ; Spieth, L.DZNE* ; Gerdes, L. A. ; Beltran, E. ; Dornmair, K. ; Simons, M.DZNE* ; Peters, A. ; Schmidt-Supprian, M. ; Kerschensteiner, M.
In vivo CRISPR screen reveals regulation of macrophage states in neuroinflammation.
Nature neuroscience 29(2), 493 - 509 (2026) [10.1038/s41593-025-02151-6]2026
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Marth, L. (First author)DZNE* ; Martinez-Murcia, F. J. ; Górriz-Sáez, J.-M. ; et al
Patterns and Trajectories of Behavioral and Neuropsychiatric Symptoms in Frontotemporal Dementia and Primary Progressive Aphasia.
Neurology 106(4), e214510 (2026) [10.1212/WNL.0000000000214510]2026
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Sidorov, I. ; Ogrinc, N. ; Spieth, L.DZNE* ; Kopcil, M. ; Heijink, M. ; Dalebout, H. ; Saher, G. ; Berghoff, S. A.DZNE* ; Siuzdak, G. ; Giera, M.
In-Source Fragmentation Annotation in Sterol Mass Spectrometry Imaging.
Analytical chemistry 98(1), 509 - 518 (2026) [10.1021/acs.analchem.5c05199]2026
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Abstract/Journal Article
Rodríguez-Baz, Í. ; Bernhardt, A. M.DZNE* ; Aldecoa, I. ; Arranz, J. ; Arriola-Infante, J. E. ; Maure-Blesa, L. ; Carmona-Iragui, M. ; Longen, S. ; Trossbach, S. V. ; Giese, A. ; Matthias, T. ; Benejam, B. ; Videla, L. ; Hoyo, L. D. ; Barroeta, I. ; Hernandez, A. S. ; Fernandez, S. ; Vaqué-Alcázar, L. ; Aranha, M. R. ; Morcillo-Nieto, A. O. ; Nübling, G.DZNE* ; Wagemann, O.DZNE* ; Stockbauer, A.DZNE* ; Tondo, M. ; Bejanin, A. ; Lleó, A. ; Alcolea, D. ; Molina, L. ; Fortea, J. ; Levin, J. (Last author)DZNE*
Alpha-Synuclein Pathology in Down Syndrome-Associated Alzheimer's Disease: Insights from Seed Amplification Assay and Neuropathology
2025Alzheimer’s Association International Conference, AAIC 25, TorontoToronto, Canada, 27 Jul 2025 - 31 Jul 20252025-07-272025-07-31
Alzheimer's and dementia 21(S2), e106390 (2025) [10.1002/alz70856_106390]2025
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Abstract/Journal Article
Roemer-Cassiano, S. ; Zhang, S. ; Evangelista, L. ; Dehsarvi, A. ; Klonowksi, M. ; Frontzkowski, L. ; Rauchmann, B.-S.DZNE* ; Steward, A. ; Dewenter, A. ; Biel, D. ; Zhu, Z. ; Hirsch, F. ; Pescoller, J. ; Perneczky, R.DZNE* ; Malpetti, M. ; Palleis, C.DZNE* ; Gnoerich, J.Extern* ; Schöll, M. ; Dichgans, M.DZNE* ; Jäkel, S. ; Höglinger, G. U.DZNE* ; Brendel, M.DZNE* ; Yeo, T. ; Franzmeier, N.
Amyloid‐induced neuronal hyperactivity and ‐metabolism are associated with faster tau accumulation in Alzheimer's Disease
2025Alzheimer’s Association International Conference, AAIC 25, TorontoToronto, Canada, 27 Jul 2025 - 31 Jul 20252025-07-272025-07-31
Alzheimer's and dementia 21(Suppl 2), e099685 (2025) [10.1002/alz70856_099685]2025
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Journal Article
Feng, R. (First author)DZNE* ; Spieth, L.DZNE* ; Liu, L.DZNE* ; Berghoff, S.DZNE* ; Franz, J. ; Liu, Q.DZNE* ; Wang, Z.DZNE* ; Tiwari, V.DZNE* ; Vitale, S.DZNE* ; Frerich, S. ; Florensa, S.DZNE* ; Junker, N.DZNE* ; Huber, L.DZNE* ; Keller, M. ; Müller, C. ; Bracher, F. ; Ge, X. ; Rensen, P. C. N. ; Kooij, G. ; Hosang, L. ; Chornyi, S. ; Dichgans, M.DZNE* ; Gokce, O.DZNE* ; Saher, G. ; Stadelmann, C. ; Giera, M. ; Groh, J.DZNE* ; Simons, M. (Last author)DZNE*
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
Immunity 58(12), 2989 - 3005.e10 (2025) [10.1016/j.immuni.2025.10.003]2025
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Journal Article
Kurz, C. ; Carli, L. ; Guersel, S.DZNE* ; Schrurs, I. ; Jethwa, A. ; Carboni, M. ; Bittner, T. ; Hortsch, S. ; Keeser, D. ; Brendel, M.Extern* ; Burow, L. ; Haeckert, J. ; Koriath, C. A. M. ; Tatò, M. L.Extern* ; Utecht, J. ; Papazov, B. ; Morenas Rodriguez, E.DZNE* ; Pogarell, O. ; Palleis, C.DZNE* ; Weidinger, E.Extern* ; Stöcklein, S.Extern* ; Levin, J.DZNE* ; Höglinger, G.DZNE* ; Rauchmann, B.-S.DZNE* ; Perneczky, R. (Last author)DZNE*
Plasma biomarkers of amyloid, tau & neuroinflammation in Alzheimer's disease and corticobasal syndrome.
Archiv für Psychiatrie und Nervenkrankheiten 275(8), 2255 - 2273 (2025) [10.1007/s00406-025-02013-z]2025
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All known publications ...
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