352
Disease Mechanisms Krankheitsmechanismen
| Grant period | 2021 - 2026 |
| Funding body | Helmholtz Gemeinschaft Deutscher Forschungszentren |
| Categories | Leistungskategorie I ; Topic |
| Identifier | G:(DE-HGF)POF4-352 |
⇧ Neurodegenerative Erkrankungen ⇧
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Dissertation / PhD Thesis
The Role of Afferent Hippocampal to Prefrontal Cortex Projections in a Mouse Model of Alzheimer´s Disease
112 p. (2026) = Dissertation, Rheinische Friedrich-Wilhelms-Universität Bonn, 2026
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Journal Article (Review Article)
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids.
Movement disorders 41(3), 581 - 595 (2026) [10.1002/mds.70167]
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Dataset
Dataset: Multi-omic single-nucleus ATAC-seq + RNA-seq of nuclei from the post-mortem human primary motor cortex from patients with ALS, ALS-FTD, C9ORF72-ALS-FTD and neurologically unaffected controls, v1
Zenodo (2026) [10.5281/zenodo.18370646]
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Dataset
Dataset: Single-nucleus RNA-seq of human post-mortem primary motor cortex (M1) nuclei from ALS-FTD patients, NeuN+ (neuronal) and sorted for TDP-43 low vs. high signal, v1
Zenodo (2026) [10.5281/zenodo.18371193]
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Dataset
Dataset: RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics, v3
Zenodo (2026) [10.5281/zenodo.17598867]
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Dataset
Dataset: Main Figures Tabular Data - The mitochondrial unfolded protein response disrupts neuronal–glial communication and promotes senescence in human microglia (v3)
Zenodo (2026) [10.5281/zenodo.18914510]
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Dataset
Dataset: Supplementary Figures Tabular Data - The mitochondrial unfolded protein response disrupts neuronal–glial communication and promotes senescence in human microglia (v2)
Zenodo (2026) [10.5281/zenodo.18914589]
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Journal Article
Molecular Modulation of the Crosstalk Between TDP-43 and SOD1.
International journal of molecular sciences 27(8), 3409 (2026) [10.3390/ijms27083409] special issue: "New Therapies and Strategies in the Treatment of Neurodegenerative Diseases"
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Journal Article
Spinal motoneuron excitability is homeostatically regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice.
Progress in neurobiology 260, 102905 (2026) [10.1016/j.pneurobio.2026.102905]
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Journal Article
Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation.
Nature immunology 27(5), 961 - 974 (2026) [10.1038/s41590-026-02457-y]
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All known publications ...
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