000279184 001__ 279184
000279184 005__ 20250613093344.0
000279184 0247_ $$2doi$$a10.1038/s44220-024-00361-8
000279184 037__ $$aDZNE-2025-00712
000279184 082__ $$a610
000279184 1001_ $$00000-0001-6020-4118$$aBartrés-Faz, David$$b0
000279184 245__ $$aPsychological profiles associated with mental, cognitive and brain health in middle-aged and older adults
000279184 260__ $$aLondon$$bNature Publishing Group UK$$c2025
000279184 3367_ $$2DRIVER$$aarticle
000279184 3367_ $$2DataCite$$aOutput Types/Journal article
000279184 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1749799928_10678
000279184 3367_ $$2BibTeX$$aARTICLE
000279184 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000279184 3367_ $$00$$2EndNote$$aJournal Article
000279184 520__ $$aPsychological characteristics are associated with varying dementia risk and protective factors. To determine whether these characteristics aggregate into psychological profiles and whether these profiles differentially relate to aging health, we conducted a cross-sectional investigation in two independent middle-aged (51.4 ± 7.0 years (mean ± s.d.); N = 750) and older adult (71.1 ± 5.9 years; N = 282) cohorts, supplemented by longitudinal analyses in the former. Using a person-centered approach, three profiles emerged in both cohorts: those with low protective characteristics (profile 1), high risk characteristics (profile 2) and well-balanced characteristics (profile 3). Profile 1 showed the worst objective cognition in older age and middle age (at follow-up), and most rapid cortical thinning. Profile 2 exhibited the worst mental health symptomology and lowest sleep quality in both older age and middle age. We identified profile-dependent divergent patterns of associations that may suggest two distinct paths for mental, cognitive and brain health, emphasizing the need for comprehensive psychological assessments in dementia prevention research to identify groups for more personalized behavior-change strategies.
000279184 536__ $$0G:(DE-HGF)POF4-899$$a899 - ohne Topic (POF4-899)$$cPOF4-899$$fPOF IV$$x0
000279184 588__ $$aDataset connected to CrossRef, Journals: pub.dzne.de
000279184 7001_ $$00000-0002-7421-7101$$aDemnitz-King, Harriet$$b1
000279184 7001_ $$aCabello-Toscano, María$$b2
000279184 7001_ $$00000-0002-6776-6559$$aVaqué-Alcázar, Lídia$$b3
000279184 7001_ $$aSaunders, Rob$$b4
000279184 7001_ $$00000-0001-7906-934X$$aTouron, Edelweiss$$b5
000279184 7001_ $$aCattaneo, Gabriele$$b6
000279184 7001_ $$aGonneaud, Julie$$b7
000279184 7001_ $$0P:(DE-2719)9002456$$aKlimecki-Lenz, Olga Maria$$b8$$udzne
000279184 7001_ $$aBargalló, Núria$$b9
000279184 7001_ $$aSánchez-Solana, Javier$$b10
000279184 7001_ $$aTormos, José M.$$b11
000279184 7001_ $$00000-0002-4889-7932$$aChételat, Gäel$$b12
000279184 7001_ $$00000-0001-8975-0382$$aPascual-Leone, Álvaro$$b13
000279184 7001_ $$00000-0003-0669-6910$$aMarchant, Natalie L.$$b14
000279184 7001_ $$aAndré, Claire$$b15
000279184 7001_ $$aBachelet, Romain$$b16
000279184 7001_ $$aBaez Lugo, Sebastian$$b17
000279184 7001_ $$aChocat, Anne$$b18
000279184 7001_ $$aCollette, Fabienne$$b19
000279184 7001_ $$aColl-Padros, Nina$$b20
000279184 7001_ $$aDautricourt, Sophie$$b21
000279184 7001_ $$aDe La Sayette, Vincent$$b22
000279184 7001_ $$aDelarue, Marion$$b23
000279184 7001_ $$aFerrand Devouge, Eglantine$$b24
000279184 7001_ $$aFrison, Eric$$b25
000279184 7001_ $$aGoldet, Karine$$b26
000279184 7001_ $$0P:(DE-2719)2000032$$aJessen, Frank$$b27$$udzne
000279184 7001_ $$aKrolak-Salmon, Pierre$$b28
000279184 7001_ $$0P:(DE-2719)9002169$$aKuhn, Elizabeth$$b29$$udzne
000279184 7001_ $$aLandeau, Brigitte$$b30
000279184 7001_ $$aLefranc, Valérie$$b31
000279184 7001_ $$aLutz, Antoine$$b32
000279184 7001_ $$aMezenge, Florence$$b33
000279184 7001_ $$0P:(DE-2719)9000940$$aMeiberth, Dix$$b34$$udzne
000279184 7001_ $$aMichel, Laurence$$b35
000279184 7001_ $$aMolinuevo, José Luis$$b36
000279184 7001_ $$aOurry, Valentin$$b37
000279184 7001_ $$aPoisnel, Géraldine$$b38
000279184 7001_ $$aQuillard, Anne$$b39
000279184 7001_ $$aRauchs, Géraldine$$b40
000279184 7001_ $$aSalmon, Eric$$b41
000279184 7001_ $$aSchild, Ann-Katrin$$b42
000279184 7001_ $$aSchimmer, Corinne$$b43
000279184 7001_ $$aSmagghe, Delphine$$b44
000279184 7001_ $$aSmith, Rhonda$$b45
000279184 7001_ $$aSchlosser, Marco$$b46
000279184 7001_ $$aVuilleumier, Patrik$$b47
000279184 7001_ $$aWallet, Cédrick$$b48
000279184 7001_ $$aWalker, Zuzana$$b49
000279184 7001_ $$aWhitfield, Tim$$b50
000279184 7001_ $$0P:(DE-2719)2814122$$aWirth, Miranka$$b51$$udzne
000279184 773__ $$0PERI:(DE-600)3123130-5$$a10.1038/s44220-024-00361-8$$gVol. 3, no. 1, p. 92 - 103$$n1$$p92 - 103$$tNature Mental Health$$v3$$x2731-6076$$y2025
000279184 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9002456$$aExternal Institute$$b8$$kExtern
000279184 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)2000032$$aExternal Institute$$b27$$kExtern
000279184 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9002169$$aExternal Institute$$b29$$kExtern
000279184 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9000940$$aExternal Institute$$b34$$kExtern
000279184 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)2814122$$aExternal Institute$$b51$$kExtern
000279184 9131_ $$0G:(DE-HGF)POF4-899$$1G:(DE-HGF)POF4-890$$2G:(DE-HGF)POF4-800$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vohne Topic$$x0
000279184 915__ $$0StatID:(DE-HGF)3003$$2StatID$$aDEAL Nature$$d2024-12-20$$wger
000279184 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-20
000279184 9801_ $$aEXTERN4VITA
000279184 980__ $$ajournal
000279184 980__ $$aEDITORS
000279184 980__ $$aI:(DE-2719)1011102
000279184 980__ $$aI:(DE-2719)1710011