guest ::
| Home > External Publications > Vita Publications > Psychological profiles associated with mental, cognitive and brain health in middle-aged and older adults > print |
| Home > External Publications > Vita Publications > Psychological profiles associated with mental, cognitive and brain health in middle-aged and older adults > print |
| 001 | 279184 | ||
| 005 | 20250613093344.0 | ||
| 024 | 7 | _ | |a 10.1038/s44220-024-00361-8 |2 doi |
| 037 | _ | _ | |a DZNE-2025-00712 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Bartrés-Faz, David |0 0000-0001-6020-4118 |b 0 |
| 245 | _ | _ | |a Psychological profiles associated with mental, cognitive and brain health in middle-aged and older adults |
| 260 | _ | _ | |a London |c 2025 |b Nature Publishing Group UK |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1749799928_10678 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Psychological characteristics are associated with varying dementia risk and protective factors. To determine whether these characteristics aggregate into psychological profiles and whether these profiles differentially relate to aging health, we conducted a cross-sectional investigation in two independent middle-aged (51.4 ± 7.0 years (mean ± s.d.); N = 750) and older adult (71.1 ± 5.9 years; N = 282) cohorts, supplemented by longitudinal analyses in the former. Using a person-centered approach, three profiles emerged in both cohorts: those with low protective characteristics (profile 1), high risk characteristics (profile 2) and well-balanced characteristics (profile 3). Profile 1 showed the worst objective cognition in older age and middle age (at follow-up), and most rapid cortical thinning. Profile 2 exhibited the worst mental health symptomology and lowest sleep quality in both older age and middle age. We identified profile-dependent divergent patterns of associations that may suggest two distinct paths for mental, cognitive and brain health, emphasizing the need for comprehensive psychological assessments in dementia prevention research to identify groups for more personalized behavior-change strategies. |
| 536 | _ | _ | |a 899 - ohne Topic (POF4-899) |0 G:(DE-HGF)POF4-899 |c POF4-899 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, Journals: pub.dzne.de |
| 700 | 1 | _ | |a Demnitz-King, Harriet |0 0000-0002-7421-7101 |b 1 |
| 700 | 1 | _ | |a Cabello-Toscano, María |b 2 |
| 700 | 1 | _ | |a Vaqué-Alcázar, Lídia |0 0000-0002-6776-6559 |b 3 |
| 700 | 1 | _ | |a Saunders, Rob |b 4 |
| 700 | 1 | _ | |a Touron, Edelweiss |0 0000-0001-7906-934X |b 5 |
| 700 | 1 | _ | |a Cattaneo, Gabriele |b 6 |
| 700 | 1 | _ | |a Gonneaud, Julie |b 7 |
| 700 | 1 | _ | |a Klimecki-Lenz, Olga Maria |0 P:(DE-2719)9002456 |b 8 |u dzne |
| 700 | 1 | _ | |a Bargalló, Núria |b 9 |
| 700 | 1 | _ | |a Sánchez-Solana, Javier |b 10 |
| 700 | 1 | _ | |a Tormos, José M. |b 11 |
| 700 | 1 | _ | |a Chételat, Gäel |0 0000-0002-4889-7932 |b 12 |
| 700 | 1 | _ | |a Pascual-Leone, Álvaro |0 0000-0001-8975-0382 |b 13 |
| 700 | 1 | _ | |a Marchant, Natalie L. |0 0000-0003-0669-6910 |b 14 |
| 700 | 1 | _ | |a André, Claire |b 15 |
| 700 | 1 | _ | |a Bachelet, Romain |b 16 |
| 700 | 1 | _ | |a Baez Lugo, Sebastian |b 17 |
| 700 | 1 | _ | |a Chocat, Anne |b 18 |
| 700 | 1 | _ | |a Collette, Fabienne |b 19 |
| 700 | 1 | _ | |a Coll-Padros, Nina |b 20 |
| 700 | 1 | _ | |a Dautricourt, Sophie |b 21 |
| 700 | 1 | _ | |a De La Sayette, Vincent |b 22 |
| 700 | 1 | _ | |a Delarue, Marion |b 23 |
| 700 | 1 | _ | |a Ferrand Devouge, Eglantine |b 24 |
| 700 | 1 | _ | |a Frison, Eric |b 25 |
| 700 | 1 | _ | |a Goldet, Karine |b 26 |
| 700 | 1 | _ | |a Jessen, Frank |0 P:(DE-2719)2000032 |b 27 |u dzne |
| 700 | 1 | _ | |a Krolak-Salmon, Pierre |b 28 |
| 700 | 1 | _ | |a Kuhn, Elizabeth |0 P:(DE-2719)9002169 |b 29 |u dzne |
| 700 | 1 | _ | |a Landeau, Brigitte |b 30 |
| 700 | 1 | _ | |a Lefranc, Valérie |b 31 |
| 700 | 1 | _ | |a Lutz, Antoine |b 32 |
| 700 | 1 | _ | |a Mezenge, Florence |b 33 |
| 700 | 1 | _ | |a Meiberth, Dix |0 P:(DE-2719)9000940 |b 34 |u dzne |
| 700 | 1 | _ | |a Michel, Laurence |b 35 |
| 700 | 1 | _ | |a Molinuevo, José Luis |b 36 |
| 700 | 1 | _ | |a Ourry, Valentin |b 37 |
| 700 | 1 | _ | |a Poisnel, Géraldine |b 38 |
| 700 | 1 | _ | |a Quillard, Anne |b 39 |
| 700 | 1 | _ | |a Rauchs, Géraldine |b 40 |
| 700 | 1 | _ | |a Salmon, Eric |b 41 |
| 700 | 1 | _ | |a Schild, Ann-Katrin |b 42 |
| 700 | 1 | _ | |a Schimmer, Corinne |b 43 |
| 700 | 1 | _ | |a Smagghe, Delphine |b 44 |
| 700 | 1 | _ | |a Smith, Rhonda |b 45 |
| 700 | 1 | _ | |a Schlosser, Marco |b 46 |
| 700 | 1 | _ | |a Vuilleumier, Patrik |b 47 |
| 700 | 1 | _ | |a Wallet, Cédrick |b 48 |
| 700 | 1 | _ | |a Walker, Zuzana |b 49 |
| 700 | 1 | _ | |a Whitfield, Tim |b 50 |
| 700 | 1 | _ | |a Wirth, Miranka |0 P:(DE-2719)2814122 |b 51 |u dzne |
| 773 | _ | _ | |a 10.1038/s44220-024-00361-8 |g Vol. 3, no. 1, p. 92 - 103 |0 PERI:(DE-600)3123130-5 |n 1 |p 92 - 103 |t Nature Mental Health |v 3 |y 2025 |x 2731-6076 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 8 |6 P:(DE-2719)9002456 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 27 |6 P:(DE-2719)2000032 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 29 |6 P:(DE-2719)9002169 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 34 |6 P:(DE-2719)9000940 |
| 910 | 1 | _ | |a External Institute |0 I:(DE-HGF)0 |k Extern |b 51 |6 P:(DE-2719)2814122 |
| 913 | 1 | _ | |a DE-HGF |b Programmungebundene Forschung |l ohne Programm |1 G:(DE-HGF)POF4-890 |0 G:(DE-HGF)POF4-899 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-800 |4 G:(DE-HGF)POF |v ohne Topic |x 0 |
| 915 | _ | _ | |a DEAL Nature |0 StatID:(DE-HGF)3003 |2 StatID |d 2024-12-20 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2024-12-20 |
| 980 | 1 | _ | |a EXTERN4VITA |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a EDITORS |
| 980 | _ | _ | |a I:(DE-2719)1011102 |
| 980 | _ | _ | |a I:(DE-2719)1710011 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|