Datasets

Several prior studies have proposed the involvement of various brain regions and cell types in Parkinson's disease (PD) pathology. Here, we performed snRNA-seq on the prefrontal cortex and anterior cingulate regions from post-mortem control and PD brain tissue. [...]

Training checkpoints for HypVINN (https://github.com/Deep-MI/FastSurfer) - please cite the paper when using this resource (https://doi.org/10.1162/imag_a_00034). Abstract The hypothalamus plays a crucial role in the regulation of a broad range of physiological, behavioral, and cognitive functions. [...]

This data repository contains an example of the acquired MRI sequences and the output of the post-processing pipelines in the Rhineland Study. An overview and information about the MRI sequences and post-processing pipelines can be found in our work 'Versatile MRI Acquisition and Processing Protocol for Population-Based Neuroimaging.' (under-submission)

Dataset used in a paper 'Using temperature coefficients to support resonance assignment of intrinsically disordered proteins' by Paulina Putko, Javier Agustin Romero, Christian F. Pantoja, Markus Zweckstetter, Krzysztof Kazimierczuk, and Anna Zawadzka-Kazimierczuk [...]

To obtain a general TR catalog across the human genome, we identified genomic intervals with a stretch of exact repetitions of a DNA motif ranging from 1-6bp on GRCh38 autosomes and sex chromosomes by using STRfinder (v1.0). To end up, we successfully found 1,233,959 TR intervals, covering 0.783306% (34 Mbp) of GRCh38 (https://console.cloud.google.com/storage/browser/_details/genomics-public-data/resources/broad/hg38/v0/Homo_sapiens_assembly38.fasta)..

To obtain a general TR catalog across the human genome, we identified genomic intervals with a stretch of exact repetitions of a DNA motif ranging from 1-6bp on GRCh38 autosomes and sex chromosomes by using STRfinder (v1.0), and each STR region was annotated based on gencode.V38 (https://www.gencodegenes.org/human/release_38.html). To end up, we successfully found 1,233,959 TR intervals, covering 0.783306% (34 Mbp) of GRCh38 (https://console.cloud.google.com/storage/browser/_details/genomics-public-data/resources/broad/hg38/v0/Homo_sapiens_assembly38.fasta)..

Repository for the datasets, code, and images underlying figures in the manuscript 'Combined expansion and STED microscopy reveals altered fingerprints of postsynaptic nanostructure across brain regions in ASD-related SHANK3-deficiency'. The folder structure is organized according to associated figures: Figure_NHSE-EF (Figures 1/S1), Figure_SYNLOC (Figure 2/S2-S3), Figure_REGSHAPE-SH3SHAPE (Figure 3/S4-S8), Figure_SH3STED (Figure 4-5/S9-S14), Figure_S15. [...]

Background: Participation in multimodal leisure activities, such as playing a musical instrument, may be protective against brain aging and dementia in older adults (OA). Potential neuroprotective correlates underlying musical activity remain unclear.Objective: This cross-sectional study investigated the association between lifetime musical activity and resting-state functional connectivity (RSFC) in three higher-order brain networks: the Default Mode, Fronto-Parietal, and Salience networks.Methods: We assessed 130 cognitively unimpaired participants (≥ 60 years) from the baseline cohort of the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. [...]

Raw data (.brw) was recorded with BrainWave SW and detected LFP events stored in (.bxr) for SD and ENR groups. These extracellular recordings were obtained from acute hippocampal-cortical slices and were collected at 14KHz/electrode sampling frequency..

Training checkpoints for FastSurferVINN (https://github.com/Deep-MI/FastSurfer) - please cite the paper when using this resource (https://doi.org/10.1016/j.neuroimage.2022.118933).Leading neuroimaging studies have pushed 3T MRI acquisition resolutions below 1.0 mm for improved structure definition and morphometry. Yet, only few, time-intensive automated image analysis pipelines have been validated for high-resolution (HiRes) settings. [...]