2023-06-20 15:15 |
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2023-06-20 15:11 |
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2023-06-20 14:53 |
[DZNE-2023-00641]
Journal Article (Review Article)
Huehn, J. ; Beyer, M.-D.
Epigenetic and transcriptional control of Foxp3+ regulatory T cells.
Regulatory T cells (Treg cells) present a unique T-cell lineage that plays a key role for the initiation and maintenance of immunological tolerance. Treg cells are characterized by the expression of the forkhead box transcription factor Foxp3, which acts as a lineage-specifying factor and determines the unique properties of these immunosuppressive cells. [...]
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2023-06-20 11:23 |
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2023-06-20 11:22 |
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2023-06-20 11:21 |
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2023-06-20 11:20 |
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2023-06-20 11:19 |
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2023-06-20 11:18 |
[DZNE-2023-00626]
Journal Article (Review Article)
Capasso, M.
Regulation of immune responses by proton channels.
The identification of the HVCN1 gene, encoding the only mammalian voltage-gated proton channel, prompted a number of studies on how proton channels affect cellular functions. As their expression is mainly restricted to immune cells, it is not surprising that proton channels regulate different aspects of immune responses. [...]
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2023-06-20 11:17 |
[DZNE-2023-00625]
Journal Article
Capasso, M.
Proton channels in non-phagocytic cells of the immune system.
Proton channels are expressed in all cells of the immune system to various degrees. While their function in phagocytic cells, immune cells that engulf bacteria and cell debris for clearance, has been the object of extensive research, the function of proton channels in non-phagocytic cells has remained more elusive until recently. [...]
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