2025-04-07 10:27 |
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2025-04-07 10:21 |
[DZNE-2025-00500]
Journal Article (Review Article)
Karpova, A. ; Hiesinger, P. R. ; Kuijpers, M. ; et al
Neuronal autophagy in the control of synapse function.
Neurons are long-lived postmitotic cells that capitalize on autophagy to remove toxic or defective proteins and organelles to maintain neurotransmission and the integrity of their functional proteome. Mutations in autophagy genes cause congenital diseases, sharing prominent brain dysfunctions including epilepsy, intellectual disability, and neurodegeneration. [...]
OpenAccess: PDF PDF (PDFA);
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2025-04-07 10:19 |
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2025-04-07 10:17 |
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2025-04-07 10:15 |
[DZNE-2025-00497]
Journal Article
Haase, R. ; Pinetz, T. ; Kobler, E. ; et al
Metastasis Detection Using True and Artificial T1-Weighted Postcontrast Images in Brain MRI.
Small lesions are the limiting factor for reducing gadolinium-based contrast agents in brain magnetic resonance imaging (MRI). The purpose of this study was to compare the sensitivity and precision in metastasis detection on true contrast-enhanced T1-weighted (T1w) images and artificial images synthesized by a deep learning method using low-dose images.In this prospective, multicenter study (5 centers, 12 scanners), 917 participants underwent brain MRI between October 2021 and March 2023 including T1w low-dose (0.033 mmol/kg) and full-dose (0.1 mmol/kg) images. [...]
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2025-04-07 10:13 |
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2025-04-07 10:11 |
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2025-04-03 16:38 |
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2025-04-03 16:37 |
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2025-04-03 16:36 |
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