Publications Database

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2025-12-19
15:20

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2025-12-19
15:18
[DZNE-2025-01422] Journal Article
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β-Blocker effects in huntington's disease: A caution on clinical interpretation.
Journal of Huntington's disease Advance online publication, - () [10.1177/18796397251401745]
A recent retrospective analysis of Enroll HD data suggesting β-blockers slow Huntington's disease progression has triggered patient demand but requires caution. The findings rely solely on small observational subsets and are vulnerable to bias and confounding. [...]
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2025-12-18
14:44
[DZNE-2025-01411] Dataset
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Cryo-em structure of the Nup98 fibril polymorph 1 (EMD-13851)
Electron Microscopy Data Bank (EMDB) ()
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2025-12-18
14:42
[DZNE-2025-01410] Dataset
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Cryo-em structure of the Nup98 fibril polymorph 2 (EMD-13852)
Electron Microscopy Data Bank (EMDB) ()
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2025-12-18
14:40
[DZNE-2025-01409] Dataset
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Cryo-em structure of the Nup98 fibril polymorph 4 (EMD-13854)
Electron Microscopy Data Bank (EMDB) ()
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2025-12-17
16:20
[DZNE-2025-01408] Dataset

Dataset: LTBio Pipelines GUI, v1
Zenodo () [10.5281/ZENODO.15632278]

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2025-12-17
16:15
[DZNE-2025-01407] Dataset
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Dataset: RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics, v1
Zenodo () [10.5281/zenodo.17113344]
Amyloids, classically linked to neurodegenerative diseases, also play critical roles in infection and immunity. Phenol-soluble modulins (PSMs) from Staphylococcus aureus are virulent amyloids that contribute to cytotoxicity, immune modulation, and biofilm stability. [...]

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2025-12-17
16:14
[DZNE-2025-01406] Dataset
; ; ; et al
Dataset: RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics, v2
Zenodo () [10.5281/zenodo.17116616]
Amyloids, classically linked to neurodegenerative diseases, also play critical roles in infection and immunity. Phenol-soluble modulins (PSMs) from Staphylococcus aureus are virulent amyloids that contribute to cytotoxicity, immune modulation, and biofilm stability. [...]

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2025-12-17
16:10
[DZNE-2025-01405] Dataset
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Dataset: Chronic Aducanumab-mediated clearance of amyloid plaques decreases microglial activation and induces a unique microglial phenotype associated with antigen presentation
Gene Expression Omnibus ()
Anti-amyloid β-peptide (Aβ) immune therapy was developed as treatment for Alzheimer’s disease (AD) to reduce and prevent amyloid plaque pathology. This approach has proven successful in phase 3 clinical trials of Aducanumab, Lecanemab and Donanemab. [...]
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2025-12-17
16:06
[DZNE-2025-01404] Dataset
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Dataset: MCI Data set
Zenodo () [10.5281/zenodo.17649156]
Embargoed: The files will be made publicly available on November 19, 2035..

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