000136356 001__ 136356 000136356 005__ 20240321220043.0 000136356 0247_ $$2doi$$a10.1007/s10654-011-9624-z 000136356 0247_ $$2pmid$$apmid:22002080 000136356 0247_ $$2pmc$$apmc:PMC3218266 000136356 0247_ $$2ISSN$$a0393-2990 000136356 0247_ $$2ISSN$$a1573-7284 000136356 037__ $$aDZNE-2020-02678 000136356 041__ $$aEnglish 000136356 082__ $$a610 000136356 1001_ $$0P:(DE-HGF)0$$aIkram, M Arfan$$b0$$eCorresponding author 000136356 245__ $$aThe Rotterdam Scan Study: design and update up to 2012. 000136356 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V.$$c2011 000136356 264_1 $$2Crossref$$3online$$bSpringer Science and Business Media LLC$$c2011-10-16 000136356 264_1 $$2Crossref$$3print$$bSpringer Science and Business Media LLC$$c2011-10-01 000136356 3367_ $$2DRIVER$$aarticle 000136356 3367_ $$2DataCite$$aOutput Types/Journal article 000136356 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1607598264_4804 000136356 3367_ $$2BibTeX$$aARTICLE 000136356 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000136356 3367_ $$00$$2EndNote$$aJournal Article 000136356 520__ $$aNeuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 1999 random subsets of the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. We also describe the imaging protocol and post-processing techniques, and highlight the main findings to date. Finally, we make recommendations for future research, which will also be the main focus of investigation in the Rotterdam Scan Study. 000136356 536__ $$0G:(DE-HGF)POF3-345$$a345 - Population Studies and Genetics (POF3-345)$$cPOF3-345$$fPOF III$$x0 000136356 588__ $$aDataset connected to CrossRef, PubMed, 000136356 650_2 $$2MeSH$$aAged 000136356 650_2 $$2MeSH$$aAged, 80 and over 000136356 650_2 $$2MeSH$$aAging: pathology 000136356 650_2 $$2MeSH$$aBrain: blood supply 000136356 650_2 $$2MeSH$$aBrain: pathology 000136356 650_2 $$2MeSH$$aBrain Mapping 000136356 650_2 $$2MeSH$$aChronic Disease 000136356 650_2 $$2MeSH$$aFemale 000136356 650_2 $$2MeSH$$aHumans 000136356 650_2 $$2MeSH$$aImage Interpretation, Computer-Assisted 000136356 650_2 $$2MeSH$$aImage Processing, Computer-Assisted 000136356 650_2 $$2MeSH$$aLongitudinal Studies 000136356 650_2 $$2MeSH$$aMagnetic Resonance Imaging: methods 000136356 650_2 $$2MeSH$$aMale 000136356 650_2 $$2MeSH$$aMiddle Aged 000136356 650_2 $$2MeSH$$aNervous System Diseases: pathology 000136356 650_2 $$2MeSH$$aNetherlands 000136356 650_2 $$2MeSH$$aNeuroimaging 000136356 650_2 $$2MeSH$$aPopulation Surveillance 000136356 650_2 $$2MeSH$$aRisk Factors 000136356 7001_ $$0P:(DE-HGF)0$$avan der Lugt, Aad$$b1 000136356 7001_ $$0P:(DE-HGF)0$$aNiessen, Wiro J$$b2 000136356 7001_ $$0P:(DE-HGF)0$$aKrestin, Gabriel P$$b3 000136356 7001_ $$0P:(DE-HGF)0$$aKoudstaal, Peter J$$b4 000136356 7001_ $$0P:(DE-HGF)0$$aHofman, Albert$$b5 000136356 7001_ $$0P:(DE-2719)2810403$$aBreteler, Monique M B$$b6$$udzne 000136356 7001_ $$0P:(DE-HGF)0$$aVernooij, Meike W$$b7 000136356 77318 $$2Crossref$$3journal-article$$a10.1007/s10654-011-9624-z$$b : Springer Science and Business Media LLC, 2011-10-01$$n10$$p811-824$$tEuropean Journal of Epidemiology$$v26$$x0393-2990$$y2011 000136356 773__ $$0PERI:(DE-600)2004992-4$$a10.1007/s10654-011-9624-z$$gVol. 26, no. 10, p. 811 - 824$$n10$$p811-824$$q26:10<811 - 824$$tEuropean journal of epidemiology$$v26$$x0393-2990$$y2011 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missing cx lookup --$$a10.1038/nn1008$$o10.1038/nn1008 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2007.05.018$$o10.1016/j.neuroimage.2007.05.018 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/S1361-8415(03)00037-9$$o10.1016/S1361-8415(03)00037-9 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.brainresprot.2004.10.001$$o10.1016/j.brainresprot.2004.10.001 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/S0022-510X(01)00667-0$$o10.1016/S0022-510X(01)00667-0 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1161/STROKEAHA.107.493494$$o10.1161/STROKEAHA.107.493494 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2009.01.011$$o10.1016/j.neuroimage.2009.01.011 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1161/STROKEAHA.111.623090$$o10.1161/STROKEAHA.111.623090 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1109/34.969114$$o10.1109/34.969114 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--$$a10.1016/j.neuroimage.2008.07.052$$o10.1016/j.neuroimage.2008.07.052 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2004.07.051$$o10.1016/j.neuroimage.2004.07.051 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2006.02.024$$o10.1016/j.neuroimage.2006.02.024 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2010.12.012$$o10.1016/j.neuroimage.2010.12.012 000136356 999C5 $$2Crossref$$oR Boer de 2010$$y2010 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1093/cercor/bhg087$$o10.1093/cercor/bhg087 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2004.07.016$$o10.1016/j.neuroimage.2004.07.016 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1056/NEJMoa070972$$o10.1056/NEJMoa070972 000136356 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1212/WNL.0b013e3181ae7c5e$$o10.1212/WNL.0b013e3181ae7c5e 000136356 999C5 $$2Crossref$$9-- missing cx lookup 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