%0 Journal Article
%A Teipel, Stefan J
%A Reuter, Sigrid
%A Stieltjes, Bram
%A Acosta-Cabronero, Julio
%A Ernemann, Ulrike
%A Fellgiebel, Andreas
%A Filippi, Massimo
%A Frisoni, Giovanni
%A Hentschel, Frank
%A Jessen, Frank
%A Klöppel, Stefan
%A Meindl, Thomas
%A Pouwels, Petra J W
%A Hauenstein, Karl-Heinz
%A Hampel, Harald
%T Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study.
%J Psychiatry research
%V 194
%N 3
%@ 0925-4927
%C Amsterdam [u.a.]
%I Elsevier Science
%M DZNE-2020-02714
%P 363-371
%D 2011
%X Diffusion tensor imaging (DTI) detects white matter damage in neuro-psychiatric disorders, but data on reliability of DTI measures across more than two scanners are still missing. In this study we assessed multicenter reproducibility of DTI acquisitions based on a physical phantom as well as brain scans across 16 scanners. In addition, we performed DTI scans in a group of 26 patients with clinically probable Alzheimer's disease (AD) and 12 healthy elderly controls at one single center. We determined the variability of fractional anisotropy (FA) measures using manually placed regions of interest as well as automated tract based spatial statistics and deformation based analysis. The coefficient of variation (CV) of FA was 6.9
%K Aged
%K Aged, 80 and over
%K Alzheimer Disease: diagnosis
%K Anisotropy
%K Bias
%K Brain: pathology
%K Brain Mapping
%K Diffusion Tensor Imaging: methods
%K Europe
%K Female
%K Humans
%K Middle Aged
%K Nerve Fibers, Myelinated: pathology
%K Phantoms, Imaging
%K Young Adult
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:22078796
%R 10.1016/j.pscychresns.2011.05.012
%U https://pub.dzne.de/record/136392