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@ARTICLE{Harris:136572,
author = {Harris, Mathew A and Wolbers, Thomas},
title = {{A}geing effects on path integration and landmark
navigation.},
journal = {Hippocampus},
volume = {22},
number = {8},
issn = {1050-9631},
address = {New York, NY [u.a.]},
publisher = {Wiley},
reportid = {DZNE-2020-02894},
pages = {1770-1780},
year = {2012},
abstract = {Navigation abilities show marked decline in both normal
ageing and dementia. Path integration may be particularly
affected, as it is supported by the hippocampus and
entorhinal cortex, both of which show severe degeneration
with ageing. Age differences in path integration based on
kinaesthetic and vestibular cues have been clearly
demonstrated, but very little research has focused on visual
path integration, based only on optic flow. Path integration
is complemented by landmark navigation, which may also show
age differences, but has not been well studied either. Here
we present a study using several simple virtual navigation
tasks to explore age differences in path integration both
with and without landmark information. We report that,
within a virtual environment that provided only optic flow
information, older participants exhibited deficits in path
integration in terms of distance reproduction, rotation
reproduction, and triangle completion. We also report age
differences in triangle completion within an environment
that provided landmark information. In all tasks, we
observed a more restricted range of responses in the older
participants, which we discuss in terms of a leaky
integrator model, as older participants showed greater leak
than younger participants. Our findings begin to explain the
mechanisms underlying age differences in path integration,
and thus contribute to an understanding of the substantial
decline in navigation abilities observed in ageing.},
keywords = {Adult / Aged / Aged, 80 and over / Aging: physiology / Cues
/ Distance Perception: physiology / Entorhinal Cortex:
physiology / Hippocampus: physiology / Humans / Middle Aged
/ Neuropsychological Tests / Orientation: physiology /
Rotation / Space Perception / Task Performance and Analysis
/ User-Computer Interface / Vestibule, Labyrinth: physiology
/ Visual Perception},
cin = {AG Wolbers},
ddc = {610},
cid = {I:(DE-2719)1310002},
pnm = {344 - Clinical and Health Care Research (POF3-344)},
pid = {G:(DE-HGF)POF3-344},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22431367},
doi = {10.1002/hipo.22011},
url = {https://pub.dzne.de/record/136572},
}