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@ARTICLE{Mller:136759,
      author       = {Müller, Notger G and Strumpf, H. and Scholz, M. and Baier,
                      B. and Melloni, L.},
      title        = {{R}epetition suppression versus enhancement--it's quantity
                      that matters.},
      journal      = {Cerebral cortex},
      volume       = {23},
      number       = {2},
      issn         = {1047-3211},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {DZNE-2020-03081},
      pages        = {315-322},
      year         = {2013},
      abstract     = {Upon repetition, certain stimuli induce reduced neural
                      responses (i.e., repetition suppression), whereas others
                      evoke stronger signals (i.e., repetition enhancement). It
                      has been hypothesized that stimulus properties (e.g.,
                      visibility) determine the direction of the repetition
                      effect. Here, we show that the very same stimuli can induce
                      both repetition suppression and enhancement, whereby the
                      only determining factor is the number of repetitions.
                      Repeating the same, initially novel low-visible pictures of
                      scenes for up to 5 times enhanced the blood oxygen
                      level-dependent (BOLD) response in scene-selective areas,
                      that is, the parahippocampal place area (PPA) and the
                      transverse occipital sulcus (TOS), presumably reflecting the
                      strengthening of the internal representation. Additional
                      repetitions (6-9) resulted in progressively attenuated
                      neural responses indicating a more efficient representation
                      of the now familiar stimulus. Behaviorally, repetition led
                      to increasingly faster responses and higher visibility
                      ratings. Novel scenes induced the largest BOLD response in
                      the PPA and also higher activity in yet another
                      scene-selective region, the retrospenial cortex (RSC). We
                      propose that 2 separable processes modulate activity in the
                      PPA: one process optimizes the internal stimulus
                      representation and involves TOS and the other differentiates
                      between familiar and novel scenes and involves RSC.},
      keywords     = {Adolescent / Adult / Brain: physiology / Brain Mapping /
                      Female / Humans / Magnetic Resonance Imaging / Male / Photic
                      Stimulation / Recognition, Psychology: physiology / Young
                      Adult},
      cin          = {AG Müller},
      ddc          = {610},
      cid          = {I:(DE-2719)1310003},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22314047},
      doi          = {10.1093/cercor/bhs009},
      url          = {https://pub.dzne.de/record/136759},
}