guest ::
| Home > Publications Database > Maladaptive bias for extrahippocampal navigation strategies in aging humans. > print |
| Home > Publications Database > Maladaptive bias for extrahippocampal navigation strategies in aging humans. > print |
| 001 | 136867 | ||
| 005 | 20240321220141.0 | ||
| 024 | 7 | _ | |a 10.1523/JNEUROSCI.0717-12.2013 |2 doi |
| 024 | 7 | _ | |a pmid:23554482 |2 pmid |
| 024 | 7 | _ | |a pmc:PMC6618910 |2 pmc |
| 024 | 7 | _ | |a 0270-6474 |2 ISSN |
| 024 | 7 | _ | |a 1529-2401 |2 ISSN |
| 024 | 7 | _ | |a altmetric:1337677 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-03189 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Wiener, Jan M |0 P:(DE-HGF)0 |b 0 |e Corresponding author |
| 245 | _ | _ | |a Maladaptive bias for extrahippocampal navigation strategies in aging humans. |
| 260 | _ | _ | |a Washington, DC |c 2013 |b Soc.57413 |
| 264 | _ | 1 | |3 online |2 Crossref |b Society for Neuroscience |c 2013-04-03 |
| 264 | _ | 1 | |3 print |2 Crossref |b Society for Neuroscience |c 2013-04-03 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1586865389_18506 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Efficient spatial navigation requires not only accurate spatial knowledge but also the selection of appropriate strategies. Using a novel paradigm that allowed us to distinguish between beacon, associative cue, and place strategies, we investigated the effects of cognitive aging on the selection and adoption of navigation strategies in humans. Participants were required to rejoin a previously learned route encountered from an unfamiliar direction. Successful performance required the use of an allocentric place strategy, which was increasingly observed in young participants over six experimental sessions. In contrast, older participants, who were able to recall the route when approaching intersections from the same direction as during encoding, failed to use the correct place strategy when approaching intersections from novel directions. Instead, they continuously used a beacon strategy and showed no evidence of changing their behavior across the six sessions. Given that this bias was already apparent in the first experimental session, the inability to adopt the correct place strategy is not related to an inability to switch from a firmly established response strategy to an allocentric place strategy. Rather, and in line with previous research, age-related deficits in allocentric processing result in shifts in preferred navigation strategies and an overall bias for response strategies. The specific preference for a beacon strategy is discussed in the context of a possible dissociation between beacon-based and associative-cue-based response learning in the striatum, with the latter being more sensitive to age-related changes. |
| 536 | _ | _ | |a 344 - Clinical and Health Care Research (POF3-344) |0 G:(DE-HGF)POF3-344 |c POF3-344 |f POF III |x 0 |
| 542 | _ | _ | |i 2013-10-03 |2 Crossref |u https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 650 | _ | 2 | |a Adaptation, Psychological: physiology |2 MeSH |
| 650 | _ | 2 | |a Adult |2 MeSH |
| 650 | _ | 2 | |a Aged |2 MeSH |
| 650 | _ | 2 | |a Aging |2 MeSH |
| 650 | _ | 2 | |a Association Learning |2 MeSH |
| 650 | _ | 2 | |a Bias |2 MeSH |
| 650 | _ | 2 | |a Cues |2 MeSH |
| 650 | _ | 2 | |a Female |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Male |2 MeSH |
| 650 | _ | 2 | |a Reaction Time: physiology |2 MeSH |
| 650 | _ | 2 | |a Spatial Behavior: physiology |2 MeSH |
| 650 | _ | 2 | |a Young Adult |2 MeSH |
| 700 | 1 | _ | |a de Condappa, Olivier |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Harris, Mathew A |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Wolbers, Thomas |0 P:(DE-2719)2810583 |b 3 |e Last author |
| 773 | 1 | 8 | |a 10.1523/jneurosci.0717-12.2013 |b Society for Neuroscience |d 2013-04-03 |n 14 |p 6012-6017 |3 journal-article |2 Crossref |t The Journal of Neuroscience |v 33 |y 2013 |x 0270-6474 |
| 773 | _ | _ | |a 10.1523/JNEUROSCI.0717-12.2013 |g Vol. 33, no. 14, p. 6012 - 6017 |0 PERI:(DE-600)1475274-8 |n 14 |q 33:14<6012 - 6017 |p 6012-6017 |t The journal of neuroscience |v 33 |y 2013 |x 0270-6474 |
| 856 | 7 | _ | |2 Pubmed Central |u http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618910 |
| 909 | C | O | |p VDB |o oai:pub.dzne.de:136867 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 3 |6 P:(DE-2719)2810583 |
| 913 | 1 | _ | |a DE-HGF |b Forschungsbereich Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-344 |2 G:(DE-HGF)POF3-300 |v Clinical and Health Care Research |x 0 |
| 914 | 1 | _ | |y 2013 |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b J NEUROSCI : 2017 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0320 |2 StatID |b PubMed Central |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0110 |2 StatID |b Science Citation Index |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |
| 915 | _ | _ | |a IF >= 5 |0 StatID:(DE-HGF)9905 |2 StatID |b J NEUROSCI : 2017 |
| 920 | 1 | _ | |0 I:(DE-2719)1310002 |k AG Wolbers |l Aging & Cognition |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)1310002 |
| 980 | _ | _ | |a UNRESTRICTED |
| 999 | C | 5 | |a 10.1038/npp.2009.131 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/S0376-6357(00)00150-9 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1196/annals.1440.002 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1523/JNEUROSCI.19-07-02789.1999 |9 -- missing cx lookup -- |1 Devan |p 2789 - |2 Crossref |t J Neurosci |v 19 |y 1999 |
| 999 | C | 5 | |a 10.1073/pnas.0801489105 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.neuroscience.2005.08.021 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/S0166-4328(03)00218-3 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1002/hipo.20651 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.jchemneu.2003.10.003 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1002/hipo.22011 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/S0896-6273(03)00095-3 |9 -- missing cx lookup -- |1 Hartley |p 877 - |2 Crossref |t Neuron |v 6 |y 2003 |
| 999 | C | 5 | |a 10.1016/j.bbr.2010.01.012 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.bbr.2008.08.040 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1371/journal.pone.0018611 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.euroneuro.2011.03.009 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1002/hipo.10070 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1037/0882-7974.15.1.126 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1037/0882-7974.6.1.128 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1001/archneurol.2009.125 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1002/gps.2101 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/S0163-1047(05)80009-3 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/0306-4522(89)90128-0 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1037/0735-7044.116.5.851 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1093/cercor/bhl036 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1007/PL00007778 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1111/j.1532-5415.2005.53221.x |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1101/lm.64803 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1006/nlme.1996.0007 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1093/cercor/bhi044 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.neurobiolaging.2012.01.052 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1155/2010/108190 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1002/syn.10206 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.neuron.2004.07.009 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.tins.2004.06.006 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.3758/BF03193465 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.3389/fnagi.2012.00007 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1523/JNEUROSCI.4705-04.2005 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1016/j.cogbrainres.2004.06.013 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1146/annurev.pathmechdis.2.010506.092044 |9 -- missing cx lookup -- |2 Crossref |
| 999 | C | 5 | |a 10.1101/lm.81004 |9 -- missing cx lookup -- |2 Crossref |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|