Home > Publications Database > Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology. > print |
001 | 136914 | ||
005 | 20240719165309.0 | ||
024 | 7 | _ | |a 10.1038/jid.2013.43 |2 doi |
024 | 7 | _ | |a pmid:23358095 |2 pmid |
024 | 7 | _ | |a 0022-202X |2 ISSN |
024 | 7 | _ | |a 1523-1747 |2 ISSN |
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037 | _ | _ | |a DZNE-2020-03236 |
041 | _ | _ | |a English |
082 | _ | _ | |a 610 |
100 | 1 | _ | |a Heilmann, Stefanie |b 0 |
245 | _ | _ | |a Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology. |
260 | _ | _ | |a Amsterdam |c 2013 |b Elsevier |
264 | _ | 1 | |3 print |2 Crossref |b Elsevier BV |c 2013-06-01 |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1708431245_6807 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
520 | _ | _ | |a The pathogenesis of androgenetic alopecia (AGA, male-pattern baldness) is driven by androgens, and genetic predisposition is the major prerequisite. Candidate gene and genome-wide association studies have reported that single-nucleotide polymorphisms (SNPs) at eight different genomic loci are associated with AGA development. However, a significant fraction of the overall heritable risk still awaits identification. Furthermore, the understanding of the pathophysiology of AGA is incomplete, and each newly associated locus may provide novel insights into contributing biological pathways. The aim of this study was to identify unknown AGA risk loci by replicating SNPs at the 12 genomic loci that showed suggestive association (5 × 10−8 |
536 | _ | _ | |a 345 - Population Studies and Genetics (POF3-345) |0 G:(DE-HGF)POF3-345 |c POF3-345 |f POF III |x 0 |
542 | _ | _ | |i 2013-06-01 |2 Crossref |u https://www.elsevier.com/tdm/userlicense/1.0/ |
542 | _ | _ | |i 2015-12-02 |2 Crossref |u https://www.elsevier.com/open-access/userlicense/1.0/ |
588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
650 | _ | 7 | |a FZD10 protein, human |2 NLM Chemicals |
650 | _ | 7 | |a Frizzled Receptors |2 NLM Chemicals |
650 | _ | 7 | |a WNT10A protein, human |2 NLM Chemicals |
650 | _ | 7 | |a WNT3 protein, human |2 NLM Chemicals |
650 | _ | 7 | |a WNT6 protein, human |2 NLM Chemicals |
650 | _ | 7 | |a Wnt Proteins |2 NLM Chemicals |
650 | _ | 7 | |a Wnt3 Protein |2 NLM Chemicals |
650 | _ | 7 | |a CYP27A1 protein, human |0 EC 1.14.15.15 |2 NLM Chemicals |
650 | _ | 7 | |a Cholestanetriol 26-Monooxygenase |0 EC 1.14.15.15 |2 NLM Chemicals |
650 | _ | 2 | |a Adult |2 MeSH |
650 | _ | 2 | |a Alopecia: epidemiology |2 MeSH |
650 | _ | 2 | |a Alopecia: etiology |2 MeSH |
650 | _ | 2 | |a Alopecia: genetics |2 MeSH |
650 | _ | 2 | |a Alopecia: metabolism |2 MeSH |
650 | _ | 2 | |a Cholestanetriol 26-Monooxygenase: genetics |2 MeSH |
650 | _ | 2 | |a Chromosomes, Human, Pair 12 |2 MeSH |
650 | _ | 2 | |a Chromosomes, Human, Pair 2 |2 MeSH |
650 | _ | 2 | |a Chromosomes, Human, Pair 3 |2 MeSH |
650 | _ | 2 | |a Chromosomes, Human, Pair 5 |2 MeSH |
650 | _ | 2 | |a European Continental Ancestry Group: genetics |2 MeSH |
650 | _ | 2 | |a European Continental Ancestry Group: statistics & numerical data |2 MeSH |
650 | _ | 2 | |a Frizzled Receptors: genetics |2 MeSH |
650 | _ | 2 | |a Genetic Predisposition to Disease: epidemiology |2 MeSH |
650 | _ | 2 | |a Genetic Predisposition to Disease: genetics |2 MeSH |
650 | _ | 2 | |a Genome-Wide Association Study |2 MeSH |
650 | _ | 2 | |a Humans |2 MeSH |
650 | _ | 2 | |a Male |2 MeSH |
650 | _ | 2 | |a Middle Aged |2 MeSH |
650 | _ | 2 | |a Polymorphism, Single Nucleotide: genetics |2 MeSH |
650 | _ | 2 | |a Risk Factors |2 MeSH |
650 | _ | 2 | |a Wnt Proteins: genetics |2 MeSH |
650 | _ | 2 | |a Wnt Signaling Pathway: physiology |2 MeSH |
650 | _ | 2 | |a Wnt3 Protein: genetics |2 MeSH |
700 | 1 | _ | |a Kiefer, Amy K |b 1 |
700 | 1 | _ | |a Fricker, Nadine |b 2 |
700 | 1 | _ | |a Drichel, Dmitriy |0 P:(DE-2719)2740473 |b 3 |u dzne |
700 | 1 | _ | |a Hillmer, Axel M |b 4 |
700 | 1 | _ | |a Herold, Christine |0 P:(DE-2719)2802016 |b 5 |u dzne |
700 | 1 | _ | |a Tung, Joyce Y |b 6 |
700 | 1 | _ | |a Eriksson, Nicholas |b 7 |
700 | 1 | _ | |a Redler, Silke |b 8 |
700 | 1 | _ | |a Betz, Regina C |b 9 |
700 | 1 | _ | |a Li, Rui |b 10 |
700 | 1 | _ | |a Kárason, Ari |b 11 |
700 | 1 | _ | |a Nyholt, Dale R |b 12 |
700 | 1 | _ | |a Song, Kijoung |b 13 |
700 | 1 | _ | |a Vermeulen, Sita H |b 14 |
700 | 1 | _ | |a Kanoni, Stavroula |b 15 |
700 | 1 | _ | |a Dedoussis, George |b 16 |
700 | 1 | _ | |a Martin, Nicholas G |b 17 |
700 | 1 | _ | |a Kiemeney, Lambertus A |b 18 |
700 | 1 | _ | |a Mooser, Vincent |b 19 |
700 | 1 | _ | |a Stefansson, Kari |b 20 |
700 | 1 | _ | |a Richards, J Brent |b 21 |
700 | 1 | _ | |a Becker, Tim |0 P:(DE-2719)2501867 |b 22 |u dzne |
700 | 1 | _ | |a Brockschmidt, Felix F |b 23 |
700 | 1 | _ | |a Hinds, David A |b 24 |
700 | 1 | _ | |a Nöthen, Markus M |0 P:(DE-HGF)0 |b 25 |e Corresponding author |
773 | 1 | 8 | |a 10.1038/jid.2013.43 |b : Elsevier BV, 2013-06-01 |n 6 |p 1489-1496 |3 journal-article |2 Crossref |t Journal of Investigative Dermatology |v 133 |y 2013 |x 0022-202X |
773 | _ | _ | |a 10.1038/jid.2013.43 |g Vol. 133, no. 6, p. 1489 - 1496 |0 PERI:(DE-600)2006902-9 |n 6 |q 133:6<1489 - 1496 |p 1489-1496 |t The journal of investigative dermatology |v 133 |y 2013 |x 0022-202X |
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