Home > Publications Database > Effects of a cognitive training on spatial learning and associated functional brain activations. > print

001     137003
005     20240522120310.0
024 7 _ |a 10.1186/1471-2202-14-73
|2 doi
024 7 _ |a pmid:23870447
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024 7 _ |a pmc:PMC3729599
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024 7 _ |a altmetric:1637445
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037 _ _ |a DZNE-2020-03325
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Hötting, Kirsten
|0 P:(DE-HGF)0
|b 0
|e Corresponding author
245 _ _ |a Effects of a cognitive training on spatial learning and associated functional brain activations.
260 _ _ |a Heidelberg
|c 2013
|b Springer
264 _ 1 |3 online
|2 Crossref
|b Springer Science and Business Media LLC
|c 2013-07-20
264 _ 1 |3 print
|2 Crossref
|b Springer Science and Business Media LLC
|c 2013-12-01
336 7 _ |a article
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336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a Both cognitive and physical exercise have been discussed as promising interventions for healthy cognitive aging. The present study assessed the effects of cognitive training (spatial vs. perceptual training) and physical training (endurance training vs. non-endurance training) on spatial learning and associated brain activation in 33 adults (40-55 years). Spatial learning was assessed with a virtual maze task, and at the same time neural correlates were measured with functional magnetic resonance imaging (fMRI).Only the spatial training improved performance in the maze task. These behavioral gains were accompanied by a decrease in frontal and temporal lobe activity. At posttest, participants of the spatial training group showed lower activity than participants of the perceptual training group in a network of brain regions associated with spatial learning, including the hippocampus and parahippocampal gyrus. No significant differences were observed between the two physical intervention groups.Functional changes in neural systems associated with spatial navigation can be induced by cognitive interventions and seem to be stronger than effects of physical exercise in middle-aged adults.
536 _ _ |a 344 - Clinical and Health Care Research (POF3-344)
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542 _ _ |i 2013-07-20
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|u http://creativecommons.org/licenses/by/2.0
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650 _ 7 |a Oxygen
|0 S88TT14065
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650 _ 2 |a Adult
|2 MeSH
650 _ 2 |a Brain: blood supply
|2 MeSH
650 _ 2 |a Brain: physiology
|2 MeSH
650 _ 2 |a Brain Mapping
|2 MeSH
650 _ 2 |a Executive Function: physiology
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Image Processing, Computer-Assisted
|2 MeSH
650 _ 2 |a Magnetic Resonance Imaging
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Maze Learning
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Neuropsychological Tests
|2 MeSH
650 _ 2 |a Oxygen: blood
|2 MeSH
650 _ 2 |a Oxygen Consumption: physiology
|2 MeSH
650 _ 2 |a Physical Endurance
|2 MeSH
650 _ 2 |a Physical Fitness: physiology
|2 MeSH
650 _ 2 |a Space Perception: physiology
|2 MeSH
650 _ 2 |a User-Computer Interface
|2 MeSH
650 _ 2 |a Verbal Learning: physiology
|2 MeSH
700 1 _ |a Holzschneider, Kathrin
|0 P:(DE-HGF)0
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700 1 _ |a Stenzel, Anna
|0 P:(DE-HGF)0
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700 1 _ |a Wolbers, Thomas
|0 P:(DE-2719)2810583
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700 1 _ |a Röder, Brigitte
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773 1 8 |a 10.1186/1471-2202-14-73
|b : Springer Science and Business Media LLC, 2013-07-20
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|t BMC Neuroscience
|v 14
|y 2013
|x 1471-2202
773 _ _ |a 10.1186/1471-2202-14-73
|g Vol. 14, no. 1, p. 73
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|q 14:1<73
|p 73
|t BMC neuroscience
|v 14
|y 2013
|x 1471-2202
856 4 _ |y OpenAccess
|u https://pub.dzne.de/record/137003/files/DZNE-2020-03325.pdf
856 4 _ |y OpenAccess
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856 7 _ |2 Pubmed Central
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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913 1 _ |a DE-HGF
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914 1 _ |y 2013
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