TY  - JOUR
AU  - Cashdollar, Nathan
AU  - Lavie, Nilli
AU  - Düzel, Emrah
TI  - Alleviating memory impairment through distraction.
JO  - The journal of neuroscience
VL  - 33
IS  - 48
SN  - 0270-6474
CY  - Washington, DC
PB  - Soc.57413
M1  - DZNE-2020-03473
SP  - 19012-19022
PY  - 2013
AB  - Distraction typically has a negative impact on memory for recent events and patients with existing memory impairment are particularly vulnerable to distractor interference. In contrast, here we establish a beneficial effect for distractor presentation in humans for both patients with memory impairment due to bilateral hippocampal lesions and healthy adults with low memory performance. Recognition memory for images of place scenes, which had to be memorized for short delay periods was significantly improved with the presentation of a distractor face during the delay. Magnetoencephalography recordings of neural oscillations in the theta frequency range obtained in healthy adults suggest that this memory improvement results from the interruption of rehearsal by the distractor. Our results highlight circumstances where active memory rehearsal may paradoxically increase memory impairments and distraction alleviates these memory deficits in patients with hippocampal injury and healthy adults.
KW  - Adult
KW  - Analysis of Variance
KW  - Artifacts
KW  - Epilepsy, Temporal Lobe: complications
KW  - Epilepsy, Temporal Lobe: psychology
KW  - Face
KW  - Female
KW  - Hippocampus: injuries
KW  - Hippocampus: physiopathology
KW  - Humans
KW  - Magnetoencephalography
KW  - Male
KW  - Memory Disorders: physiopathology
KW  - Memory Disorders: psychology
KW  - Middle Aged
KW  - Photic Stimulation
KW  - Psychomotor Performance: physiology
KW  - Recognition, Psychology: physiology
KW  - Sclerosis
KW  - Theta Rhythm: physiology
KW  - Wavelet Analysis
LB  - PUB:(DE-HGF)16
C6  - pmid:24285905
C2  - pmc:PMC6618708
DO  - DOI:10.1523/JNEUROSCI.1797-13.2013
UR  - https://pub.dzne.de/record/137151
ER  -