%0 Journal Article
%A Szentkiralyi, Andras
%A Völzke, Henry
%A Hoffmann, Wolfgang
%A Baune, Bernhard T
%A Berger, Klaus
%T The relationship between depressive symptoms and restless legs syndrome in two prospective cohort studies.
%J Psychosomatic medicine
%V 75
%N 4
%@ 0033-3174
%C Philadelphia, Pa.
%I Lippincott Williams & Wilkins
%M DZNE-2020-03553
%P 359-365
%D 2013
%X Cross-sectional studies suggest a strong association between depression and restless legs syndrome (RLS); however, the temporal relationship between the two disorders remains unknown. We tested whether the presence of clinically relevant depressive symptoms (CRDS) is a risk factor for subsequent RLS in the general population. The relationship between prevalent RLS and incident CRDS was also examined.Two independent, prospective cohort studies with representative, age-stratified random samples, the Dortmund Health Study (DHS; n = 1312/1122 [baseline/follow-up], median follow-up time = 2.1 years) and the Study of Health in Pomerania (SHIP; n = 4308/3300, median follow-up time = 5.0 years) were analyzed. RLS was assessed in both studies according to the RLS minimal criteria, at baseline and at follow-up. CRDS were assessed by the Center for Epidemiologic Studies-Depression scale (a score of ≥16) in DHS only at baseline and by the Munich-Composite International Diagnostic-Screener in SHIP at baseline and at follow-up.Clinically relevant depressive symptoms at baseline were associated new-onset RLS in both studies (DHS: odds ratio [OR] = 1.94, 95
%K Adult
%K Aged
%K Comorbidity
%K Depression: epidemiology
%K Female
%K Follow-Up Studies
%K Germany: epidemiology
%K Health Surveys
%K Humans
%K Incidence
%K Male
%K Middle Aged
%K Motor Activity
%K Obesity: epidemiology
%K Prevalence
%K Prospective Studies
%K Restless Legs Syndrome: epidemiology
%K Restless Legs Syndrome: psychology
%K Risk Factors
%K Sampling Studies
%K Smoking: epidemiology
%K Surveys and Questionnaires
%K Young Adult
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:23576767
%R 10.1097/PSY.0b013e31828bbbf1
%U https://pub.dzne.de/record/137231