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@ARTICLE{Fischer:137404,
      author       = {Fischer, Andre},
      title        = {{E}pigenetic memory: the {L}amarckian brain.},
      journal      = {The EMBO journal},
      volume       = {33},
      number       = {9},
      issn         = {0261-4189},
      address      = {Hoboken, NJ [u.a.]},
      publisher    = {Wiley},
      reportid     = {DZNE-2020-03726},
      pages        = {945-967},
      year         = {2014},
      abstract     = {Recent data support the view that epigenetic processes play
                      a role in memory consolidation and help to transmit acquired
                      memories even across generations in a Lamarckian manner.
                      Drugs that target the epigenetic machinery were found to
                      enhance memory function in rodents and ameliorate disease
                      phenotypes in models for brain diseases such as Alzheimer's
                      disease, Chorea Huntington, Depression or Schizophrenia. In
                      this review, I will give an overview on the current
                      knowledge of epigenetic processes in memory function and
                      brain disease with a focus on Morbus Alzheimer as the most
                      common neurodegenerative disease. I will address the
                      question whether an epigenetic therapy could indeed be a
                      suitable therapeutic avenue to treat brain diseases and
                      discuss the necessary steps that should help to take
                      neuroepigenetic research to the next level.},
      subtyp        = {Review Article},
      keywords     = {Alzheimer Disease: genetics / Alzheimer Disease:
                      physiopathology / Animals / Brain: physiopathology /
                      Epigenesis, Genetic / Gene Expression Regulation / Histones:
                      metabolism / Humans / Memory / RNA, Untranslated: physiology
                      / Histones (NLM Chemicals) / RNA, Untranslated (NLM
                      Chemicals)},
      cin          = {AG Fischer},
      ddc          = {570},
      cid          = {I:(DE-2719)1410002},
      pnm          = {342 - Disease Mechanisms and Model Systems (POF3-342)},
      pid          = {G:(DE-HGF)POF3-342},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:24719207},
      pmc          = {pmc:PMC4193930},
      doi          = {10.1002/embj.201387637},
      url          = {https://pub.dzne.de/record/137404},
}