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001     137631
005     20240109095554.0
024 7 _ |a 10.1007/s00115-014-4088-5
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024 7 _ |a pmid:25294667
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024 7 _ |a 0028-2804
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024 7 _ |a 1433-0407
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037 _ _ |a DZNE-2020-03953
041 _ _ |a ger
082 _ _ |a 610
100 1 _ |a Huber, M.
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|e Corresponding author
245 _ _ |a [Drug safety: challenge in an aging society].
260 _ _ |a Heidelberg
|c 2014
|b Springer
264 _ 1 |3 online
|2 Crossref
|b Springer Science and Business Media LLC
|c 2014-10-09
264 _ 1 |3 print
|2 Crossref
|b Springer Science and Business Media LLC
|c 2014-11-01
336 7 _ |a article
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336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a Within the context of the demographic change the proportion of the elderly in the overall population is steadily increasing. At the same time elderly patients are prescribed a disproportionately high number of medicines in comparison to younger patients. In the light of multimorbidity and polypharmacy which affect a relevant portion of the older population, drug safety is of particular importance.In recent years, the prescription of psychiatric drugs to elderly patients was repeatedly subjected to regulatory assessment and recommendations, for example the safety of antipsychotics in patients with dementia. As only limited information is often available with respect to the risks of medicines in the elderly population, additional efforts are necessary for improvement of the database. In this context, the system of spontaneous reporting, e.g. the reporting of cases of suspected adverse drug reactions to the responsible authorities, plays an important role with respect to the additional knowledge to be gathered. By reporting observed adverse drug reactions as well as by the quality of the reported information, physicians are able to significantly influence the effectiveness of this system in a positive way.As medical care for the majority of the elderly population is provided by general practitioners, adequate longitudinal studies are of special interest for investigating drug safety in the elderly. This aim is being pursued by the AgeCoDe study (German study on aging, cognition and dementia in primary care patients), a prospective, multicentre observational study, which is being carried out within the German competence network of degenerative dementia (Kompetenznetz Degenerative Demenzen).
536 _ _ |a 345 - Population Studies and Genetics (POF3-345)
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542 _ _ |i 2014-10-09
|2 Crossref
|u http://www.springer.com/tdm
588 _ _ |a Dataset connected to CrossRef, PubMed,
650 _ 7 |a Antipsychotic Agents
|2 NLM Chemicals
650 _ 2 |a Adverse Drug Reaction Reporting Systems: organization & administration
|2 MeSH
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a Antipsychotic Agents: adverse effects
|2 MeSH
650 _ 2 |a Drug Prescriptions: statistics & numerical data
|2 MeSH
650 _ 2 |a Drug-Related Side Effects and Adverse Reactions: epidemiology
|2 MeSH
650 _ 2 |a Drug-Related Side Effects and Adverse Reactions: etiology
|2 MeSH
650 _ 2 |a Drug-Related Side Effects and Adverse Reactions: prevention & control
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Germany: epidemiology
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Incidence
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Mandatory Reporting
|2 MeSH
650 _ 2 |a Mental Disorders: drug therapy
|2 MeSH
650 _ 2 |a Mental Disorders: epidemiology
|2 MeSH
650 _ 2 |a Risk Assessment
|2 MeSH
650 _ 2 |a Risk Factors
|2 MeSH
700 1 _ |a Blumberg, A.
|0 P:(DE-HGF)0
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700 1 _ |a Chatterjee, S.
|0 P:(DE-HGF)0
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700 1 _ |a Hänisch, Britta
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700 1 _ |a Schlosser-Weber, G.
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700 1 _ |a Broich, K.
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773 1 8 |a 10.1007/s00115-014-4088-5
|b : Springer Science and Business Media LLC, 2014-10-09
|n 11
|p 1352-1362
|3 journal-article
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|t Der Nervenarzt
|v 85
|y 2014
|x 0028-2804
773 _ _ |a 10.1007/s00115-014-4088-5
|g Vol. 85, no. 11, p. 1352 - 1362
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856 4 _ |u https://pub.dzne.de/record/137631/files/DZNE-2020-03953.pdf
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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999 C 5 |2 Crossref
|o
999 C 5 |9 -- missing cx lookup --
|a 10.1001/archinte.1997.00440350031003
|2 Crossref
|o 10.1001/archinte.1997.00440350031003
999 C 5 |9 -- missing cx lookup --
|a 10.1370/afm.1337
|2 Crossref
|o 10.1370/afm.1337
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|2 Crossref
|o 10.1136/bmj.38330.470486.8F
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|2 Crossref
|o 10.1176/appi.ajp.161.6.1113
999 C 5 |y 2010
|2 Crossref
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999 C 5 |y 2013
|2 Crossref
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999 C 5 |9 -- missing cx lookup --
|a 10.1001/archgenpsychiatry.2010.30
|2 Crossref
|o 10.1001/archgenpsychiatry.2010.30
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|o 10.1371/journal.pone.0016852
999 C 5 |9 -- missing cx lookup --
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|2 Crossref
|o 10.1111/acps.12129
999 C 5 |y 2012
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999 C 5 |9 -- missing cx lookup --
|a 10.1007/978-3-642-37124-0_47
|2 Crossref
|o 10.1007/978-3-642-37124-0_47
999 C 5 |y 2010
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999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.jclinepi.2012.07.019
|2 Crossref
|o 10.1016/j.jclinepi.2012.07.019
999 C 5 |9 -- missing cx lookup --
|a 10.1024/1011-6877.22.1.17
|2 Crossref
|o 10.1024/1011-6877.22.1.17
999 C 5 |9 -- missing cx lookup --
|a 10.1007/s00103-013-1767-5
|2 Crossref
|o 10.1007/s00103-013-1767-5

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