000137719 001__ 137719
000137719 005__ 20240321220312.0
000137719 0247_ $$2doi$$a10.1016/j.neurobiolaging.2014.04.003
000137719 0247_ $$2pmid$$apmid:24952995
000137719 0247_ $$2ISSN$$a0197-4580
000137719 0247_ $$2ISSN$$a1558-1497
000137719 0247_ $$2altmetric$$aaltmetric:2488415
000137719 037__ $$aDZNE-2020-04041
000137719 041__ $$aEnglish
000137719 082__ $$a610
000137719 1001_ $$0P:(DE-2719)2810641$$aBates, Sarah$$b0$$eFirst author
000137719 245__ $$aHow cognitive aging affects multisensory integration of navigational cues.
000137719 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2014
000137719 264_1 $$2Crossref$$3print$$bElsevier BV$$c2014-12-01
000137719 3367_ $$2DRIVER$$aarticle
000137719 3367_ $$2DataCite$$aOutput Types/Journal article
000137719 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1707926545_4695
000137719 3367_ $$2BibTeX$$aARTICLE
000137719 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000137719 3367_ $$00$$2EndNote$$aJournal Article
000137719 520__ $$aEntorhinal grid cells and hippocampal place cells are key systems for mammalian navigation. By combining information from different sensory modalities, they provide abstract representations of space. Given that both structures are among the earliest to undergo age-related neurodegenerative changes, we asked whether age-related navigational impairments are related to deficient integration of navigational cues. Younger and older adults performed a homing task that required using visual landmarks, self-motion information, or a combination of both. Further, a conflict between cues assessed the influence of each sensory domain. Our findings revealed performance impairments in the older adults, suggestive of a higher noise in the underlying spatial representations. In addition, even though both groups integrated visual and self-motion information to become more accurate and precise, older adults did not place as much influence on visual information as would have been optimal. As these findings were unrelated to potential changes in balance or spatial working memory, this study provides the first evidence that increasing noise and a suboptimal weighting of navigational cues might contribute to the common problems with spatial representations experienced by many older adults. These findings are discussed in the context of the known age-related changes in the entorhinal-hippocampal network.
000137719 536__ $$0G:(DE-HGF)POF3-344$$a344 - Clinical and Health Care Research (POF3-344)$$cPOF3-344$$fPOF III$$x0
000137719 542__ $$2Crossref$$i2014-12-01$$uhttps://www.elsevier.com/tdm/userlicense/1.0/
000137719 588__ $$aDataset connected to CrossRef, PubMed,
000137719 650_2 $$2MeSH$$aAdult
000137719 650_2 $$2MeSH$$aAged
000137719 650_2 $$2MeSH$$aAged, 80 and over
000137719 650_2 $$2MeSH$$aAging: pathology
000137719 650_2 $$2MeSH$$aAging: physiology
000137719 650_2 $$2MeSH$$aAging: psychology
000137719 650_2 $$2MeSH$$aAnimals
000137719 650_2 $$2MeSH$$aCognition: physiology
000137719 650_2 $$2MeSH$$aCues
000137719 650_2 $$2MeSH$$aEntorhinal Cortex: cytology
000137719 650_2 $$2MeSH$$aEntorhinal Cortex: pathology
000137719 650_2 $$2MeSH$$aEntorhinal Cortex: physiology
000137719 650_2 $$2MeSH$$aFemale
000137719 650_2 $$2MeSH$$aHippocampus: cytology
000137719 650_2 $$2MeSH$$aHippocampus: pathology
000137719 650_2 $$2MeSH$$aHippocampus: physiology
000137719 650_2 $$2MeSH$$aHoming Behavior: physiology
000137719 650_2 $$2MeSH$$aHumans
000137719 650_2 $$2MeSH$$aMale
000137719 650_2 $$2MeSH$$aMiddle Aged
000137719 650_2 $$2MeSH$$aNoise
000137719 650_2 $$2MeSH$$aSensation: physiology
000137719 650_2 $$2MeSH$$aSpatial Memory: physiology
000137719 650_2 $$2MeSH$$aSpatial Navigation: physiology
000137719 650_2 $$2MeSH$$aVisual Perception: physiology
000137719 650_2 $$2MeSH$$aYoung Adult
000137719 7001_ $$0P:(DE-2719)2810583$$aWolbers, Thomas$$b1$$eLast author
000137719 77318 $$2Crossref$$3journal-article$$a10.1016/j.neurobiolaging.2014.04.003$$b : Elsevier BV, 2014-12-01$$n12$$p2761-2769$$tNeurobiology of Aging$$v35$$x0197-4580$$y2014
000137719 773__ $$0PERI:(DE-600)1498414-3$$a10.1016/j.neurobiolaging.2014.04.003$$gVol. 35, no. 12, p. 2761 - 2769$$n12$$p2761-2769$$q35:12<2761 - 2769$$tNeurobiology of aging$$v35$$x0197-4580$$y2014
000137719 8564_ $$uhttps://pub.dzne.de/record/137719/files/DZNE-2020-04041_Restricted.pdf
000137719 8564_ $$uhttps://pub.dzne.de/record/137719/files/DZNE-2020-04041_Restricted.pdf?subformat=pdfa$$xpdfa
000137719 909CO $$ooai:pub.dzne.de:137719$$pVDB
000137719 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810641$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
000137719 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810583$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000137719 9131_ $$0G:(DE-HGF)POF3-344$$1G:(DE-HGF)POF3-340$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lErkrankungen des Nervensystems$$vClinical and Health Care Research$$x0
000137719 9141_ $$y2014
000137719 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000137719 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000137719 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000137719 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bNEUROBIOL AGING : 2017
000137719 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000137719 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search
000137719 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC
000137719 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000137719 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000137719 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000137719 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000137719 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000137719 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000137719 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5
000137719 9201_ $$0I:(DE-2719)1310002$$kAG Wolbers$$lAging, Cognition and Technology$$x0
000137719 980__ $$ajournal
000137719 980__ $$aVDB
000137719 980__ $$aI:(DE-2719)1310002
000137719 980__ $$aUNRESTRICTED