%0 Journal Article
%A Brüggemann, Norbert
%A Kühn, Andrea
%A Schneider, Susanne A
%A Kamm, Christoph
%A Wolters, Alexander
%A Krause, Patricia
%A Moro, Elena
%A Steigerwald, Frank
%A Wittstock, Matthias
%A Tronnier, Volker
%A Lozano, Andres M
%A Hamani, Clement
%A Poon, Yu-Yan
%A Zittel, Simone
%A Wächter, Tobias
%A Deuschl, Günther
%A Krüger, Rejko
%A Kupsch, Andreas
%A Münchau, Alexander
%A Lohmann, Katja
%A Volkmann, Jens
%A Klein, Christine
%T Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia.
%J Neurology
%V 84
%N 9
%@ 0028-3878
%C [S.l.]
%I Ovid
%M DZNE-2020-04130
%P 895-903
%D 2015
%X Deep brain stimulation of the internal pallidum (GPi-DBS) is an established therapeutic option in treatment-refractory dystonia, and the identification of factors predicting surgical outcome is needed to optimize patient selection.In this retrospective multicenter study, GPi-DBS outcome of 8 patients with DYT6, 9 with DYT1, and 38 with isolated dystonia without known monogenic cause (non-DYT) was assessed at early (1-16 months) and late (22-92 months) follow-up using Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) scores.At early follow-up, mean reduction of dystonia severity was greater in patients with DYT1 (BFMDRS score: -60
%K Adolescent
%K Adult
%K Child
%K Child, Preschool
%K Deep Brain Stimulation: methods
%K Deep Brain Stimulation: trends
%K Dystonia: diagnosis
%K Dystonia: therapy
%K Electrodes, Implanted
%K Female
%K Follow-Up Studies
%K Globus Pallidus: physiopathology
%K Humans
%K Male
%K Middle Aged
%K Retrospective Studies
%K Treatment Outcome
%K Young Adult
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:25653290
%2 pmc:PMC6170184
%R 10.1212/WNL.0000000000001312
%U https://pub.dzne.de/record/137808