TY  - JOUR
AU  - Brüggemann, Norbert
AU  - Kühn, Andrea
AU  - Schneider, Susanne A
AU  - Kamm, Christoph
AU  - Wolters, Alexander
AU  - Krause, Patricia
AU  - Moro, Elena
AU  - Steigerwald, Frank
AU  - Wittstock, Matthias
AU  - Tronnier, Volker
AU  - Lozano, Andres M
AU  - Hamani, Clement
AU  - Poon, Yu-Yan
AU  - Zittel, Simone
AU  - Wächter, Tobias
AU  - Deuschl, Günther
AU  - Krüger, Rejko
AU  - Kupsch, Andreas
AU  - Münchau, Alexander
AU  - Lohmann, Katja
AU  - Volkmann, Jens
AU  - Klein, Christine
TI  - Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia.
JO  - Neurology
VL  - 84
IS  - 9
SN  - 0028-3878
CY  - [S.l.]
PB  - Ovid
M1  - DZNE-2020-04130
SP  - 895-903
PY  - 2015
AB  - Deep brain stimulation of the internal pallidum (GPi-DBS) is an established therapeutic option in treatment-refractory dystonia, and the identification of factors predicting surgical outcome is needed to optimize patient selection.In this retrospective multicenter study, GPi-DBS outcome of 8 patients with DYT6, 9 with DYT1, and 38 with isolated dystonia without known monogenic cause (non-DYT) was assessed at early (1-16 months) and late (22-92 months) follow-up using Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) scores.At early follow-up, mean reduction of dystonia severity was greater in patients with DYT1 (BFMDRS score: -60
KW  - Adolescent
KW  - Adult
KW  - Child
KW  - Child, Preschool
KW  - Deep Brain Stimulation: methods
KW  - Deep Brain Stimulation: trends
KW  - Dystonia: diagnosis
KW  - Dystonia: therapy
KW  - Electrodes, Implanted
KW  - Female
KW  - Follow-Up Studies
KW  - Globus Pallidus: physiopathology
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - Young Adult
LB  - PUB:(DE-HGF)16
C6  - pmid:25653290
C2  - pmc:PMC6170184
DO  - DOI:10.1212/WNL.0000000000001312
UR  - https://pub.dzne.de/record/137808
ER  -