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@ARTICLE{Maa:137972,
author = {Maaß, Anne and Berron, David and Libby, Laura A and
Ranganath, Charan and Düzel, Emrah},
title = {{F}unctional subregions of the human entorhinal cortex.},
journal = {eLife},
volume = {4},
issn = {2050-084X},
address = {Cambridge},
publisher = {eLife Sciences Publications},
reportid = {DZNE-2020-04294},
pages = {e06426},
year = {2015},
abstract = {The entorhinal cortex (EC) is the primary site of
interactions between the neocortex and hippocampus. Studies
in rodents and nonhuman primates suggest that EC can be
divided into subregions that connect differentially with
perirhinal cortex (PRC) vs parahippocampal cortex (PHC) and
with hippocampal subfields along the proximo-distal axis.
Here, we used high-resolution functional magnetic resonance
imaging at 7 Tesla to identify functional subdivisions of
the human EC. In two independent datasets, PRC showed
preferential intrinsic functional connectivity with
anterior-lateral EC and PHC with posterior-medial EC. These
EC subregions, in turn, exhibited differential connectivity
with proximal and distal subiculum. In contrast,
connectivity of PRC and PHC with subiculum followed not only
a proximal-distal but also an anterior-posterior gradient.
Our data provide the first evidence that the human EC can be
divided into functional subdivisions whose functional
connectivity closely parallels the known anatomical
connectivity patterns of the rodent and nonhuman primate
EC.},
keywords = {Adult / Connectome: methods / Entorhinal Cortex: anatomy
$\&$ histology / Entorhinal Cortex: physiology / Female /
Hippocampus: physiology / Humans / Magnetic Resonance
Imaging / Male / Memory: physiology / Neural Pathways:
physiology / Species Specificity / Visual Perception:
physiology},
cin = {AG Düzel},
ddc = {600},
cid = {I:(DE-2719)5000006},
pnm = {344 - Clinical and Health Care Research (POF3-344)},
pid = {G:(DE-HGF)POF3-344},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:26052749},
pmc = {pmc:PMC4458841},
doi = {10.7554/eLife.06426},
url = {https://pub.dzne.de/record/137972},
}