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@ARTICLE{Ernst:138141,
      author       = {Ernst, A. and Schlattmann, P. and Waldfahrer, F. and
                      Westhofen, M.},
      title        = {{B}21 {C}haracterisation {O}f {M}ice {O}verexpressing
                      {M}utant {H}untingtin {L}acking {T}he {S}pine
                      {M}orphogenesis {R}egulator {K}alirin-7},
      journal      = {Journal of neurology, neurosurgery, and psychiatry},
      volume       = {85},
      number       = {Suppl 1},
      issn         = {0022-3050},
      address      = {London},
      publisher    = {BMJ Publishing Group},
      reportid     = {DZNE-2020-04463},
      pages        = {A16-A16},
      year         = {2017},
      abstract     = {The BEMED study (BMJ 2016; 352: DOI 10.1136) was designed
                      as multi-centric, double-blind, plaebo-controlled study in
                      patients with Menière's disease. It should compare a
                      low-level (2 × 24 mg/d) vs. high-level
                      (3 × 48 mg/d) betahstine intake vs. placebo. The
                      primary endpoint was the 'number of vertigo attacks lasting
                      longer than 20 min as documented in a patient's diary'.
                      The main finding of the study was that betahistine did not
                      significantly better reduced the number of vertigo attacks
                      than placebo. Therefore, the BEMED study should be
                      critically discussed in the present paper.},
      subtyp        = {Editorial},
      keywords     = {Adolescent / Adult / Aged / Aged, 80 and over /
                      Betahistine: therapeutic use / Dose-Response Relationship,
                      Drug / Double-Blind Method / Female / Germany / Humans /
                      Male / Meniere Disease: classification / Meniere Disease:
                      diagnosis / Meniere Disease: drug therapy / Middle Aged /
                      Young Adult / Betahistine (NLM Chemicals)},
      cin          = {AG N.N. 3},
      ddc          = {610},
      cid          = {I:(DE-2719)1240015},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28850992},
      doi          = {10.1136/jnnp-2014-309032.49},
      url          = {https://pub.dzne.de/record/138141},
}