guest ::
| Home > Publications Database > Targeting intrinsically disordered proteins in rational drug discovery. > print |
| Home > Publications Database > Targeting intrinsically disordered proteins in rational drug discovery. > print |
| 001 | 138314 | ||
| 005 | 20240321220419.0 | ||
| 024 | 7 | _ | |a 10.1517/17460441.2016.1107041 |2 doi |
| 024 | 7 | _ | |a pmid:26549326 |2 pmid |
| 024 | 7 | _ | |a 1746-0441 |2 ISSN |
| 024 | 7 | _ | |a 1746-045X |2 ISSN |
| 024 | 7 | _ | |a altmetric:4745118 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-04636 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Ambadipudi, Susmitha |0 P:(DE-2719)2811405 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a Targeting intrinsically disordered proteins in rational drug discovery. |
| 260 | _ | _ | |a Abingdon |c 2016 |b Taylor & Francis Group |
| 264 | _ | 1 | |3 online |2 Crossref |b Informa Healthcare |c 2015-11-07 |
| 264 | _ | 1 | |3 print |2 Crossref |b Informa Healthcare |c 2016-01-02 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1685004056_32154 |2 PUB:(DE-HGF) |x Review Article |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs) have gained wide recognition over the past decade due to their versatile roles in cell physiology and pathology. A large repertoire of IDPs/IDPRs has been implicated in numerous diseases, making them potential targets for therapeutic intervention. Recent advances in experimental methods and computational approaches have enabled detection and characterization of these highly dynamic proteins at atomistic detail, thus facilitating disorder/dynamic-based drug discovery.This article presents an overview of the functional relevance and pathological implications of IDPs/IDPRs in cells. The authors outline the currently available experimental methods employed for structural characterization of these proteins. They also exemplify the practical limitations encountered during such characterization and ways to overcome them. Taken together, the article discusses the plausibility of exploiting protein disorder for drug targeting.Disorder-based drug targeting is gearing up in the realm of novel drug discovery approaches. Tools for probing the molecular features of IDPs and IDPRs are rapidly improving and start to provide accurate descriptions of the complex ensembles populated by IDPs/IDPRs. They thus pave the way for the development of drug molecules, which specifically target disease-associated disorder. |
| 536 | _ | _ | |a 342 - Disease Mechanisms and Model Systems (POF3-342) |0 G:(DE-HGF)POF3-342 |c POF3-342 |f POF III |x 0 |
| 542 | _ | _ | |i 2015-11-07 |2 Crossref |u http://creativecommons.org/licenses/by/4.0/ |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 650 | _ | 7 | |a Intrinsically Disordered Proteins |2 NLM Chemicals |
| 650 | _ | 2 | |a Animals |2 MeSH |
| 650 | _ | 2 | |a Drug Design |2 MeSH |
| 650 | _ | 2 | |a Drug Discovery: methods |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Intrinsically Disordered Proteins: metabolism |2 MeSH |
| 650 | _ | 2 | |a Models, Molecular |2 MeSH |
| 650 | _ | 2 | |a Molecular Targeted Therapy |2 MeSH |
| 650 | _ | 2 | |a Protein Conformation |2 MeSH |
| 700 | 1 | _ | |a Zweckstetter, Markus |0 P:(DE-2719)2810591 |b 1 |e Last author |u dzne |
| 773 | 1 | 8 | |a 10.1517/17460441.2016.1107041 |b : Informa Healthcare, 2015-11-07 |n 1 |p 65-77 |3 journal-article |2 Crossref |t Expert Opinion on Drug Discovery |v 11 |y 2015 |x 1746-0441 |
| 773 | _ | _ | |a 10.1517/17460441.2016.1107041 |g Vol. 11, no. 1, p. 65 - 77 |0 PERI:(DE-600)2272966-5 |n 1 |q 11:1<65 - 77 |p 65-77 |t Expert opinion on drug discovery |v 11 |y 2016 |x 1746-0441 |
| 856 | 4 | _ | |y OpenAccess |u https://pub.dzne.de/record/138314/files/DZNE-2020-04636.pdf |
| 856 | 4 | _ | |y OpenAccess |x pdfa |u https://pub.dzne.de/record/138314/files/DZNE-2020-04636.pdf?subformat=pdfa |
| 909 | C | O | |o oai:pub.dzne.de:138314 |p openaire |p open_access |p VDB |p driver |p dnbdelivery |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)2811405 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 1 |6 P:(DE-2719)2810591 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-342 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Disease Mechanisms and Model Systems |x 0 |
| 914 | 1 | _ | |y 2016 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a Creative Commons Attribution CC BY 4.0 |0 LIC:(DE-HGF)CCBY4 |2 HGFVOC |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b EXPERT OPIN DRUG DIS : 2017 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |
| 920 | 1 | _ | |0 I:(DE-2719)1410001 |k AG Zweckstetter |l Structural Biology in Dementia |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-2719)1410001 |
| 980 | 1 | _ | |a FullTexts |
| 999 | C | 5 | |2 Crossref |t Papers of special note have been highlighted as either of interest (•) or of considerable interest (••) to readers |o Papers of special note have been highlighted as either of interest (•) or of considerable interest (••) to readers |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/227561a0 |2 Crossref |o 10.1038/227561a0 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1006/jmbi.1999.3110 |2 Crossref |o 10.1006/jmbi.1999.3110 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nbt0901-805 |2 Crossref |o 10.1038/nbt0901-805 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.bbapap.2010.01.011 |2 Crossref |o 10.1016/j.bbapap.2010.01.011 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrm3920 |2 Crossref |o 10.1038/nrm3920 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/cbic.201200093 |2 Crossref |o 10.1002/cbic.201200093 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr400688u |2 Crossref |o 10.1021/cr400688u |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrm1589 |2 Crossref |o 10.1038/nrm1589 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.sbi.2011.04.001 |2 Crossref |o 10.1016/j.sbi.2011.04.001 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.sbi.2012.08.008 |2 Crossref |o 10.1016/j.sbi.2012.08.008 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1042/BJ20121346 |2 Crossref |o 10.1042/BJ20121346 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/bi012159+ |2 Crossref |o 10.1021/bi012159+ |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1110/ps.4210102 |2 Crossref |o 10.1110/ps.4210102 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.bbapap.2010.01.017 |2 Crossref |o 10.1016/j.bbapap.2010.01.017 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.abb.2012.09.010 |2 Crossref |o 10.1016/j.abb.2012.09.010 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nature13999 |2 Crossref |o 10.1038/nature13999 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2003.10.002 |2 Crossref |o 10.1016/j.str.2003.10.002 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.jmb.2004.02.002 |2 Crossref |o 10.1016/j.jmb.2004.02.002 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0034687 |2 Crossref |o 10.1371/journal.pone.0034687 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr400695p |2 Crossref |o 10.1021/cr400695p |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr400713r |2 Crossref |o 10.1021/cr400713r |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/bi047993o |2 Crossref |o 10.1021/bi047993o |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3390/ijms160819490 |2 Crossref |o 10.3390/ijms160819490 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/bioinformatics/bti537 |2 Crossref |o 10.1093/bioinformatics/bti537 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1146/annurev.biophys.37.032807.125924 |2 Crossref |o 10.1146/annurev.biophys.37.032807.125924 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/nar/gkl893 |2 Crossref |o 10.1093/nar/gkl893 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/nar/gkt960 |2 Crossref |o 10.1093/nar/gkt960 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1126/science.1132814 |2 Crossref |o 10.1126/science.1132814 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.0507916103 |2 Crossref |o 10.1073/pnas.0507916103 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pcbi.1000552 |2 Crossref |o 10.1371/journal.pcbi.1000552 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.coph.2012.04.003 |2 Crossref |o 10.1016/j.coph.2012.04.003 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1039/c2mb25102g |2 Crossref |o 10.1039/c2mb25102g |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.tibs.2012.05.001 |2 Crossref |o 10.1016/j.tibs.2012.05.001 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.sbi.2011.03.011 |2 Crossref |o 10.1016/j.sbi.2011.03.011 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.cbpa.2010.08.022 |2 Crossref |o 10.1016/j.cbpa.2010.08.022 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/128_2012_411 |2 Crossref |o 10.1007/128_2012_411 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.M111.265835 |2 Crossref |o 10.1074/jbc.M111.265835 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1096/fj.04-1584rev |2 Crossref |o 10.1096/fj.04-1584rev |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3390/ijms151223090 |2 Crossref |o 10.3390/ijms151223090 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2010.08.009 |2 Crossref |o 10.1016/j.str.2010.08.009 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.M110.199885 |2 Crossref |o 10.1074/jbc.M110.199885 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1006276107 |2 Crossref |o 10.1073/pnas.1006276107 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1586/epr.10.36 |2 Crossref |o 10.1586/epr.10.36 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1186/1471-2164-10-S1-S12 |2 Crossref |o 10.1186/1471-2164-10-S1-S12 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1186/1471-2164-10-S1-S7 |2 Crossref |o 10.1186/1471-2164-10-S1-S7 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nature10317 |2 Crossref |o 10.1038/nature10317 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s12017-013-8257-7 |2 Crossref |o 10.1007/s12017-013-8257-7 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3389/fmolb.2014.00006 |2 Crossref |o 10.3389/fmolb.2014.00006 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrc2763 |2 Crossref |o 10.1038/nrc2763 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.ccr.2014.01.021 |2 Crossref |o 10.1016/j.ccr.2014.01.021 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/cdd.2010.35 |2 Crossref |o 10.1038/cdd.2010.35 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0092-8674(02)01284-9 |2 Crossref |o 10.1016/S0092-8674(02)01284-9 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1128/MCB.19.1.1 |2 Crossref |o 10.1128/MCB.19.1.1 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja900616b |2 Crossref |o 10.1021/ja900616b |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.tibtech.2006.07.005 |2 Crossref |o 10.1016/j.tibtech.2006.07.005 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0065-230X(08)60523-0 |2 Crossref |o 10.1016/S0065-230X(08)60523-0 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.85.20.7763 |2 Crossref |o 10.1073/pnas.85.20.7763 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/bi060981d |2 Crossref |o 10.1021/bi060981d |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/srep09659 |2 Crossref |o 10.1038/srep09659 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/360674a0 |2 Crossref |o 10.1038/360674a0 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1504081112 |2 Crossref |o 10.1073/pnas.1504081112 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/anie.201501714 |2 Crossref |o 10.1002/anie.201501714 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1586/14789450.5.2.207 |2 Crossref |o 10.1586/14789450.5.2.207 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/0197-4580(95)00025-A |2 Crossref |o 10.1016/0197-4580(95)00025-A |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.M512786200 |2 Crossref |o 10.1074/jbc.M512786200 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/ncomms1255 |2 Crossref |o 10.1038/ncomms1255 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0165-0173(00)00019-9 |2 Crossref |o 10.1016/S0165-0173(00)00019-9 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.M114.611368 |2 Crossref |o 10.1074/jbc.M114.611368 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.2174/156720511796717177 |2 Crossref |o 10.2174/156720511796717177 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1146/annurev.neuro.24.1.1121 |2 Crossref |o 10.1146/annurev.neuro.24.1.1121 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrn3549 |2 Crossref |o 10.1038/nrn3549 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja312471h |2 Crossref |o 10.1021/ja312471h |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.0500466102 |2 Crossref |o 10.1073/pnas.0500466102 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.0406361102 |2 Crossref |o 10.1073/pnas.0406361102 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1517/14712598.2011.552884 |2 Crossref |o 10.1517/14712598.2011.552884 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.273.16.9443 |2 Crossref |o 10.1074/jbc.273.16.9443 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1146/annurev.cellbio.042308.113313 |2 Crossref |o 10.1146/annurev.cellbio.042308.113313 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrneurol.2012.242 |2 Crossref |o 10.1038/nrneurol.2012.242 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/emboj/18.4.815 |2 Crossref |o 10.1093/emboj/18.4.815 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/978-1-61779-551-0_12 |2 Crossref |o 10.1007/978-1-61779-551-0_12 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/bi501460a |2 Crossref |o 10.1021/bi501460a |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.jmb.2007.12.016 |2 Crossref |o 10.1016/j.jmb.2007.12.016 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0076-6879(10)72010-3 |2 Crossref |o 10.1016/S0076-6879(10)72010-3 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1201802109 |2 Crossref |o 10.1073/pnas.1201802109 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1209527109 |2 Crossref |o 10.1073/pnas.1209527109 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nature12294 |2 Crossref |o 10.1038/nature12294 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.semcdb.2014.09.027 |2 Crossref |o 10.1016/j.semcdb.2014.09.027 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.0809232106 |2 Crossref |o 10.1073/pnas.0809232106 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/anie.201000378 |2 Crossref |o 10.1002/anie.201000378 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja407009w |2 Crossref |o 10.1021/ja407009w |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr400297g |2 Crossref |o 10.1021/cr400297g |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1322611111 |2 Crossref |o 10.1073/pnas.1322611111 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1313006111 |2 Crossref |o 10.1073/pnas.1313006111 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nmeth.3475 |2 Crossref |o 10.1038/nmeth.3475 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1039/C1MB05275F |2 Crossref |o 10.1039/C1MB05275F |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja105657f |2 Crossref |o 10.1021/ja105657f |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/iub.1045 |2 Crossref |o 10.1002/iub.1045 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.jmr.2013.11.011 |2 Crossref |o 10.1016/j.jmr.2013.11.011 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s10858-014-9872-9 |2 Crossref |o 10.1007/s10858-014-9872-9 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/BF00175245 |2 Crossref |o 10.1007/BF00175245 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.sbi.2007.01.009 |2 Crossref |o 10.1016/j.sbi.2007.01.009 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2009.08.001 |2 Crossref |o 10.1016/j.str.2009.08.001 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3390/molecules180910802 |2 Crossref |o 10.3390/molecules180910802 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2015.06.002 |2 Crossref |o 10.1016/j.str.2015.06.002 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja101645g |2 Crossref |o 10.1021/ja101645g |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.0407146102 |2 Crossref |o 10.1073/pnas.0407146102 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja044834j |2 Crossref |o 10.1021/ja044834j |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2013.10.020 |2 Crossref |o 10.1016/j.str.2013.10.020 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pbio.1000034 |2 Crossref |o 10.1371/journal.pbio.1000034 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr0404287 |2 Crossref |o 10.1021/cr0404287 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ar700189y |2 Crossref |o 10.1021/ar700189y |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja904716h |2 Crossref |o 10.1021/ja904716h |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.str.2013.09.014 |2 Crossref |o 10.1016/j.str.2013.09.014 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/ja209931w |2 Crossref |o 10.1021/ja209931w |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.sbi.2013.12.006 |2 Crossref |o 10.1016/j.sbi.2013.12.006 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1039/c3cp53558d |2 Crossref |o 10.1039/c3cp53558d |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/anie.201305094 |2 Crossref |o 10.1002/anie.201305094 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/bioinformatics/btu824 |2 Crossref |o 10.1093/bioinformatics/btu824 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.cbpa.2010.06.169 |2 Crossref |o 10.1016/j.cbpa.2010.06.169 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.chembiol.2008.09.011 |2 Crossref |o 10.1016/j.chembiol.2008.09.011 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1042/BST20120086 |2 Crossref |o 10.1042/BST20120086 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0041070 |2 Crossref |o 10.1371/journal.pone.0041070 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pcbi.1003249 |2 Crossref |o 10.1371/journal.pcbi.1003249 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nchembio.1528 |2 Crossref |o 10.1038/nchembio.1528 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.tibs.2015.07.004 |2 Crossref |o 10.1016/j.tibs.2015.07.004 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/ncomms6857 |2 Crossref |o 10.1038/ncomms6857 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/jm501440q |2 Crossref |o 10.1021/jm501440q |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.neurobiolaging.2010.12.012 |2 Crossref |o 10.1016/j.neurobiolaging.2010.12.012 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3233/JAD-142874 |2 Crossref |o 10.3233/JAD-142874 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/anie.201208290 |2 Crossref |o 10.1002/anie.201208290 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0087133 |2 Crossref |o 10.1371/journal.pone.0087133 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/bi961799n |2 Crossref |o 10.1021/bi961799n |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1074/jbc.M113.524520 |2 Crossref |o 10.1074/jbc.M113.524520 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s13311-012-0105-1 |2 Crossref |o 10.1007/s13311-012-0105-1 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S1474-4422(10)70119-8 |2 Crossref |o 10.1016/S1474-4422(10)70119-8 |
| 999 | C | 5 | |y 2004 |2 Crossref |o Chene P 2004 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrd4236 |2 Crossref |o 10.1038/nrd4236 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/sj.onc.1206641 |2 Crossref |o 10.1038/sj.onc.1206641 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1021/cr4004049 |2 Crossref |o 10.1021/cr4004049 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.pharmthera.2014.08.003 |2 Crossref |o 10.1016/j.pharmthera.2014.08.003 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.18632/oncotarget.3868 |2 Crossref |o 10.18632/oncotarget.3868 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|