guest ::
| Home > Publications Database > Genome Editing in Mice Using TALE Nucleases. > print |
| 001 | 138334 | ||
| 005 | 20250416111447.0 | ||
| 020 | _ | _ | |a 978-1-4939-2931-3 (print) |
| 020 | _ | _ | |a 978-1-4939-2932-0 (electronic) |
| 024 | 7 | _ | |a 10.1007/978-1-4939-2932-0_17 |2 doi |
| 024 | 7 | _ | |a pmid:26443225 |2 pmid |
| 024 | 7 | _ | |a 1064-3745 |2 ISSN |
| 024 | 7 | _ | |a 1940-6029 |2 ISSN |
| 024 | 7 | _ | |a altmetric:4603489 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-04656 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Wefers, Benedikt |0 P:(DE-2719)2810988 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a Genome Editing in Mice Using TALE Nucleases. |
| 260 | _ | _ | |a [Heidelberg] |c 2016 |b [Springer] |
| 264 | _ | 1 | |3 print |2 Crossref |b Springer New York |c 2016-01-01 |
| 295 | 1 | 0 | |a TALENs / Kühn, Ralf (Editor) ; New York, NY : Springer New York, 2016, Chapter 17 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-2931-3=978-1-4939-2932-0 ; doi:10.1007/978-1-4939-2932-0 |
| 300 | _ | _ | |a 229 - 243 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Book |0 PUB:(DE-HGF)3 |2 PUB:(DE-HGF) |m book |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1744794791_2859 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 490 | 0 | _ | |a Methods in Molecular Biology |v 1338 |
| 520 | _ | _ | |a Gene engineering for generating targeted mouse mutants is a key technology for biomedical research. Using TALENs as sequence-specific nucleases to induce targeted double-strand breaks, the mouse genome can be directly modified in zygotes in a single step without the need for embryonic stem cells. By embryo microinjection of TALEN mRNAs and targeting vectors, knockout and knock-in alleles can be generated fast and efficiently. In this chapter we provide protocols for the application of TALENs in mouse zygotes. |
| 536 | _ | _ | |a 342 - Disease Mechanisms and Model Systems (POF3-342) |0 G:(DE-HGF)POF3-342 |c POF3-342 |f POF III |x 0 |
| 542 | _ | _ | |i 2016-01-01 |2 Crossref |u http://www.springer.com/tdm |
| 588 | _ | _ | |a Dataset connected to CrossRef Book Series, PubMed, |
| 650 | _ | 7 | |a RNA, Messenger |2 NLM Chemicals |
| 650 | _ | 7 | |a Endonucleases |0 EC 3.1.- |2 NLM Chemicals |
| 650 | _ | 2 | |a Animals |2 MeSH |
| 650 | _ | 2 | |a Animals, Genetically Modified: genetics |2 MeSH |
| 650 | _ | 2 | |a DNA Breaks, Double-Stranded |2 MeSH |
| 650 | _ | 2 | |a Endonucleases: genetics |2 MeSH |
| 650 | _ | 2 | |a Gene Knockout Techniques: methods |2 MeSH |
| 650 | _ | 2 | |a Genome |2 MeSH |
| 650 | _ | 2 | |a Mice |2 MeSH |
| 650 | _ | 2 | |a Microinjections |2 MeSH |
| 650 | _ | 2 | |a Mutation |2 MeSH |
| 650 | _ | 2 | |a RNA Editing: genetics |2 MeSH |
| 650 | _ | 2 | |a RNA, Messenger: genetics |2 MeSH |
| 700 | 1 | _ | |a Brandl, Christina |b 1 |
| 700 | 1 | _ | |a Ortiz, Oskar |b 2 |
| 700 | 1 | _ | |a Wurst, Wolfgang |0 P:(DE-2719)2000028 |b 3 |u dzne |
| 700 | 1 | _ | |a Kühn, Ralf |b 4 |
| 773 | 1 | 8 | |a 10.1007/978-1-4939-2932-0_17 |b : Springer New York, 2016-01-01 |p 229-243 |3 book-chapter |2 Crossref |t TALENs |y 2016 |x 1064-3745 |
| 773 | _ | _ | |a 10.1007/978-1-4939-2932-0_17 |0 PERI:(DE-600)2493551-7 |p 229-243 |t Methods in molecular biology |v 1338 |y 2016 |x 1064-3745 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/138334/files/DZNE-2020-04656_Restricted.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/138334/files/DZNE-2020-04656_Restricted.pdf?subformat=pdfa |x pdfa |
| 909 | C | O | |p VDB |o oai:pub.dzne.de:138334 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)2810988 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 3 |6 P:(DE-2719)2000028 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-342 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Disease Mechanisms and Model Systems |x 0 |
| 914 | 1 | _ | |y 2016 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2020-01-17 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |d 2020-01-17 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2020-01-17 |
| 920 | 1 | _ | |0 I:(DE-2719)1140001 |k AG Wurst |l Genome Engineering |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a book |
| 980 | _ | _ | |a I:(DE-2719)1140001 |
| 980 | _ | _ | |a UNRESTRICTED |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrg1619 |2 Crossref |o 10.1038/nrg1619 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1009424107 |2 Crossref |o 10.1073/pnas.1009424107 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1534/genetics.110.117002 |2 Crossref |o 10.1534/genetics.110.117002 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1126/science.1178811 |2 Crossref |o 10.1126/science.1178811 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1126/science.1178817 |2 Crossref |o 10.1126/science.1178817 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1534/genetics.110.120717 |2 Crossref |o 10.1534/genetics.110.120717 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nbt.1755 |2 Crossref |o 10.1038/nbt.1755 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1146/annurev-genet-051710-150955 |2 Crossref |o 10.1146/annurev-genet-051710-150955 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1146/annurev.biochem.052308.093131 |2 Crossref |o 10.1146/annurev.biochem.052308.093131 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nbt.2477 |2 Crossref |o 10.1038/nbt.2477 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/srep03136 |2 Crossref |o 10.1038/srep03136 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1089/scd.2014.0466 |2 Crossref |o 10.1089/scd.2014.0466 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.febslet.2014.09.014 |2 Crossref |o 10.1016/j.febslet.2014.09.014 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1073/pnas.1218721110 |2 Crossref |o 10.1073/pnas.1218721110 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1534/genetics.113.156570 |2 Crossref |o 10.1534/genetics.113.156570 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.fob.2014.11.009 |2 Crossref |o 10.1016/j.fob.2014.11.009 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0060216 |2 Crossref |o 10.1371/journal.pone.0060216 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/nar/gkt258 |2 Crossref |o 10.1093/nar/gkt258 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s10529-013-1387-z |2 Crossref |o 10.1007/s10529-013-1387-z |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0076004 |2 Crossref |o 10.1371/journal.pone.0076004 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1128/MCB.00023-14 |2 Crossref |o 10.1128/MCB.00023-14 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/srep05705 |2 Crossref |o 10.1038/srep05705 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/ncomms4045 |2 Crossref |o 10.1038/ncomms4045 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/dvg.22731 |2 Crossref |o 10.1002/dvg.22731 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|