%0 Journal Article
%A Elshehabi, Morad
%A Maier, Katrin S
%A Hasmann, Sandra E
%A Nussbaum, Susanne
%A Herbst, Heinz
%A Heger, Tanja
%A Berg, Daniela
%A Hobert, Markus A
%A Maetzler, Walter
%T Limited Effect of Dopaminergic Medication on Straight Walking and Turning in Early-to-Moderate Parkinson's Disease during Single and Dual Tasking.
%J Frontiers in aging neuroscience
%V 8
%@ 1663-4365
%C Lausanne
%I Frontiers Research Foundation
%M DZNE-2020-04672
%P 4
%D 2016
%X In Parkinson's disease (PD), the effects of dopaminergic medication on straight walking and turning were mainly investigated under single tasking (ST) conditions. However, multitasking situations are considered more daily relevant.Thirty-nine early-to-moderate PD patients performed the following standardized ST and dual tasks as fast as possible for 1 min during On- and Off-medication while wearing inertial sensors: straight walking and turning, checking boxes, and subtracting serial 7s. Quantitative gait parameters as well as velocity of the secondary tasks were analyzed.The following parameters improved significantly in On-medication during ST: gait velocity during straight walking (p = 0.03); step duration (p = 0.048) and peak velocity (p = 0.04) during turning; velocity of checking boxes during ST (p = 0.04) and DT (p = 0.04). Velocity of checking boxes was the only parameter that also improved during DT.These results suggest that dopaminergic medication does not relevantly influence straight walking and turning in early-to-moderate PD during DT.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:26858638
%2 pmc:PMC4728201
%R 10.3389/fnagi.2016.00004
%U https://pub.dzne.de/record/138350