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@ARTICLE{Elshehabi:138350,
      author       = {Elshehabi, Morad and Maier, Katrin S and Hasmann, Sandra E
                      and Nussbaum, Susanne and Herbst, Heinz and Heger, Tanja and
                      Berg, Daniela and Hobert, Markus A and Maetzler, Walter},
      title        = {{L}imited {E}ffect of {D}opaminergic {M}edication on
                      {S}traight {W}alking and {T}urning in {E}arly-to-{M}oderate
                      {P}arkinson's {D}isease during {S}ingle and {D}ual
                      {T}asking.},
      journal      = {Frontiers in aging neuroscience},
      volume       = {8},
      issn         = {1663-4365},
      address      = {Lausanne},
      publisher    = {Frontiers Research Foundation},
      reportid     = {DZNE-2020-04672},
      pages        = {4},
      year         = {2016},
      abstract     = {In Parkinson's disease (PD), the effects of dopaminergic
                      medication on straight walking and turning were mainly
                      investigated under single tasking (ST) conditions. However,
                      multitasking situations are considered more daily
                      relevant.Thirty-nine early-to-moderate PD patients performed
                      the following standardized ST and dual tasks as fast as
                      possible for 1 min during On- and Off-medication while
                      wearing inertial sensors: straight walking and turning,
                      checking boxes, and subtracting serial 7s. Quantitative gait
                      parameters as well as velocity of the secondary tasks were
                      analyzed.The following parameters improved significantly in
                      On-medication during ST: gait velocity during straight
                      walking (p = 0.03); step duration (p = 0.048) and
                      peak velocity (p = 0.04) during turning; velocity of
                      checking boxes during ST (p = 0.04) and DT
                      (p = 0.04). Velocity of checking boxes was the only
                      parameter that also improved during DT.These results suggest
                      that dopaminergic medication does not relevantly influence
                      straight walking and turning in early-to-moderate PD during
                      DT.},
      cin          = {AG Maetzler / Ext UKT-Trend ; Ext UKT-Trend / Ext UKT ; Ext
                      UKT / AG Berg ; AG Berg / AG Gasser 1},
      ddc          = {610},
      cid          = {I:(DE-2719)5000024 / I:(DE-2719)5000056 /
                      I:(DE-2719)5000058 / I:(DE-2719)5000055 /
                      I:(DE-2719)1210000},
      pnm          = {344 - Clinical and Health Care Research (POF3-344) / 345 -
                      Population Studies and Genetics (POF3-345)},
      pid          = {G:(DE-HGF)POF3-344 / G:(DE-HGF)POF3-345},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:26858638},
      pmc          = {pmc:PMC4728201},
      doi          = {10.3389/fnagi.2016.00004},
      url          = {https://pub.dzne.de/record/138350},
}