TY  - JOUR
AU  - Craig, Michael
AU  - Wolbers, Thomas
AU  - Harris, Mathew A
AU  - Hauff, Patrick
AU  - Della Sala, Sergio
AU  - Dewar, Michaela
TI  - Comparable rest-related promotion of spatial memory consolidation in younger and older adults.
JO  - Neurobiology of aging
VL  - 48
SN  - 0197-4580
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DZNE-2020-05185
SP  - 143-152
PY  - 2016
AB  - Flexible spatial navigation depends on cognitive mapping, a function that declines with increasing age. In young adults, a brief period of postnavigation rest promotes the consolidation and integration of spatial memories into accurate cognitive maps. We examined (1) whether rest promotes spatial memory consolidation and integration in older adults; and (2) whether the magnitude of the rest benefit changes with increasing age. Young and older adults learned a route through a virtual environment, followed by a 10-minute delay comprising either wakeful rest or a perceptual task, and a subsequent cognitive mapping task, requiring the pointing to landmarks from different locations. Pointing accuracy was lower in the older than younger adults. However, there was a comparable rest-related enhancement in pointing accuracy in the 2 age groups. Together our findings suggest that (1) the age-related decline in cognitive mapping cannot be explained by increased consolidation interference in older adults; and (2) as we grow older, rest continues to support the consolidation and integration of spatial memories.
KW  - Adult
KW  - Aged
KW  - Aging: physiology
KW  - Aging: psychology
KW  - Female
KW  - Humans
KW  - Male
KW  - Memory Consolidation: physiology
KW  - Middle Aged
KW  - Rest: physiology
KW  - Spatial Memory: physiology
KW  - Wakefulness: physiology
KW  - Young Adult
LB  - PUB:(DE-HGF)16
C6  - pmid:27689512
C2  - pmc:PMC5604729
DO  - DOI:10.1016/j.neurobiolaging.2016.08.007
UR  - https://pub.dzne.de/record/138863
ER  -