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000139688 0247_ $$2doi$$a10.1002/hipo.22808
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000139688 0247_ $$2ISSN$$a1050-9631
000139688 0247_ $$2ISSN$$a1098-1063
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000139688 037__ $$aDZNE-2020-06010
000139688 041__ $$aEnglish
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000139688 1001_ $$0P:(DE-HGF)0$$aHansen, Niels$$b0$$eCorresponding author
000139688 245__ $$aMemory encoding-related anterior hippocampal potentials are modulated by deep brain stimulation of the entorhinal area.
000139688 260__ $$aNew York, NY [u.a.]$$bWiley$$c2018
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000139688 520__ $$aDeep brain stimulation (DBS) of the human entorhinal area using 50 Hz pulses has revealed conflicting results regarding memory performance. Moreover, its impact on memory-related hippocampal potentials has not yet been investigated.We recorded data from seven epilepsy patients implanted with depth electrodes in the entorhinal cortex, hippocampus, amygdala, and parahippocampal cortex. Entorhinal DBS (bipolar, biphasic 50 Hz pulses, on- and off-cycles of 15 s) was applied with low amplitude (0.1 mA) to resemble physiologic conditions. During DBS on- and off-periods, patients learned noun-color associations that were later tested.During entorhinal DBS we observed more positive deflections of event-related potentials (ranging from 700 to 950 ms) in the anterior hippocampus for the on- vs. off-condition. We detected no effects in the amygdala, mid hippocampus and parahippocampal cortex. On the behavioral level, no differences in memory performance (item and source memory) were apparent in the on- vs. off-condition, neither across all trials nor across patients.Our findings indicate that entorhinal DBS with low amplitude has an impact on memory encoding-related potentials within the anterior hippocampus, but not on memory performance per se.
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000139688 542__ $$2Crossref$$i2017-10-30$$uhttp://doi.wiley.com/10.1002/tdm_license_1.1
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000139688 650_2 $$2MeSH$$aAdult
000139688 650_2 $$2MeSH$$aAmygdala: physiology
000139688 650_2 $$2MeSH$$aAmygdala: physiopathology
000139688 650_2 $$2MeSH$$aAssociation Learning: physiology
000139688 650_2 $$2MeSH$$aDeep Brain Stimulation: methods
000139688 650_2 $$2MeSH$$aEntorhinal Cortex: physiology
000139688 650_2 $$2MeSH$$aEntorhinal Cortex: physiopathology
000139688 650_2 $$2MeSH$$aEpilepsy, Temporal Lobe: physiopathology
000139688 650_2 $$2MeSH$$aEpilepsy, Temporal Lobe: psychology
000139688 650_2 $$2MeSH$$aEpilepsy, Temporal Lobe: therapy
000139688 650_2 $$2MeSH$$aEvoked Potentials
000139688 650_2 $$2MeSH$$aFemale
000139688 650_2 $$2MeSH$$aHippocampus: physiology
000139688 650_2 $$2MeSH$$aHippocampus: physiopathology
000139688 650_2 $$2MeSH$$aHumans
000139688 650_2 $$2MeSH$$aMale
000139688 650_2 $$2MeSH$$aMemory: physiology
000139688 7001_ $$aChaieb, Leila$$b1
000139688 7001_ $$aDerner, Marlene$$b2
000139688 7001_ $$aHampel, Kevin G$$b3
000139688 7001_ $$aElger, Christian E$$b4
000139688 7001_ $$aSurges, Rainer$$b5
000139688 7001_ $$aStaresina, Bernhard$$b6
000139688 7001_ $$0P:(DE-2719)2000052$$aAxmacher, Nikolai$$b7$$udzne
000139688 7001_ $$aFell, Juergen$$b8
000139688 77318 $$2Crossref$$3journal-article$$a10.1002/hipo.22808$$b : Wiley, 2017-10-30$$n1$$p12-17$$tHippocampus$$v28$$x1050-9631$$y2017
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000139688 999C5 $$2Crossref$$oAugustinack 2010$$y2010
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1126/science.aaa5694$$o10.1126/science.aaa5694
000139688 999C5 $$2Crossref$$oChen 2010$$y2010
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2011.06.086$$o10.1016/j.neuroimage.2011.06.086
000139688 999C5 $$2Crossref$$oDuvernoy The human hippocampus. Functional anatomy, vascularisation and serial sections with MRI 2013$$tThe human hippocampus. Functional anatomy, vascularisation and serial sections with MRI$$y2013
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.brs.2012.08.001$$o10.1016/j.brs.2012.08.001
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.tics.2006.06.003$$o10.1016/j.tics.2006.06.003
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuron.2010.06.005$$o10.1016/j.neuron.2010.06.005
000139688 999C5 $$2Crossref$$oGrill Indwelling neural implants: Strategies for contending with the in vivo environment 2008$$tIndwelling neural implants: Strategies for contending with the in vivo environment$$y2008
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1162/089892999563526$$o10.1162/089892999563526
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1002/hipo.22436$$o10.1002/hipo.22436
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuroimage.2016.06.021$$o10.1016/j.neuroimage.2016.06.021
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.neuron.2016.10.062$$o10.1016/j.neuron.2016.10.062
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1523/JNEUROSCI.4368-15.2016$$o10.1523/JNEUROSCI.4368-15.2016
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1002/hipo.20081$$o10.1002/hipo.20081
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1002/(SICI)1097-0193(1999)8:4<194::AID-HBM4>3.0.CO;2-C$$o10.1002/(SICI)1097-0193(1999)8:4<194::AID-HBM4>3.0.CO;2-C
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/B978-0-444-53497-2.00025-5$$o10.1016/B978-0-444-53497-2.00025-5
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.tics.2013.09.002$$o10.1016/j.tics.2013.09.002
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1162/jocn.2008.20507$$o10.1162/jocn.2008.20507
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/j.jneumeth.2007.03.024$$o10.1016/j.jneumeth.2007.03.024
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1038/nn.3154$$o10.1038/nn.3154
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1056/NEJMoa1107212$$o10.1056/NEJMoa1107212
000139688 999C5 $$2Crossref$$9-- missing cx lookup --$$a10.1016/S0079-6123(07)63003-9$$o10.1016/S0079-6123(07)63003-9