TY  - JOUR
AU  - Monaco, Cynthia M F
AU  - Hughes, Meghan C
AU  - Ramos, Sofhia V
AU  - Varah, Nina E
AU  - Lamberz, Christian
AU  - Rahman, Fasih A
AU  - McGlory, Chris
AU  - Tarnopolsky, Mark A
AU  - Krause, Matthew P
AU  - Laham, Robert
AU  - Hawke, Thomas J
AU  - Perry, Christopher G R
TI  - Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes.
JO  - Diabetologia
VL  - 61
IS  - 6
SN  - 0012-186X
CY  - Heidelberg
PB  - Springer
M1  - DZNE-2020-06259
SP  - 1411-1423
PY  - 2018
AB  - A comprehensive assessment of skeletal muscle ultrastructure and mitochondrial bioenergetics has not been undertaken in individuals with type 1 diabetes. This study aimed to systematically assess skeletal muscle mitochondrial phenotype in young adults with type 1 diabetes.Physically active, young adults (men and women) with type 1 diabetes (HbA1c 63.0 ± 16.0 mmol/mol [7.9
KW  - Adult
KW  - Body Mass Index
KW  - Calcium: chemistry
KW  - Diabetes Mellitus, Type 1: metabolism
KW  - Diabetes Mellitus, Type 1: pathology
KW  - Energy Metabolism
KW  - Exercise: physiology
KW  - Female
KW  - Humans
KW  - Hydrogen Peroxide: metabolism
KW  - Insulin: metabolism
KW  - Male
KW  - Microscopy, Electron, Transmission
KW  - Microscopy, Fluorescence
KW  - Mitochondria: metabolism
KW  - Mitochondria: ultrastructure
KW  - Muscle, Skeletal: metabolism
KW  - Muscle, Skeletal: pathology
KW  - Muscle, Skeletal: ultrastructure
KW  - Oxygen Consumption
KW  - Young Adult
KW  - Insulin (NLM Chemicals)
KW  - Hydrogen Peroxide (NLM Chemicals)
KW  - Calcium (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:29666899
DO  - DOI:10.1007/s00125-018-4602-6
UR  - https://pub.dzne.de/record/139937
ER  -