% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Mauschitz:140206,
      author       = {Mauschitz, Matthias M and Bonnemaijer, Pieter W M and
                      Diers, Kersten and Rauscher, Franziska G and Elze, Tobias
                      and Engel, Christoph and Loeffler, Markus and Colijn,
                      Johanna Maria and Ikram, M Arfan and Vingerling, Johannes R
                      and Williams, Katie M and Hammond, Christopher J and
                      Creuzot-Garcher, Catherine and Bron, Alain M and Silva,
                      Rufino and Nunes, Sandrina and Delcourt, Cécile and
                      Cougnard-Grégoire, Audrey and Holz, Frank G and Klaver,
                      Caroline C W and Breteler, Monique M B and Finger, Robert P
                      and Epidemiology, European Eye and Acar, Niyazi and
                      Anastosopoulos, Eleftherios and Azuara-Blanco, Augusto and
                      Berendschot, Tos and Berendschot, Tos and Bergen, Arthur and
                      Bertelsen, Geir and Binquet, Christine and Bird, Alan and
                      Bobak, Martin and Larsen, Morten Bøgelund and Boon, Camiel
                      and Bourne, Rupert and Brétillon, Lionel and Broe, Rebecca
                      and Bron, Alain and Buitendijk, Gabrielle and Cachulo, Maria
                      Luz and Capuano, Vittorio and Carrière, Isabelle and
                      Chakravarthy, Usha and Chan, Michelle and Chang, Petrus and
                      Colijn, Johanna and Cougnard-Grégoire, Audrey and Cree,
                      Angela and Creuzot-Garcher, Catherine and Cumberland,
                      Phillippa and Cunha-Vaz, José and Daien, Vincent and De
                      Jong, Eiko and Deak, Gabor and Delcourt, Cécile and
                      Delyfer, Marie-Noëlle and Hollander, Anneke den and
                      Dietzel, Martha and Erke, Maja Gran and Faria, Pedro and
                      Farinha, Claudia and Fauser, Sascha and Finger, Robert and
                      Fletcher, Astrid and Foster, Paul and Founti, Panayiota and
                      Gorgels, Theo and Grauslund, Jakob and Grus, Franz and
                      Hammond, Christopher and Hense, Hans-Werner and Hermann,
                      Manuel and Hoehn, René and Hogg, Ruth and Holz, Frank and
                      Hoyng, Carel and Jansonius, Nomdo and Janssen, Sarah and
                      Kersten, Eveline and Khawaja, Anthony and Klaver, Caroline
                      and Korobelnik, Jean-François and Lamparter, Julia and Le
                      Goff, Mélanie and Lechanteur, Yara and Lehtimäki, Terho
                      and Leung, Irene and Lotery, Andrew and Meester, Magda and
                      Merle, Bénédicte and Meyer Zu Westrup, Verena and Midena,
                      Edoardo and Miotto, Stefania and Mirshahi, Alireza and
                      Mohan-Saïd, Sadek and Mueller, Michael and Muldrew, Alyson
                      and Murta, Joaquim and Nickels, Stefan and Nunes, Sandrina
                      and Owen, Christopher and Peto, Tunde and Pfeiffer, Norbert
                      and Piermarocchi, Stefano and Prokofyeva, Elena and Rahi,
                      Jugnoo and Raitakari, Olli and Rauscher, Franziska and
                      Ribeiro, Luisa and Rougier, Marie-Bénédicte and Rudnicka,
                      Alicja and Sahel, José and Salonikiou, Aggeliki and
                      Sanchez, Clarisa and Schmitz-Valckenberg, Steffen and
                      Schuster, Alexander and Schweitzer, Cédric and Segato,
                      Tatiana and Shehata, Jasmin and Silva, Rufino and Silvestri,
                      Giuliana and Simader, Christian and Souied, Eric and
                      Speckauskas, Martynas and Springelkamp, Henriet and Tapp,
                      Robyn and Topouzis, Fotis and van Leeuwen, Elisa and
                      Verhoeven, Virginie and Verzijden, Timo and Von Hanno,
                      Therese and Wiedemann, Peter and Williams, Katie and
                      Wolfram, Christian and Yip, Jennifer and Zerbib, Jennyfer},
      title        = {{S}ystemic and {O}cular {D}eterminants of {P}eripapillary
                      {R}etinal {N}erve {F}iber {L}ayer {T}hickness {M}easurements
                      in the {E}uropean {E}ye {E}pidemiology ({E}3) {P}opulation.},
      journal      = {Ophthalmology},
      volume       = {125},
      number       = {10},
      issn         = {0161-6420},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DZNE-2020-06528},
      pages        = {1526-1536},
      year         = {2018},
      abstract     = {To investigate systemic and ocular determinants of
                      peripapillary retinal nerve fiber layer thickness (pRNFLT)
                      in the European population.Cross-sectional meta-analysis.A
                      total of 16 084 European adults from 8 cohort studies (mean
                      age range, 56.9±12.3-82.1±4.2 years) of the European Eye
                      Epidemiology (E3) consortium.We examined associations with
                      pRNFLT measured by spectral-domain OCT in each study using
                      multivariable linear regression and pooled results using
                      random effects meta-analysis.Determinants of pRNFLT.Mean
                      pRNFLT ranged from 86.8±21.4 μm in the Rotterdam Study I
                      to 104.7±12.5 μm in the Rotterdam Study III. We found the
                      following factors to be associated with reduced pRNFLT:
                      Older age (β = -0.38 μm/year; $95\%$ confidence interval
                      [CI], -0.57 to -0.18), higher intraocular pressure (IOP) (β
                      = -0.36 μm/mmHg; $95\%$ CI, -0.56 to -0.15), visual
                      impairment (β = -5.50 μm; $95\%$ CI, -9.37 to -1.64), and
                      history of systemic hypertension (β = -0.54 μm; $95\%$
                      CI, -1.01 to -0.07) and stroke (β = -1.94 μm; $95\%$ CI,
                      -3.17 to -0.72). A suggestive, albeit nonsignificant,
                      association was observed for dementia (β = -3.11 μm;
                      $95\%$ CI, -6.22 to 0.01). Higher pRNFLT was associated with
                      more hyperopic spherical equivalent (β = 1.39 μm/diopter;
                      $95\%$ CI, 1.19-1.59) and smoking (β = 1.53 μm; $95\%$
                      CI, 1.00-2.06 for current smokers compared with
                      never-smokers).In addition to previously described
                      determinants such as age and refraction, we found that
                      systemic vascular and neurovascular diseases were associated
                      with reduced pRNFLT. These may be of clinical relevance,
                      especially in glaucoma monitoring of patients with newly
                      occurring vascular comorbidities.},
      keywords     = {Cross-Sectional Studies / Disease Progression / Europe:
                      epidemiology / Glaucoma: diagnosis / Glaucoma: epidemiology
                      / Glaucoma: physiopathology / Humans / Intraocular Pressure:
                      physiology / Nerve Fibers: pathology / Optic Disk: pathology
                      / Population Surveillance: methods / Retinal Ganglion Cells:
                      pathology / Tomography, Optical Coherence: methods},
      cin          = {AG Breteler},
      ddc          = {610},
      cid          = {I:(DE-2719)1012001},
      pnm          = {345 - Population Studies and Genetics (POF3-345)},
      pid          = {G:(DE-HGF)POF3-345},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29716786},
      doi          = {10.1016/j.ophtha.2018.03.026},
      url          = {https://pub.dzne.de/record/140206},
}