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@ARTICLE{Heser:140211,
      author       = {Heser, Kathrin and Pohontsch, Nadine Janis and Scherer,
                      Martin and Löffler, Antje and Luck, Tobias and
                      Riedel-Heller, Steffi G and Maier, Wolfgang and Parker,
                      Debora and Haenisch, Britta and Jessen, Frank},
      title        = {{P}erspective of elderly patients on chronic use of
                      potentially inappropriate medication - {R}esults of the
                      qualitative {CIM}-{TRIAD} study.},
      journal      = {PLOS ONE},
      volume       = {13},
      number       = {9},
      issn         = {1932-6203},
      address      = {San Francisco, California, US},
      publisher    = {PLOS},
      reportid     = {DZNE-2020-06533},
      pages        = {e0202068},
      year         = {2018},
      abstract     = {Although potentially inappropriate medication (PIM) is
                      associated with risk of harm due to adverse effects, it is
                      frequently prescribed for elderly patients. The aim of this
                      qualitative multi-center study was to gain insight into
                      contextual factors that might lead to chronic PIM use. We
                      conducted semi-structured interviews with elderly patients
                      with or without chronic PIM use (patient interviews: n =
                      52). Patients were between 86 and 96 years old. The
                      participants were recruited from the AgeCoDe study.
                      Interviews were audiotaped and transcribed verbatim. The
                      transcripts of the interviews were analysed using
                      qualitative content analysis. Deductive and inductive
                      categories were determined. We found contextual factors
                      related to the patient and related to patient-general
                      practitioner (GP) communication that might lead to chronic
                      PIM use (i.e., positive features of PIM, maintaining
                      characteristics of medication intake, barriers to
                      deprescribe PIM, external actors supporting PIM intake,
                      system-related factors). Besides certain health-related
                      behaviours (e.g., own obligation to report to GP) and
                      medication-related attitudes and knowledge (e.g., awareness
                      of side effects and interaction of medicines),
                      patient-GP-interactions that were characterised by mutual
                      agreements on drugs (e.g., concerning dosage or
                      discontinuation of a drug) might be advantageous to reduce
                      the probability of chronic PIM use. The results might assist
                      in the development of guidelines and educational programs
                      aiming to reduce PIM use in the elderly.},
      keywords     = {Aged / Aged, 80 and over / Drug-Related Side Effects and
                      Adverse Reactions: diagnosis / Drug-Related Side Effects and
                      Adverse Reactions: prevention $\&$ control / Female /
                      General Practitioners: statistics $\&$ numerical data /
                      Humans / Inappropriate Prescribing: statistics $\&$
                      numerical data / Interviews as Topic / Male / Patients:
                      statistics $\&$ numerical data / Potentially Inappropriate
                      Medication List: statistics $\&$ numerical data /
                      Qualitative Research / Risk Assessment: methods / Risk
                      Assessment: statistics $\&$ numerical data / Risk Factors},
      cin          = {AG Hänisch / AG Jessen},
      ddc          = {610},
      cid          = {I:(DE-2719)1013010 / I:(DE-2719)1011102},
      pnm          = {344 - Clinical and Health Care Research (POF3-344) / 345 -
                      Population Studies and Genetics (POF3-345)},
      pid          = {G:(DE-HGF)POF3-344 / G:(DE-HGF)POF3-345},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30231027},
      pmc          = {pmc:PMC6145513},
      doi          = {10.1371/journal.pone.0202068},
      url          = {https://pub.dzne.de/record/140211},
}