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@ARTICLE{Diersch:140474,
      author       = {Diersch, Nadine and Wolbers, Thomas},
      title        = {{T}he potential of virtual reality for spatial navigation
                      research across the adult lifespan.},
      journal      = {The journal of experimental biology},
      volume       = {222},
      number       = {Suppl 1},
      issn         = {0022-0949},
      address      = {Cambridge},
      reportid     = {DZNE-2020-06796},
      pages        = {jeb187252},
      year         = {2019},
      abstract     = {Older adults often experience serious problems in spatial
                      navigation, and alterations in underlying brain structures
                      are among the first indicators for a progression to
                      neurodegenerative diseases. Studies investigating the neural
                      mechanisms of spatial navigation and its changes across the
                      adult lifespan are increasingly using virtual reality (VR)
                      paradigms. VR offers major benefits in terms of ecological
                      validity, experimental control and options to track
                      behavioral responses. However, navigation in the real world
                      differs from navigation in VR in several aspects. In
                      addition, the importance of body-based or visual cues for
                      navigation varies between animal species. Incongruences
                      between sensory and motor input in VR might consequently
                      affect their performance to a different degree. After
                      discussing the specifics of using VR in spatial navigation
                      research across species, we outline several challenges when
                      investigating age-related deficits in spatial navigation
                      with the help of VR. In addition, we discuss ways to reduce
                      their impact, together with the possibilities VR offers for
                      improving navigational abilities in older adults.},
      subtyp        = {Review Article},
      keywords     = {Aged / Aged, 80 and over / Cues / Humans / Spatial
                      Navigation / Virtual Reality},
      cin          = {AG Wolbers},
      ddc          = {570},
      cid          = {I:(DE-2719)1310002},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30728232},
      doi          = {10.1242/jeb.187252},
      url          = {https://pub.dzne.de/record/140474},
}